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Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response
Published 2019“…From a panel of tested proteins and genes, we found that the levels of plasma NRP-1, placenta growth factor (PlGF) and immune cell expression of the transcription factor <i>SNAI1</i> before and after NAC were significantly different. Paired <i>t-</i>test analysis of 22 locally advanced breast cancer patients showed that plasma NRP-1 levels were increased significantly (<i>p</i> = 0.018) post-NAC in patients with pathological partial response (pPR). …”
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FoxP3<sup>+</sup> T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets
Published 2020“…We also describe potential therapeutic strategies to target Tregs in combination with other types of immunotherapies aiming to overcome tumor resistance and improve clinical outcomes in cancer patients. Overall, understanding the prognostic significance of FoxP3<sup>+</sup> Tregs in various cancers and their contribution to therapy resistance could help in the development of more effective targeted therapeutic strategies to enhance the clinical outcomes in cancer patients.…”
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The downside of cardiac devices insertion
Published 2015“…“If TR is indeed shown to increase following lead implantation post-pacemaker insertion, and if in some patients the TR is severe and significantly affecting clinical symptoms, corrective surgery could be considered.”…”
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Complete resection of the alar folds in eight standing horses with a bipolar dividing and vessel‐sealing device
Published 2020“…</p> <h3>Clinical impact</h3> <p>This study describes a surgical technique offering a novel approach to resection of the alar folds in the standing horse.…”
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Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…Expression of CaM<sup>D132E</sup> and CaMD134H mutants results in significant reduction of the zebrafish heart rate, mimicking a severe form of human bradycardia, whereas expression of CaM<sup>Q136P</sup> results in an increased heart rate mimicking human ventricular tachycardia. …”
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DiaNet v2 deep learning based method for diabetes diagnosis using retinal images
Published 2024“…<p dir="ltr">Diabetes mellitus (DM) is a prevalent chronic metabolic disorder linked to increased morbidity and mortality. With a significant portion of cases remaining undiagnosed, particularly in the Middle East North Africa (MENA) region, more accurate and accessible diagnostic methods are essential. …”
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National Ambulance Service’s Preparation for the FIFA World Cup Qatar 2022<sup>TM</sup>
Published 2024“…Additionally, there has been increased collaboration between all emergency services to ensure a seamless response during the WC. …”
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