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significant clusters » significant cause (Expand Search), significant changes (Expand Search), significant factors (Expand Search)
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significant clusters » significant cause (Expand Search), significant changes (Expand Search), significant factors (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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20661
SPSS data.
Published 2025“…</p><p>Conclusion</p><p>Stigma remains a pervasive condition closely related to increased psychological suffering, decreased self-esteem and lower tendencies to seek help. …”
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20662
<b>Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional </b><b><i>WFS1</i></b><b> varian...
Published 2025“…Pancreatic β cells obtained from patient-derived induced Pluripotent Stem Cells (iPSCs) carrying this <i>WFS1 </i>variant exhibited reduced insulin processing and impaired secretory granule maturation, as evidenced by proinsulin accumulation and decreased prohormone convertase PC1/3. Moreover, they exhibited dysregulated Ca<sup>2+</sup> fluxes due to altered transcription of Ca<sup>2+</sup>-related genes, including <i>CACNA1D</i>, and significantly reduced <i>SNAP25</i> levels, leading to uncoordinated oscillations and poor glucose responsiveness. …”
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20663
Data Sheet 1_Preoperative remote consultation for a green bariatric surgery: can telemedicine be safe for patients and sustainable for the environment?.pdf
Published 2025“…At one-year follow-up, the mean BMI decreased to 29 kg/m<sup>2</sup> (±3). In the revisional surgery group, percent excess weight loss reached 75.4% at one year.…”
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20664
Table 1_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf
Published 2025“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
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20665
Data Sheet 1_Silica nanoparticles alleviate cadmium toxicity to Pisum sativum L. seedling growth by remodeling carbon-nitrogen metabolism.docx
Published 2025“…<p>The increasing incidence of soil cadmium (Cd) pollution significantly hinders the sustainable development of agriculture and food security. …”
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20666
Data Sheet 1_Repeated biocide treatments cause changes to the microbiome of a food industry floor drain biofilm model.zip
Published 2025“…Analysis of the viable survivors using MALDI-TOF MS and the regrowing biofilms using 16S rRNA amplicon sequencing showed how the diversity of the biofilm decreased but without any change in biocide tolerance as seen in log reductions (CFU/cm<sup>2</sup>). …”
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20667
Table 5_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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20668
Model-derived results show increased social following in individuals with disrupted utility-based risky decision-making.
Published 2024“…<b>(d)</b> We tested a link between decreased utility-based risk processing (measured by negative log likelihood in Solo trials; −LL) and increased ω<sub>follow</sub>. …”
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20669
Table 7_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …”
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20670
Image 1_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.jpeg
Published 2025“…</p>Results<p>miR-17-5p expression was significantly elevated in M. avium–infected macrophages, as well as in serum and peripheral blood mononuclear cells (PBMCs) from TB patients. …”
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20671
Table 1_Relationships between rumen methanogens and fungal communities and their response to changes in alfalfa forms and starch in sheep diets.docx
Published 2025“…The relative abundance of Aspergillus in the AHLR diet was significantly higher than in the AS diets (P < 0.01), and the relative abundance of Occultifur and Meyerozyma were decreased in the AH diets than in the AS diets (P < 0.05). …”
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20672
Data Sheet 1_Efficacy and safety of anlotinib combined with 125I seed implantation for iodine-refractory thyroid cancer.docx
Published 2025“…Tumor volumes in all groups decreased after treatment, with the greatest reduction within 6 months in the combination group (p < 0.001). …”
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20673
Table 3_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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20674
<b>Enhanced Regulation of Carbon Emissions and DOM Transport by Cascade Reservoirs in the Upper Yellow River</b>
Published 2025“…Overall, the diffusion flux of CO2(FCO2) and CH4(FCH4) at the water–air interface in each reservoir area exceeded those in natural channels. FCO2 showed a decreasing trend along the flow direction, whereas FCH4 exhibited the opposite pattern. …”
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20675
High-throughput single-cell analysis reveals Omp38-specific monoclonal antibodies that protect against <i>Acinetobacter baumannii</i> infection
Published 2024“…Flow cytometry and ELISA confirmed that immune cell infiltration and cytokine production, respectively, decreased in a mouse model of sublethal <i>A. baumannii</i> infection. …”
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20676
Image 1_A four-gene signature identified by integrated transcriptomic analysis for differential diagnosis and prognosis of uterine smooth muscle tumors.pdf
Published 2025“…Moreover, survival analysis revealed the prognostic significance of this four-gene signature: high TOP2A with low ABLIM1, FHL5, and MAP3K8 expression correlated with decreased overall survival in ULMS, implicating their potential role as diagnostic and prognostic markers. …”
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20677
Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts
Published 2024“…In vivo studies showed that overall tumor metastasis decreased in 4T1 xenografts mice treated with MSN-PEG/TA 25 with a notable reduction in lung tumor metastasis. …”
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20678
Supplementary file 1_ZnO nanoparticles induce acute arrhythmia and heart failure in mice by disturbing cardiac ion channels.pdf
Published 2025“…Mechanistically, exposure to ZnO NPs did not significantly affect the IK1, but it markedly decreased I<sub>Na</sub> and I<sub>Ca−L</sub> currents, resulting in a reduced amplitude and shortened duration of the action potential in cardiomyocytes. …”
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20679
Image 6_Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation...
Published 2025“…This approach revealed substantial Baltic genetic components in early Slavic populations (57% in Slovakia/Slovenia) decreasing to 39%–51% in medieval Croatian samples. …”
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20680
ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer
Published 2025“…Genetic or chemical inhibition of ELOVL6 results in decreased proliferation and migration, accompanied by alterations in fatty acid elongation. …”