Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors حسب Noura Aldous (15429873)

"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"

Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv... حسب Abdoulaye Diane (14152749)

"…Interestingly, addition of Exendin-4 (50 nM) during the last 3 days of the differentiation significantly enhanced GSIS associated with increased expression of glucose-sensing apparatus genes (Glut2, G6P2C, GCK) and genes encoding mitochondrial oxidative phosphorylation machinery.…"

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss حسب Meritxell Espino Guarch (18810097)

Qatar’s immigrants at higher risk of diabetes حسب Nature Research (16552612)

"…The results, however, suggest that Qatar’s immigrant population has a significantly increased risk of having undiagnosed T2D, and that glycated haemoglobin levels could be a useful diagnostic tool for early detection of the disease. …"

Protection of Banks Customers in the UAE حسب AlAwadhi, Ghaith Alhaj

"…On the other hand, the identified barriers include increased competition, cultural shift, and variations in business models.…"
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Assessment of Inventory and Transportation Collaboration in a Logistics Marketplace حسب Shahid, Saif Mohammad

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Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model حسب Sahar Isa Da’as (18288880)

"…These knockout zebrafish displayed significant morphological heart alterations related to a significant decrease in ventricular and atrial diameters at systolic and diastolic states at the larval stages. …"

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death حسب Tohme, Sara

"…Scavenging ROS using NAC significantly decreases cell death but has minimal effect on autophagy activation, suggesting that the accumulation of ROS is downstream of autophagy activation but upstream of cell death. …"
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Noninvasive assessment of coronary flow reserve in the left anterior descending artery by transthoracic echocardiography before and after stenting حسب Tarcha, Walid

"…However, after stenting the mean CFR was significantly higher: 2.18 ± 0.55 (1.3–3.8), with P <0.01. …"
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Noninvasive Assessment of Coronary Flow Reserve in the Left Anterior Descending Artery by Transthoracic Echocardiography before and after Stenting حسب Ghanem, Georges

"…However, after stenting the mean CFR was significantly higher: 2.18 ± 0.55 (1.3–3.8), with P <0.01. …"
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Industrial Processes Performance Improvement using Six Sigma Principles and Tools حسب AlAwadhi, Alya

"…Printing and packaging industries are continuously facing fierce competition and the challenge of meeting increasing demands for higher quality products at economical costs. …"
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Growth hormone treatment modulates active ghrelin levels in rats حسب Haddad, Haytham

"…Genotropin treatment caused a dose dependent decrease in active ghrelin concentration in stomach, kidney and pancreas with a concomitant increase in plasma, and reaching significance at 20 and 100 µg/rat/day doses. …"
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Aorta deformation linked to heart disease حسب Nature Research (16552612)

"…They found that the mechanics of the aorta were altered, with the pulsatile change in aortic diameter, distention and elasticity of the aortic walls being significantly decreased, and aortic stiffness significantly increased, in HCM patients compared to the controls. …"

Longitudinal Study of Hypertensive Subjects With Type 2 Diabetes Mellitus حسب Bahous, Sola Aoun

"…Using cross-sectional regression models, a significant association was observed between higher education levels, lower levels of anxiety and depression, and reduced overall mortality in diabetic hypertensive subjects, while impaired renal function, a history of stroke and myocardial infarction, and increased alcohol and tobacco consumption were significantly associated with increased mortality. …"
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Voiding function improves under long-term testosterone treatment (TTh) in hypogonadal men, independent of prostate size حسب Aksam Yassin (14779204)

"…</p><h3>Results</h3><p dir="ltr">Prior to TTh interruption, it was observed that testosterone stimulation improved the men’s IPSS, AMS and post-voiding residual bladder volume, while their prostate volume significantly increased. During the TTh interruption, there was a significant worsening in these parameters, although the increase in prostate volume continued. …"

Effect of chronic and non-chronic moderate wine consumption upon rat lipoprotein profile in the blood. (c2002) حسب Slaiby, Rita

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Exploring Ultra-Processed Foods: Impact on Satiety, Eating Patterns, Blood Glucose Levels and Food Addiction حسب Mamo, Tracy G.

"…Characterized by hyper-palatable ingredients and extensive processing, UPFs contribute to increased caloric intake, impaired satiety signals, and a higher prevalence of addictive-like eating behaviors. …"
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The development of psychological and associated mental health disorders after road traffic crashes and other injuries حسب Anthony Joseph (3383735)

"…It appears that up to 33% of patients may develop a psychiatric illness after a traumatic injury and this may lead to significant functional impairment and social dysfunction. …"

Triple therapy with pravastatin, low molecular weight heparin and low dose aspirin improves placental haemodynamics and pregnancy outcomes in obstetric antiphospholipid syndrome in... حسب Eleftheria Lefkou (17052414)

"…</p><h3>Conclusion</h3><p dir="ltr">LMWH + LDA + PRAV increased serum NO levels and significantly improved placental haemodynamics and maternal and neonatal outcomes in women and mice with OAPS. …"

Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 حسب Ramada R. Khaswaneh (22224544)

"…</p><h3>Results</h3><p dir="ltr">Our results showed for the first time that severe hypoxia can significantly impair Factor H secretion and CD59 expression in MSCs. …"