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241
Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
Published 2025“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”
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242
A snapshot of current medical research: The notion of supply and demand
Published 2017“…Therefore, it is time to be more selective and innovative with our research in order to have a significant positive impact on healthcare services.…”
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243
Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study
Published 2025“…</p><h3>Results</h3><p dir="ltr">A slight decrease in incidence rates from 80.57 to 79 per 100,000 was observed, alongside a significant increase in mortality rates from 14.11 to 17.2 per 100,000. …”
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244
Geopolitical instability and environmental sustainability
Published 2025“…Geopolitical instability significantly impacts environmental sustainability, yet its role remains underexplored. …”
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245
Wave-packet dynamics in monolayer graphene with periodic scattering potentials
Published 2025“…We found that, despite the pronounced Klein <u>tunneling</u> effect in graphene, the presence of a lattice of defects significantly impacts the propagation properties of the wave packets. …”
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246
CFD modeling of particle settling in drilling fluids: Impact of fluid rheology and particle characteristics
Published 2021“…Ellipsoidal cuttings exhibited significantly greater resistance to settling as compared to spherical particles, mainly due to the increased drag force. …”
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247
Coevolving residues distant from the ligand binding site are involved in GAF domain function
Published 2025“…Mutational incorporation into a Bioluminescence Resonance Energy Transfer (BRET)-based biosensors, which detects ligand-induced conformational changes, showed altered GAF domain conformation and increased EC50 for cGMP-induced conformational changes. …”
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248
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249
Breast Density Estimation in Mammograms Using Unsupervised Image Segmentation
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250
Circular economy application for a Green Stadium construction towards sustainable FIFA world cup Qatar 2022™
Published 2021“…<p dir="ltr">The construction industry is responsible for a significant amount of raw material consumption and environmental footprints. …”
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251
3D Printable Ca(OH)<sub>2</sub>-based geopolymer concrete with steel fiber reinforcement
Published 2025“…Durability assessments, including autogenous shrinkage and self-induced stress, indicated a slight reduction in shrinkage of SF-reinforced samples, with no significant effect on self-induced stress. Microstructural analysis using scanning electron microscopy (SEM) and X-ray micro-computed tomography (µCT) demonstrated the crack-bridging behavior of steel fibers, enhancing ductility and fracture resistance. …”
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252
Allelopathic Effects of the Invasive Prosopis juliflora (Sw.) DC. on Native Plants: Perspectives toward Agrosystems
Published 2023“…The seed radicle lengths at 2 mg mL−1 were significantly reduced for both plant species. The seed germination and radicle length of S. aegyptica and H. perfoliata were significantly decreased at 2 mg mL−1 of extract of P. juliflora. …”
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253
Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
Published 2020“…Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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254
Causes of Delay in Construction Projects in Oil and Gas Construction Industry
Published 2017“…The aim of the study was to establish the major causes of delay in the oil and gas construction projects and to group them in accordance with their importance and impacts. Qualitative method was used in a single case study adopted. …”
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255
Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages
Published 2020“…We found high levels of granulocytic myeloid cells (GMCs) in whole blood, but their levels were significantly lower in PBMCs. Importantly, we found significantly higher levels of GMCs in the TME compared to NT. …”
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256
Calculation of Average Road Speed Based on Car-to-Car Messaging
Published 2019“…It needs to be accomplished near GPS stream data sources to reduce latency and increase the accuracy of reporting. Solutions based on geo-distributed road monitoring, using Fog-computing paradigm, provide lower latency and higher accuracy than centralized (cloud-based) approaches. …”
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257
Trade Flow and Nation Brand Distance: A Structural Gravity Model Approach
Published 2021“…The empirical findings shows that NBD influence both export and import volume in which less distant countries in term of nation brands are able to overcome the negative effect of geographical distance which can stimulates the export mainly and import flow to some extent. The results on the impact of NBD on FTA and trade flows provides some interesting insights as the there is a negative and significant moderation impact of NBD on the relationship between FTA and both export and import volume which suggest that a decrease of NBD will increase the effect of FTA on trade flow. …”
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258
Use of Ultrasound and Ionic Liquids to Enhance the Extractive Desulfurization of Oils
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doctoralThesis -
259
A Novel Connection Setup Management Approach for Optical WDM Networks
Published 2007“…Wavelength Division Multiplexing (WDM) has significantly increased the transmission capacity of today's optical networks. …”
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260
Formation of Trihalomethanes during Seawater Chlorination
Published 2010“…<p dir="ltr">The use of seawater for industrial cooling is a vital technology that poses some of the most profound environmental impact on the water quality in the Arabian Gulf. Biocide (chlorine) is added to the seawater to control biofouling of the cooling system. …”