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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Moments-based computation of intermodulation distortion of RF circuits
منشور في 2001"…However, obtaining the IP3 using traditional harmonic balance simulation requires multitone inputs, which significantly increases the computational costs. On the other hand, analytical approaches based on obtaining closed-form expressions for Volterra functional series are too complex to be fully automated for arbitrary circuit topologies. …"
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Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients
منشور في 2016"…<p dir="ltr">Increased levels of myeloid cells, especially myeloid-derived suppressor cells (MDSCs), have been reported to correlate with bad prognosis and reduced survival in cancer patients. …"
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Exercise training-induced speeding of VO<sub>2 </sub>kinetics is not intensity domain-specific or correlated with indices of exercise performance
منشور في 2024"…There were no PRE to POST differences for CON (p < 0.05) in any variables. Despite significant increases in maximal VO<sub>2</sub> (VO<sub>2max</sub> ), estimated lactate threshold (θLT), maximal metabolic steady state (MMSS), and peak power output (PPO) for the intervention groups (p < 0.05), there were no significant correlations from PRE to MID or MID to POST between ΔτVO<sub>2</sub> and Δ V O<sub>2max</sub> (r=– 0.221, r = 0.119), ΔPPO (r= – 0.112, r= – 0.017), ΔθLT (r= 0.083, r = 0.142) and ΔMMSS (r= – 0.213, r = 0.049)(p > 0.05).…"
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Autism spectrum disorder in Qatar: Profiles and correlates of a large clinical sample
منشور في 2017"…<p dir="ltr">Autism spectrum disorder (ASD) is an increasingly prevalent disorder. Although around 15% of cases are caused by specific genetic causes, most cases involve a complex and variable combination of genetic risk and environmental factors that are not yet identified. …"
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Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline
منشور في 2020"…Here, we used bisulfite pyrosequencing and show that methylation of the rDNA transcription unit including upstream control element (UCE), core promoter, 18S rDNA, and 28S rDNA in human sperm also significantly increases with donor's age. This positive correlation between sperm rDNA methylation and biological age is evolutionarily conserved among mammals with widely different life spans such as humans, marmoset, bovine, and mouse. …"
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Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease
منشور في 2017"…CSF total α-syn (t-α-syn) significantly increased in the AD group (p < 0.0001) compared to controls, while oligomeric- and phosphorylated-Ser129-α-syn did not change significantly. …"
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Systematic analysis of software development in cloud computing perceptions
منشور في 2023"…<p></p><div> <p>Cloud computing is characterized as a shared computing and communication infrastructure. …"
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Correlating process parameters to thrust forces and torque in the friction stir processing of AZ31B
منشور في 2014"…The thrust force and torque exhibited opposite trends with increasing tool rotational speed. The thrust force increased while the torque decreased as the tool rotational speed increased. …"
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Correlations between Resting Electrocardiogram Findings and Disease Profiles: Insights from the Qatar Biobank Cohort
منشور في 2024"…Elevated QTc was observed in CAD patients, whereas decreased QTc was correlated with decreased levels of calcium and potassium. …"
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Dietary Calcium Intake of 1200 mg/d May Have Negative Correlation on Percent Body Fat
منشور في 2006"…Calcium intake was not statistically correlated with body composition. The high-calcium group (intake ≥1200 mg/d) had a significantly higher mean caloric intake (P ≤ .01) and significantly lower percent body fat (P ≤ .05) than the low-calcium group (intake <1200 mg/d). …"
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An overview of Information and Computer Technology Ethics in the United Arab Emirates
منشور في 2009"…The UAE as a young and quickly rising nation has undergone a fast transformation in a relatively short span of time into a financial, industrial, tourist and strategic hub of the region. With the increasing significance of information and computer technology and the associated risks, it is important to gain insight into both the ethical environment as a whole, and specifically where it applies to information and computer technology. …"
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Prevalence, correlates and management of hyperglycemia in diabetic non-critically Ill patients at a tertiary care center in Lebanon
منشور في 2019"…Episodes of hyperglycemia in hospitalized diabetic patients are associated with poor clinical outcomes and increased morbidity and mortality. Therefore, prevention of hyperglycemia is critical to decrease the length of hospital stay and to reduce complications and readmissions. …"
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Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains
منشور في 1991"…Decreased striatal dopamine levels in these latter rat strains were associated with increased dopamine turnover. …"
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SVM-based task admission control and computation offloading using lyapunov optimization in heterogeneous MEC network
منشور في 2022"…Results demonstrate high performance gains of the proposed solution that employs SVM-based task admission and Lyapunov-based computation offloading strategies. Significant increase in number of completed tasks, energy savings, and cost reductions are resulted as compared to alternative baseline approaches.…"
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Cloud providers collaboration for a higher service level in cloud computing
منشور في 2013"…Cloud computing is increasingly becoming a desirable and foundational element in international enterprise computing. …"
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