Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... حسب Mohamed Yassin (4166515)

"…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …"

SYSTEM DYNAMICS APPROACH FOR WHOLE LIFE CYCLE COST MODELLING OF RESIDENTIAL BUILDING PROJECTS IN UNITED ARAB EMIRATES حسب Sadek, Ahmed

"…This is achieved by applying adjusting risks on project's initial cost at the preconstruction stage with respect to cost and risk behaviours at each time step. Cost impact is following an increasing S-Curve behaviour during CAPEX time and risk impact is following a decreasing S-Curve behaviour during CAPEX lifetime. …"
احصل على النص الكامل

Essays on the effect of excess compensation and governance changes on firm value حسب Dah, Mustafa A.

"…Furthermore, although director excess compensation is not significantly inversely related to the firm’s future performance, it has an indirect negative effect on future performance through its impact on the entrenchment performance relationship. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels حسب Haya Al-Sulaiti (5449256)

"…Results indicate that AuNPs treatment significantly impacted several metabolic pathways. Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. …"

Prevalence of bullying and violence among adolescents in Arab Gulf countries: a systematic review حسب Amani N. Alansari (19743643)

"…Academic impacts included increased absenteeism (24–29%) and decreased performance.…"

Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub... حسب SUGATHAN, SANAL

"…The outcome of these events, abundant regional solar irradiation and drop in global PV prices has led to the significant developments and innovations in the solar energy sector. …"
احصل على النص الكامل

Does Ultrasound Really Good Enough to Evaluate the Pneumothorax in the Emergency Department حسب Atilla Temel (17788481)

"…Thorax ultrasonography is a useful technique with high specificity in diagnosing pneumothorax, but its sensitivity decreases significantly when the size is below 1 cm.…"

Revealing the Adoption Factors of Electric Vehicles in Dubai حسب BIN HUMAID, HUDA

"…Surprisingly, the research fails to provide enough evidence to prove the claim that the sufficient availability of charging infrastructure has a positive impact on the willingness to adopt EVs. This research provides significant insights into the dynamics of EV adoption in Dubai. …"
احصل على النص الكامل

A snapshot of current medical research: The notion of supply and demand حسب Almutairi, Adel F.

"…Therefore, it is time to be more selective and innovative with our research in order to have a significant positive impact on healthcare services.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Allelopathic Effects of the Invasive Prosopis juliflora (Sw.) DC. on Native Plants: Perspectives toward Agrosystems حسب Shazia Bibi (16500318)

"…The seed radicle lengths at 2 mg mL−1 were significantly reduced for both plant species. The seed germination and radicle length of S. aegyptica and H. perfoliata were significantly decreased at 2 mg mL−1 of extract of P. juliflora. …"

Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages حسب Salman M. Toor (8854751)

"…We found high levels of granulocytic myeloid cells (GMCs) in whole blood, but their levels were significantly lower in PBMCs. Importantly, we found significantly higher levels of GMCs in the TME compared to NT. …"

Unsustainability in emergent systems حسب Haddad, Marc

"…These challenges are already significant enough to seriously hamper the network's ability to deliver an acceptable level of service within reasonable norms for environmental, health and safety impacts, especially in and around the country's major urban centers. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Formation of Trihalomethanes during Seawater Chlorination حسب Ahmed Abdel-Wahab (1748986)

"…Chlorination of seawater has shown significant increase in total THMs (TTHMs) and in bromoform concentrations. …"

Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic حسب Turki, O.

"…We report the impact of dysprosium (Dy, with y = 0.01, 0.02, 0.05 and 0.08) substitution in (Na0.5 Bi0.5)0.94 Ba0.06TiO3 (NBT-6BT) lead-free ceramics. …"
احصل على النص الكامل

Developing a Stochastic Model to Predict Cost Overrun due to the Causes of Projects Delay in Oil Fields Construction Industry حسب ALKHOORI, KHALID ABDUL MAJEED

"…The research results revealed that poor contractor works was found to have the most significant positive impact in the delay experienced by the projects considered in this work. …"
احصل على النص الكامل

Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers حسب Yadav, Santosh K.

"…ResultsHIC and HUC groups showed significantly decreased NP test scores in various domain compared to CHNM. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy حسب Taki, Fatima

"…Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens حسب Sheraz Ahmed Bhatti (9759633)

"…Dietary OTA at all the tested levels induced the hepatic and renal tissue injury as indicated by significant decreased total antioxidant capacity in these organs along with significant decreased (p ≤ 0.05) serum concentrations of total proteins and albumin. …"

Optimizing the Cleaning Frequency of Solar Photovoltaic (PV) systems Using Numerical Analysis حسب Kaiss, El-Cheikh Amer Kais

احصل على النص الكامل

Assessment of Brain Function After 240 Days Confinement Using Functional Near Infrared Spectroscopy حسب Yahya, Fares

"…The FCN shows a significant decrease in most of the right frontal areas. …"
احصل على النص الكامل