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17361
Supplementary Tables 1-7 from Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer
Published 2025“…<p>Table S1: List of top 20 significant (p< 0.05) genes from a whole-genome CRISPRi FACS-based screen which increased or decreased MHC Class I expression upon knockdown. …”
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17362
Data Sheet 1_Splenic volume as a predictor of survival in cancer patients treated with immune checkpoint inhibitors.docx
Published 2025“…Additionally, HCC patients who experienced an increase in spleen volume during ICI therapy exhibited significantly poorer OS (HR: 2.27, 95% CI: 1.17–4.41, p = 0.016) and PFS (HR: 2.40, 95% CI: 1.30–4.41, p = 0.005) than those whose spleen volume decreased. …”
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17363
Inference of cell-type proportions from bulk RNAseq and dynamics during myocardial infarction in α1A-AR-KO mice.
Published 2025“…<b>(D)</b> Estimation of cardiac cell type composition changes post-myocardial infarction (MI) and in α1A-AR knockout (cmAKO) mice, showing increased proportions of macrophages and fibroblasts and decreased proportions of cardiomyocytes, with more pronounced changes in cmAKO mice. …”
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17364
Table 3_Tick HRF-dependent ferroptosis pathway to promote tick acquisition of Babesia microti.xlsx
Published 2025“…The midgut divalent iron (p<0.01) and reactive oxygen species (ROS) (p<0.05) levels were significantly elevated in infected ticks, and transmission electron microscopy (TEM) showed that mitochondrial ridges were absent or decreased in size. …”
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17365
Table 1_Tick HRF-dependent ferroptosis pathway to promote tick acquisition of Babesia microti.docx
Published 2025“…The midgut divalent iron (p<0.01) and reactive oxygen species (ROS) (p<0.05) levels were significantly elevated in infected ticks, and transmission electron microscopy (TEM) showed that mitochondrial ridges were absent or decreased in size. …”
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17366
Table 2_Tick HRF-dependent ferroptosis pathway to promote tick acquisition of Babesia microti.docx
Published 2025“…The midgut divalent iron (p<0.01) and reactive oxygen species (ROS) (p<0.05) levels were significantly elevated in infected ticks, and transmission electron microscopy (TEM) showed that mitochondrial ridges were absent or decreased in size. …”
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17367
Data Sheet 1_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont...
Published 2025“…Adding TXL to WM showed a non-significant trend toward reducing myocardial infarction [RR 0.34, 95% CI (0.05, 2.12); NNT = 41] and sudden cardiac death [RR 0.34, 95% CI (0.01, 8.28); NNT = 65]. …”
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17368
Data Sheet 3_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.docx
Published 2025“…ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”
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17369
Image 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..tif
Published 2025“…The polyphenolic composition of the two cultivars significantly changed depending on the type of LEDs used. …”
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17370
Data Sheet 1_Global burden of disease among adolescents and young adults with drug use disorders, 1990–2021: based on GBD 2021.doc
Published 2025“…Additionally, gender plays a significant role in the distribution of this burden, with males experiencing a higher burden than females. …”
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17371
Data Sheet 2_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf
Published 2025“…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
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17372
Data Sheet 1_Comparative analysis of proteomics and transcriptomics reveals novel mechanism underlying the antibacterial activity and immune-enhancing properties of horse milk.zip
Published 2025“…Further transcriptome analysis demonstrated that PGL exerted significant transcriptional changes to bacteria. Enrichment analysis showed PGL could inhibit growth of P. aeruginosa and E. coli by repressing the biosynthesis of secondary metabolites.…”
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17373
Table 4_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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17374
Image 1_iPSC-derived exosomes as amphotericin B carriers: a promising approach to combat cryptococcal meningitis.tif
Published 2025“…Background<p>Cryptococcal meningitis (CM) is a significant global health issue, particularly affecting individuals with HIV. …”
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17375
Data Sheet 1_Global burden and trend of stroke attributable to metabolic risks among young adults (20–39 years old) from 1990 to 2021.docx
Published 2025“…From 1990 to 2021, the absolute number of stroke-related DALYs attributable to metabolic-risks increased by 22.23%, while the ASDR decreased by 0.78% annually. Regional disparities were evident, with East Asia reporting the largest number of stroke-DALYs attributable to metabolic-risks and Southeast Asia exhibiting the highest ASDR. …”
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17376
Focus group guide.
Published 2025“…<div><p>Amid the dismantling of state structures in Haiti, the first Black republic faces significant health disparities compared to its former colonial power, France. …”
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17377
Table 6_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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17378
Evaluation results.
Published 2024“…It focuses on identifying and quantifying clinically significant materials in the presence of metal objects. …”
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17379
Data Sheet 1_Lung microbiome alterations correlate with immune imbalance in non-small cell lung cancer.docx
Published 2025“…Furthermore, patients with higher abundance of Prevotella and Veillonella exhibited a significantly elevated systemic immune-inflammation index (SII) compared to the lower-abundance group (P = 0.0329), while their CD8<sup>+</sup> T cell levels were significantly decreased in the higher abundance group (P = 0.0027).…”
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17380
Data Sheet 1_Based on bioinformatics, SESN2 negatively regulates ferroptosis induced by ischemia reperfusion via the System Xc−/GPX4 pathway.csv
Published 2025“…Spearman’s correlation analysis revealed a significant correlation between the hub genes and ferroptosis-related DEGs. …”