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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…Finally, as a definitive and specific way to modulate SLFN11 expression we implemented SLFN11 dCas9 (dead CRISPR associated protein 9) systems to specifically increase or decrease SLFN11 expression.…”
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The differential impact of IFRS adoption on aspects of seasoned equity offerings in the UK and France
Published 2018“…Accordingly, we find that, following IFRS adoption, earnings management activities decrease among high-divergence firms prior to issuing SEOs. …”
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Symptoms of depression and anxiety in anorexia nervosa
Published 2014“…We speculate that enhanced TRP availability during re-feeding, as a result of the increase in the TRP/LNAA ratio, could restore serotonin neurotransmission and lead to a decrease in depressive symptoms. …”
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Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study
Published 2021“…The differences in mean scores for all psychological and coping strategies used among participants across the 3 levels of vulnerability to SARS-CoV-2 were statistically significant. …”
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A Multidecadal Assessment of Haze Development and Fluctuations in Visibility for Arabian Peninsula
Published 2024“…To comprehend the time-based patterns of visibility across the ME, we utilized the Mann Kendall (MK) and Modified Mann Kendall (MMK) trend estimators in both space and time. …”
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Acute intense fatigue does not modify the effect of EVA and TPU custom foot orthoses on running mechanics, running economy and perceived comfort
Published 2022“…There was a global fatigue-induced deterioration in running economy (− 1.6 ± 0.4%; P < 0.001). There was no significant condition × fatigue [except mean loading rate (P = 0.046)] for the large majority of biomechanical, cardio-respiratory [except minute ventilation (P = 0.020) and breathing frequency (P = 0.019)] and perceived comfort variables. …”
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Prehospital plasma transfusion versus standard of care following traumatic injury: a review of the systematic reviews and a meta-analysis
Published 2025“…PHP did not significantly decrease vasopressor use or late mortality; however, it may reduce the total use of RBCs in the first 24 h. …”
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Transfer function analysis between arterial pressure and renal sympathetic nerve activity at cardiac pacing frequencies in the rat
Published 2007“…Cardiac pacing slightly increased mean AP (0.8 ± 0.2 mmHg/Hz) and decreased pulse pressure (−3.6 ± 0.3 mmHg/Hz) while leaving the mean level of RSNA essentially unaltered (P = 0.680, repeated-measures ANOVA). …”
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Seasonal variation, polymer hazard risk and controlling factors of microplastics in beach sediments along the southeast coast of India
Published 2022“…<p>Microplastics (MPs) and its associated organic and inorganic contaminants are one among the significant health hazards to almost all biota, including human. …”
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The downsides of information systems security policy compliance efforts
Published 2016“…Modern organizations face significant information security violations from inside the organizations to which they respond with various managerial techniques. …”
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Second-law-based performance evaluation of cooling towers and evaporative heat exchangers
Published 2020“…For the different input variables investigated, efficiencies were, almost always, seen to increase or decrease monotonically. We notice that an increase in the inlet wet bulb temperature invariably increases the second-law efficiency of all the heat exchangers. …”
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Effect of Mg incorporation on the properties of PCL/Mg composites for potential tissue engineering applications
Published 2024“…However, the elastic modulus decreased by around 50% for the same composition. The thermal study revealed a significant reduction in the degradation temperature from above 400°C for pure PCL to around 300°C for PCL/Mg composite having 15% Mg. …”
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Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis
Published 2023“…<h3>Background</h3><p dir="ltr">The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. …”
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Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review
Published 2024“…During the first year of the pandemic, Lebanon implemented multiple lockdowns during which SHS endured repetitive closures. We explore the impact of the pandemic on SHS delivery and the diagnosis rate of sexually transmitted infections (STIs) among attendees of a large sexual health clinic in Beirut, Lebanon. …”
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