Showing 21 - 40 results of 19,421 for search '(( significant decrease based ) OR ( significant ((nn decrease) OR (teer decrease)) ))', query time: 1.16s Refine Results
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    Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx by Stefanie Hoffmann (3756733)

    Published 2025
    “…Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…”
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    Oxidative Nickel-Catalyzed <i>ortho</i>-C–H Amination of (Iso)quinolines with Alicyclic Amines Directed by a Sacrificial <i>N</i>‑Oxide Group by Weiqi Zhu (17845973)

    Published 2024
    “…Transition metal (TM)-catalyzed direct amination of C–H bonds on free or fused pyridine (Py) rings with free amines still remains scarce because amines and the Py ring tend to adopt a nonproductive N-bound coordination with many TMs, leading to a significant decrease of catalytic reactivity. We herein disclose a nickel-catalyzed and a sacrificial <i>N</i>-oxide group directed oxidative coupling of (iso)quinolyl C–H bonds and alicyclic amines, which furnishes bioimportant amino(iso)quinolines efficiently and selectively in a single step. …”
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    Y-27632 collaborated with BA to attenuate the increase in the integrity and decrease in the permeability of epithelial barrier injury induced by LPS in Caco2 monolayers. by Luqiong Liu (11537092)

    Published 2024
    “…<p>(<b>A)</b> Y-27632 collaborated with BA to attenuate the effect of LPS on TEER in Caco2 cells on days 1–22. (<b>B)</b> Y-27632 collaborated with BA to attenuate the effect of LPS on TEER in Caco2 cells on day 22. …”
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