Showing 141 - 160 results of 22,989 for search '(( significant decrease based ) OR ( significant small decrease ))', query time: 0.47s Refine Results
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    Discovery of Small Molecules Simultaneously Targeting NAD(P)H:Quinone Oxidoreductase 1 and Nicotinamide Phosphoribosyltransferase: Treatment of Drug-Resistant Non-small-Cell Lung C... by Kuojun Zhang (10339222)

    Published 2022
    “…Inspired by the synergistic antitumor effect between NAD­(P)­H:quinone oxidoreductase 1 (NQO1) substrates increasing the NAD consumption and nicotinamide phosphoribosyltransferase (NAMPT) inhibitors hampering the NAD synthesis, first-in-class small molecules simultaneously targeting NQO1 and NAMPT were identified through structure-based design. …”
  11. 151

    Discovery of Small Molecules Simultaneously Targeting NAD(P)H:Quinone Oxidoreductase 1 and Nicotinamide Phosphoribosyltransferase: Treatment of Drug-Resistant Non-small-Cell Lung C... by Kuojun Zhang (10339222)

    Published 2022
    “…Inspired by the synergistic antitumor effect between NAD­(P)­H:quinone oxidoreductase 1 (NQO1) substrates increasing the NAD consumption and nicotinamide phosphoribosyltransferase (NAMPT) inhibitors hampering the NAD synthesis, first-in-class small molecules simultaneously targeting NQO1 and NAMPT were identified through structure-based design. …”
  12. 152

    Discovery of Small Molecules Simultaneously Targeting NAD(P)H:Quinone Oxidoreductase 1 and Nicotinamide Phosphoribosyltransferase: Treatment of Drug-Resistant Non-small-Cell Lung C... by Kuojun Zhang (10339222)

    Published 2022
    “…Inspired by the synergistic antitumor effect between NAD­(P)­H:quinone oxidoreductase 1 (NQO1) substrates increasing the NAD consumption and nicotinamide phosphoribosyltransferase (NAMPT) inhibitors hampering the NAD synthesis, first-in-class small molecules simultaneously targeting NQO1 and NAMPT were identified through structure-based design. …”
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    Fig 9 - by Yi-xiao Liu (14769126)

    Published 2023
    Subjects: