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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
changes decrease » larger decrease (Expand Search), change increases (Expand Search), largest decrease (Expand Search)
decrease cell » decreased cell (Expand Search), increased cell (Expand Search), disease cell (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
changes decrease » larger decrease (Expand Search), change increases (Expand Search), largest decrease (Expand Search)
decrease cell » decreased cell (Expand Search), increased cell (Expand Search), disease cell (Expand Search)
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siRNA-based knockdown of <i>CLU</i> results in decreased VWF and CLU protein expression but no change in <i>VWF</i> mRNA content.
Published 2024“…As expected, VWF siRNA knockdown has no effect on <i>CLU</i> expression (2A). qPCR analysis of <i>VWF</i> expression demonstrates no significant decrease in <i>VWF</i> expression in <i>CLU</i> siRNA-transfected cells but expected <i>VWF</i> knockdown in <i>VWF</i> siRNA-transfected cells as compared to control siRNA (2B). …”
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CRISPR-Cas9 knockout of <i>CLU</i> results in decreased VWF protein expression VWF mRNA.
Published 2024“…<p>A CRISPR-Cas9 knockout HUVEC cell line (<i>CLU</i><sup><i>KO</i></sup>) demonstrated significant decreases in <i>CLU</i> expression as measured by PCR compared to a mock/control CRISPR-Cas9 HUVEC cell line (2A). …”
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MAMDC4 deletion decreases cell proliferation and YAP nuclear localization.
Published 2024“…<p>(A) CRISPR/Cas9 Caco2<sub>BBE</sub> control and MAMDC4 KO cells were grown on coverslips for 48 hours and labeled with antibodies against pHH3 and counterstained with DAPI. pHH3 positive cells were quantified by immunofluorescence. pHH3 labeling is decreased after MAMDC4 KO, and MAMDC4 overexpression rescues the proliferation phenotype. 500 to 1000 cells were counted for each experimental condition (n = 3). …”
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