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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
decrease cgas » increased cgas (Expand Search), increases cgas (Expand Search)
degs decrease » mean decrease (Expand Search), we decrease (Expand Search), deaths decreased (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
decrease cgas » increased cgas (Expand Search), increases cgas (Expand Search)
degs decrease » mean decrease (Expand Search), we decrease (Expand Search), deaths decreased (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
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Changes in TEER and permeability of EA.hy926 cells exposed to EVs or pellets from infected or uninfected macrophages.
Published 2020“…Interestingly, TEER increased significantly (up to 15 Ω/cm<sup>2</sup>) when EA.hy926 cells were exposed to EVs obtained from infected U937 macrophages (<i>EV (+)</i><sub><i>4G2</i></sub> or <i>P(+))</i> (B). …”
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Gene ontology (GO) term for DEGs.
Published 2025“…In addition, interference with <i>COL1A1</i> significantly inhibited the expression of <i>PLTP</i>, <i>ABHD6</i>, <i>LPIN1</i>, and <i>PTGS2</i> and decreased the levels of triglycerides and cholesterol at 4 and 8 days. …”
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Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx
Published 2025“…Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…”
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Data Sheet 2_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.pdf
Published 2025“…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”
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Data Sheet 1_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.zip
Published 2025“…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”