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Data Sheet 3_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf
Published 2025“…Background<p>Cyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. …”
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Data Sheet 1_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf
Published 2025“…Background<p>Cyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. …”
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Data Sheet 2_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf
Published 2025“…Background<p>Cyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. …”
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Data Sheet 2_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology...
Published 2025“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
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Data Sheet 3_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology...
Published 2025“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
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Data Sheet 1_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology...
Published 2025“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
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Data Sheet 2_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx
Published 2025“…</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …”
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Data Sheet 1_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx
Published 2025“…</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …”
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List of DEGs from neuronal cell analysis.
Published 2025“…We also identify hundreds of differentially expressed genes (DEGs) in iPSCs, NPs and CNs in KS1. In contrast with the epigenomic changes, the number of DEGs decrease as differentiation progresses. …”
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List of DEGs from iPSC analysis.
Published 2025“…We also identify hundreds of differentially expressed genes (DEGs) in iPSCs, NPs and CNs in KS1. In contrast with the epigenomic changes, the number of DEGs decrease as differentiation progresses. …”
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Mechanism of the Mixture of Abscisic Acid and Thidiazuron in Regulating Cotton Leaf Abscission
Published 2022“…A total of 2805 DEGs were detected after treatment with A, 18 849 DEGs after treatment with T, 29 822 DEGs after treatment with AT, and 26 446 DEGs after treatment with TD. …”
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Enrichment analysis of genes from the significant MS module.
Published 2025“…<p><b>(a)</b> Venn diagram showing the intersection of DEGs and significant module genes from WGCNA, resulting in 46 key intersection genes. …”
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Data_Sheet_1_Porphyromonas gingivalis induces an inflammatory response via the cGAS-STING signaling pathway in a periodontitis mouse model.PDF
Published 2023“…Furthermore, we report that a STING inhibitor (SN-011) significantly decreased inflammatory cytokine production and osteoclast formation in a periodontitis mouse model with P. gingivalis. …”
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Table_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.xlsx
Published 2022“…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
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Image_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif
Published 2022“…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”