يعرض 141 - 160 نتائج من 2,506 نتيجة بحث عن '(( significant decrease cgas ) OR ( significant ((i.e decrease) OR (teer decrease)) ))*', وقت الاستعلام: 0.36s تنقيح النتائج
  1. 141

    Table_6_Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.pdf حسب Joseph R. Podojil (12050717)

    منشور في 2022
    "…The present studies describe a novel use for ONP-302, employing an altered dosing scheme to reprogram myeloid cells resulting in significant enhancement of tumor immunity. ONP-302 infusion decreased tumor growth via the activation of the cGAS/STING pathway within myeloid cells, and subsequently increased NK cell activation via an IL-15-dependent mechanism. …"
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    Mutants of T6SS genes in <i>E</i>. <i>ictaluri</i>. حسب Safak Kalindamar (7478228)

    منشور في 2023
    "…These findings shed light on the role of the T6SS in <i>E</i>. <i>ictaluri</i> pathogenesis, highlighting its significance in intracellular survival, host cell attachment and invasion, stress resistance, and virulence. …"
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    FBW7 is degraded during <i>E</i>. <i>chaffeensis</i> infection. حسب Jennifer Y. Wang (8787527)

    منشور في 2020
    "…Significant decrease of FBW7 level was detected by 72 hpi compared to ctrl (<i>p</i><0.05). n = 4. …"
  14. 154

    Sustained-release of phages targets <i>E</i>. <i>faecalis</i> biofilm. حسب Mor Shlezinger (4897351)

    منشور في 2019
    "…<p><b>(A) <i>E</i>. <i>faecalis</i> biofilm biomass decreased following treatment with sustained-release EFDG1/EFLK1 phage cocktail.…"
  15. 155

    <i>Trans</i>-eQTL colocalized in Alzheimer’s disease associated CLU locus. حسب Satesh Ramdhani (8394399)

    منشور في 2020
    "…The minor and AD-protective allele rs9331896-C is associated with decreased (blue lines) and increased (red lines) expression of <i>trans</i>-eGenes. …"
  16. 156

    DataSheet1_Glycyrrhiza uralensis polysaccharides ameliorates cecal ligation and puncture-induced sepsis by inhibiting the cGAS-STING signaling pathway.zip حسب Siwen Hui (15141541)

    منشور في 2024
    "…</p><p>Results: GUP could effectively inhibit the activation of the cGAS-STING signaling pathway accompany by a decrease the expression of type I interferon-related genes and inflammatory factors in BMDMs, THP-1, and human PBMCs. …"
  17. 157

    Damage accumulation decreases elongation rates and displaces growth equilibrium. حسب Audrey Menegaz Proenca (845486)

    منشور في 2019
    "…<p>All panels depict MG1655 wild-type <i>E</i>. <i>coli</i>. (A) Exposure to phototoxic damage led to decreasing elongation rates in all treatment levels (length of exposure, every 2 min: 70 ms, 700 ms, 1 s, 1.5 s, 3 s). …"
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    Data acquired from testing the effect of PAR1 inhibitors on Plasmodium falciparum-induced loss of endothelial cell barrier function حسب Janet Storm (8266991)

    منشور في 2020
    "…The authors used a co-culture of primary human brain microvascular endothelial cells (HBMEC) with <i>Plasmodium falciparum</i> material, recombinant PfEMP1 or lysates from infected erythrocytes (IE), and measured barrier function by Trans Endothelial Electrical Resistance (TEER). A selection of Protease-Activated Receptor-1 (PAR1) inhibitors was tested for their ability to reverse the <i>P. falciparum</i> and thrombin induced decrease in barrier function.…"
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    Image_1_Extracellular vesicles from A23187-treated neutrophils cause cGAS-STING-dependent IL-6 production by macrophages.tif حسب Edwina R. Allen (13172643)

    منشور في 2022
    "…Given these unexpected results, we investigated whether macrophage mtDNA activated the cGAS-STING signaling axis. Consistent with mitochondrial outer membrane permeabilization (MOMP), a defined mechanism of mtDNA release, we observed macrophage mitochondrial membrane depolarization, a decrease in cytosolic Bax, and a decrease in mitochondrial cytochrome c, suggesting that macrophage mtDNA may initiate this EV-dependent signaling cascade. …"