Showing 41 - 60 results of 208 for search '(( significant decrease cgas ) OR ( significant ((nn decrease) OR (teer decrease)) ))', query time: 0.28s Refine Results
  1. 41

    Data Sheet 2_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

    Published 2025
    “…Background<p>Cyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. …”
  2. 42

    Data Sheet 2_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

    Published 2025
    “…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
  3. 43

    Data Sheet 3_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

    Published 2025
    “…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
  4. 44

    Data Sheet 1_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

    Published 2025
    “…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
  5. 45

    Data Sheet 2_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx by Xin Zhou (54275)

    Published 2025
    “…</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …”
  6. 46

    Data Sheet 1_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx by Xin Zhou (54275)

    Published 2025
    “…</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …”
  7. 47

    Data_Sheet_1_Porphyromonas gingivalis induces an inflammatory response via the cGAS-STING signaling pathway in a periodontitis mouse model.PDF by Rong Bi (8764434)

    Published 2023
    “…Furthermore, we report that a STING inhibitor (SN-011) significantly decreased inflammatory cytokine production and osteoclast formation in a periodontitis mouse model with P. gingivalis. …”
  8. 48

    Table_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.xlsx by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
  9. 49

    Image_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
  10. 50

    Image_10_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
  11. 51

    Image_9_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
  12. 52

    Image_3_cGAS/STING and innate brain inflammation following acute high-fat feeding.jpeg by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
  13. 53

    Image_2_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
  14. 54

    Image_8_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
  15. 55

    Image_7_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
  16. 56

    Image_4_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
  17. 57

    Image_6_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
  18. 58

    Image_5_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
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