بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
decrease cgas » increased cgas (توسيع البحث), increases cgas (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
nn decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
decrease cgas » increased cgas (توسيع البحث), increases cgas (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
nn decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
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Oxidative Nickel-Catalyzed <i>ortho</i>-C–H Amination of (Iso)quinolines with Alicyclic Amines Directed by a Sacrificial <i>N</i>‑Oxide Group
منشور في 2024"…Transition metal (TM)-catalyzed direct amination of C–H bonds on free or fused pyridine (Py) rings with free amines still remains scarce because amines and the Py ring tend to adopt a nonproductive N-bound coordination with many TMs, leading to a significant decrease of catalytic reactivity. We herein disclose a nickel-catalyzed and a sacrificial <i>N</i>-oxide group directed oxidative coupling of (iso)quinolyl C–H bonds and alicyclic amines, which furnishes bioimportant amino(iso)quinolines efficiently and selectively in a single step. …"
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Data Sheet 3_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf
منشور في 2025"…HT1080 cells, three-dimensional (3D) spheroids, and the xenograft mouse models were treated with IFNβ, RSL3, or IFNβ combination with RSL3 to analyze whether IFNβ enhances RSL3-induced ferroptosis.</p>Results<p>Here, we found that IFNβ could promote intracellular Fe<sup>2+</sup> and lipid peroxidation levels, and decrease GSH levels in tumor cells. …"
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Data Sheet 1_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf
منشور في 2025"…HT1080 cells, three-dimensional (3D) spheroids, and the xenograft mouse models were treated with IFNβ, RSL3, or IFNβ combination with RSL3 to analyze whether IFNβ enhances RSL3-induced ferroptosis.</p>Results<p>Here, we found that IFNβ could promote intracellular Fe<sup>2+</sup> and lipid peroxidation levels, and decrease GSH levels in tumor cells. …"
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Data Sheet 2_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf
منشور في 2025"…HT1080 cells, three-dimensional (3D) spheroids, and the xenograft mouse models were treated with IFNβ, RSL3, or IFNβ combination with RSL3 to analyze whether IFNβ enhances RSL3-induced ferroptosis.</p>Results<p>Here, we found that IFNβ could promote intracellular Fe<sup>2+</sup> and lipid peroxidation levels, and decrease GSH levels in tumor cells. …"
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Data Sheet 2_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.pdf
منشور في 2025"…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …"