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Showing 21 - 40 results of 61 for search '(( significant decrease cgas ) OR ( significant a decrease ))~', query time: 0.67s Refine Results
  1. 21
    Image_1_Extracellular vesicles from A23187-treated neutrophils cause cGAS-STING-dependent IL-6 production by macrophages.tif

    Image_1_Extracellular vesicles from A23187-treated neutrophils cause cGAS-STING-dependent IL-6 production by macrophages.tif by Edwina R. Allen (13172643)

    Published 2022
    “…Given these unexpected results, we investigated whether macrophage mtDNA activated the cGAS-STING signaling axis. Consistent with mitochondrial outer membrane permeabilization (MOMP), a defined mechanism of mtDNA release, we observed macrophage mitochondrial membrane depolarization, a decrease in cytosolic Bax, and a decrease in mitochondrial cytochrome c, suggesting that macrophage mtDNA may initiate this EV-dependent signaling cascade. …”
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  2. 22
    MeV induced RIG-I pathway <i>via</i> RNA polymerase III.

    MeV induced RIG-I pathway <i>via</i> RNA polymerase III. by Pierre Khalfi (7868252)

    Published 2023
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  3. 23
    Image_1_The cGAS/STING–TBK1–IRF Regulatory Axis Orchestrates a Primitive Interferon-Like Antiviral Mechanism in Oyster.jpeg

    Image_1_The cGAS/STING–TBK1–IRF Regulatory Axis Orchestrates a Primitive Interferon-Like Antiviral Mechanism in Oyster.jpeg by Xue Qiao (1409857)

    Published 2021
    “…These results indicated that there was a primitive IFN-like antiviral mechanism dependent on the cGAS/STING–TBK1–IRFs regulatory axis in mollusks, which was different from the classic cGAS–STING–TBK1 signal pathway in mammals.…”
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  4. 24
    DataSheet_1_The cGAS/STING–TBK1–IRF Regulatory Axis Orchestrates a Primitive Interferon-Like Antiviral Mechanism in Oyster.doc

    DataSheet_1_The cGAS/STING–TBK1–IRF Regulatory Axis Orchestrates a Primitive Interferon-Like Antiviral Mechanism in Oyster.doc by Xue Qiao (1409857)

    Published 2021
    “…These results indicated that there was a primitive IFN-like antiviral mechanism dependent on the cGAS/STING–TBK1–IRFs regulatory axis in mollusks, which was different from the classic cGAS–STING–TBK1 signal pathway in mammals.…”
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  5. 25
    Table_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.xlsx

    Table_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.xlsx by Sarah E. Elzinga (9235635)

    Published 2022
    “…Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. Collectively these studies suggest a role for early activation of the innate immune system both peripherally and centrally with potential inflammatory crosstalk between neurons and glia.…”
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  6. 26
    Image_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. Collectively these studies suggest a role for early activation of the innate immune system both peripherally and centrally with potential inflammatory crosstalk between neurons and glia.…”
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  7. 27
    Image_10_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_10_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. Collectively these studies suggest a role for early activation of the innate immune system both peripherally and centrally with potential inflammatory crosstalk between neurons and glia.…”
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  8. 28
    Image_9_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_9_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. Collectively these studies suggest a role for early activation of the innate immune system both peripherally and centrally with potential inflammatory crosstalk between neurons and glia.…”
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  9. 29
    Image_3_cGAS/STING and innate brain inflammation following acute high-fat feeding.jpeg

    Image_3_cGAS/STING and innate brain inflammation following acute high-fat feeding.jpeg by Sarah E. Elzinga (9235635)

    Published 2022
    “…Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. Collectively these studies suggest a role for early activation of the innate immune system both peripherally and centrally with potential inflammatory crosstalk between neurons and glia.…”
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  10. 30
    Image_2_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_2_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. Collectively these studies suggest a role for early activation of the innate immune system both peripherally and centrally with potential inflammatory crosstalk between neurons and glia.…”
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  11. 31
    Image_8_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_8_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. Collectively these studies suggest a role for early activation of the innate immune system both peripherally and centrally with potential inflammatory crosstalk between neurons and glia.…”
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  12. 32
    Image_7_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_7_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. Collectively these studies suggest a role for early activation of the innate immune system both peripherally and centrally with potential inflammatory crosstalk between neurons and glia.…”
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  13. 33
    Image_4_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_4_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. Collectively these studies suggest a role for early activation of the innate immune system both peripherally and centrally with potential inflammatory crosstalk between neurons and glia.…”
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  14. 34
    Image_6_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_6_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. Collectively these studies suggest a role for early activation of the innate immune system both peripherally and centrally with potential inflammatory crosstalk between neurons and glia.…”
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  15. 35
    Image_5_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_5_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. Collectively these studies suggest a role for early activation of the innate immune system both peripherally and centrally with potential inflammatory crosstalk between neurons and glia.…”
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  16. 36
    Image_2_Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.tif

    Image_2_Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.tif by Joseph R. Podojil (12050717)

    Published 2022
    “…<p>Cancer treatment utilizing infusion therapies to enhance the patient’s own immune response against the tumor have shown significant functionality in a small subpopulation of patients. …”
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  17. 37
    Table_7_Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.pdf

    Table_7_Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.pdf by Joseph R. Podojil (12050717)

    Published 2022
    “…<p>Cancer treatment utilizing infusion therapies to enhance the patient’s own immune response against the tumor have shown significant functionality in a small subpopulation of patients. …”
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  18. 38
    Table_2_Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.pdf

    Table_2_Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.pdf by Joseph R. Podojil (12050717)

    Published 2022
    “…<p>Cancer treatment utilizing infusion therapies to enhance the patient’s own immune response against the tumor have shown significant functionality in a small subpopulation of patients. …”
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  19. 39
    Table_8_Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.pdf

    Table_8_Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.pdf by Joseph R. Podojil (12050717)

    Published 2022
    “…<p>Cancer treatment utilizing infusion therapies to enhance the patient’s own immune response against the tumor have shown significant functionality in a small subpopulation of patients. …”
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  20. 40
    Image_1_Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.tif

    Image_1_Biodegradable nanoparticles induce cGAS/STING-dependent reprogramming of myeloid cells to promote tumor immunotherapy.tif by Joseph R. Podojil (12050717)

    Published 2022
    “…<p>Cancer treatment utilizing infusion therapies to enhance the patient’s own immune response against the tumor have shown significant functionality in a small subpopulation of patients. …”
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