Sensing of schistosome-derived DNA by cGAS in macrophages mediates type I IFN response to <i>S</i>. <i>japonicum</i> infection. by Le Liang (2144725)

Distribution of Differentially Expressed Genes (DEGs) in affected biological pathways in βA3ΔG91 lenses relative to WT lenses. by Akosua K. Boateng (21672931)

List of DEGs in S. aureus PS/Bac/317/16/W strain spiked PCs vs TSB with log2fold-change ≥ 2 or ≤ -2, p<0.05. by Basit Yousuf (630368)

Empirical Characterization of False Discovery Rates of Differentially Expressed Genes and Transcriptomic Benchmark Concentrations in Zebrafish Embryos by Hyojin Lee (182880)

Subjects:

Data Sheet 2_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.pdf by Yonghu Chen (2040136)

“…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”

Data Sheet 1_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.zip by Yonghu Chen (2040136)

“…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”

DEGs and enrichment analysis in HepG2 cells expressing HBx. by Jianhua Zhong (11351726)

Data Sheet 3_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…Background<p>Cyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. …”

Data Sheet 1_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…Background<p>Cyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. …”

Data Sheet 2_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…Background<p>Cyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. …”

Heatmaps of the top 536 differentially expressed genes (DEG) by calcitriol in CaSki cells with fold changes ranging from 1.5 to −1.5. by Euclides Avila (41023)

Data Sheet 2_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Data Sheet 3_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Data Sheet 1_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Fig 1 - by Liang Cao (135383)

Data Sheet 2_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx by Xin Zhou (54275)

“…</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …”

Data Sheet 1_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx by Xin Zhou (54275)

“…</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …”

Fig 9 - by Liang Cao (135383)

List pf primers used for qRT-PCR analysis of randomly selected upregulated and downregulated DEGs for S. aureus CBS2016-05 and PS/BAC/317/16/W strains when grown in PCs vs TSB. by Basit Yousuf (630368)

List of DEGs from neuronal cell analysis. by Sara Cuvertino (18892069)

“…We also identify hundreds of differentially expressed genes (DEGs) in iPSCs, NPs and CNs in KS1. In contrast with the epigenomic changes, the number of DEGs decrease as differentiation progresses. …”