pDNA-PK levels are decreased in absence of cGAS. by Elona Gusho (4688170)

Proteins from volcano plot which had notable increases or decreases listed in order of greatest to least significance (adjusted p-values). by Eiman Y. Ibrahim (10731078)

“…<p>Proteins from volcano plot which had notable increases or decreases listed in order of greatest to least significance (adjusted p-values).…”

Total tau levels are significantly decreased in the healthy older brains compared to the younger brains. by Shreyasi Chatterjee (3531506)

Most significant muscle activation values. by María Benito-de-Pedro (22057468)

Subjects:

Significant repeated measurements sEMG outcomes. by María Benito-de-Pedro (22057468)

Subjects:

Significant single measurement sEMG outcomes. by María Benito-de-Pedro (22057468)

Subjects:

Heat map of <i>S</i>. <i>carpocapsae</i> statistically significant proteins. by Peter E. Lillis (12368582)

Heat map of <i>H</i>. <i>megidis</i> statistically significant proteins. by Peter E. Lillis (12368582)

DWV abundance variable over time and greatest in October. by Cayley Faurot-Daniels (9354170)

“…The first derivative of the fitted spline in panel A was calculated to identify the rate of change of DWV abundance throughout time and 95% confidence intervals (gray) were built around the first derivative to distinguish time periods when the change in virus abundance is significantly different from zero. DWV abundance significantly decreased (red) from 0 to 100 days of the study and significantly increased (blue) from 150 to 250 days of the study.…”

cGAS exacerbates <i>Schistosoma japonicum</i> infection in mice. by Le Liang (2144725)

cGAS is required for an ISD, but not an LPS, -induced type I IFN response. by Le Liang (2144725)

Number of significantly significant (P < 0.05) differentially abundant (SSDA) proteins showing increased or decreased activity (fold change +/- 1.5-fold) relative to time 0 followi... by Peter E. Lillis (12368582)

Plot showing the significant correlation between participant age and QOLI_TOTDIFF. by Roger D. Newman-Norlund (14053467)

Subjects:

Upregulation of autophagy decreases the age-related accumulation of hyperphosphorylated tau and ameliorates tau-induced locomotor defects in human Tau (0N3R) expressing transgenic... by Shreyasi Chatterjee (3531506)

The cGAS-STING axis is essential for <i>Schistosoma japonicum</i> infection-induced type I IFN response. by Le Liang (2144725)

Visualisation of significantly differentially expressed genes (DEGs). by Mohammed A. Alfattah (18271622)

Sensing of schistosome-derived DNA by cGAS in macrophages mediates type I IFN response to <i>S</i>. <i>japonicum</i> infection. by Le Liang (2144725)

Data Sheet 2_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.pdf by Yonghu Chen (2040136)

“…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”

Data Sheet 1_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.zip by Yonghu Chen (2040136)

“…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”

Data Sheet 3_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…Background<p>Cyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. …”