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Showing 21 - 40 results of 139 for search '(( significant decrease cgas ) OR ( significant nn decrease ))*', query time: 0.91s Refine Results
  1. 21
    A proposed working model of how the GmNN1/FT2a-GmNYFA-C-GmENOD40 module regulates nodulation in soybean.

    A proposed working model of how the GmNN1/FT2a-GmNYFA-C-GmENOD40 module regulates nodulation in soybean. by Xinxin Li (281237)

    Published 2022
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  2. 22
    Sensing of schistosome-derived DNA by cGAS in macrophages mediates type I IFN response to <i>S</i>. <i>japonicum</i> infection.

    Sensing of schistosome-derived DNA by cGAS in macrophages mediates type I IFN response to <i>S</i>. <i>japonicum</i> infection. by Le Liang (2144725)

    Published 2022
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  3. 23
    Data Sheet 2_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.pdf

    Data Sheet 2_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.pdf by Yonghu Chen (2040136)

    Published 2025
    “…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”
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  4. 24
    Data Sheet 1_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.zip

    Data Sheet 1_KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis.zip by Yonghu Chen (2040136)

    Published 2025
    “…</p>Results<p>KAE significantly alleviated lipopolysaccharide-induced pulmonary injury by reducing inflammatory cell infiltration, alleviating pulmonary edema, enhancing antioxidant capacity, and decreasing levels of inflammatory cytokines in mouse lung tissues. …”
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  5. 25
    Data Sheet 3_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf

    Data Sheet 3_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

    Published 2025
    “…Background<p>Cyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. …”
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  6. 26
    Data Sheet 1_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf

    Data Sheet 1_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

    Published 2025
    “…Background<p>Cyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. …”
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  7. 27
    Data Sheet 2_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf

    Data Sheet 2_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

    Published 2025
    “…Background<p>Cyclic GMP-AMP synthase (cGAS)-stimulator-of-interferon genes (STING) pathway is a cytosolic DNA sensor system. …”
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  8. 28
    Data Sheet 2_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology, molecular dynamics, and experimental validation.xlsx

    Data Sheet 2_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

    Published 2025
    “…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
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  9. 29
    Data Sheet 3_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology, molecular dynamics, and experimental validation.xlsx

    Data Sheet 3_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

    Published 2025
    “…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
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  10. 30
    Data Sheet 1_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology, molecular dynamics, and experimental validation.docx

    Data Sheet 1_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

    Published 2025
    “…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”
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  11. 31
    Data Sheet 2_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx

    Data Sheet 2_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx by Xin Zhou (54275)

    Published 2025
    “…</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …”
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  12. 32
    Data Sheet 1_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx

    Data Sheet 1_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx by Xin Zhou (54275)

    Published 2025
    “…</p>Results<p>The proteomic profiling of lung tissues from LPS-challenged mice identified significant dysregulation of proteins integral to the cGAS-STING cascade and pyroptotic processes. …”
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  13. 33
    Data_Sheet_1_Porphyromonas gingivalis induces an inflammatory response via the cGAS-STING signaling pathway in a periodontitis mouse model.PDF

    Data_Sheet_1_Porphyromonas gingivalis induces an inflammatory response via the cGAS-STING signaling pathway in a periodontitis mouse model.PDF by Rong Bi (8764434)

    Published 2023
    “…Furthermore, we report that a STING inhibitor (SN-011) significantly decreased inflammatory cytokine production and osteoclast formation in a periodontitis mouse model with P. gingivalis. …”
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  14. 34
    Table_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.xlsx

    Table_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.xlsx by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
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  15. 35
    Image_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_1_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
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  16. 36
    Image_10_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_10_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
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  17. 37
    Image_9_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_9_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
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  18. 38
    Image_3_cGAS/STING and innate brain inflammation following acute high-fat feeding.jpeg

    Image_3_cGAS/STING and innate brain inflammation following acute high-fat feeding.jpeg by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
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  19. 39
    Image_2_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_2_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
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  20. 40
    Image_8_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif

    Image_8_cGAS/STING and innate brain inflammation following acute high-fat feeding.tif by Sarah E. Elzinga (9235635)

    Published 2022
    “…Central inflammatory changes included microglial activation in a pro-inflammatory environment with cGAS/STING activation. Blocking gap junctions in neuron-microglial co-cultures significantly decreased cGAS/STING activation. …”
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