Showing 20,281 - 20,300 results of 21,342 for search '(( significant decrease decrease ) OR ( ((significance has) OR (significance a)) decrease ))', query time: 0.62s Refine Results
  1. 20281

    Table 1_Exploring the antiviral potential of shikimic acid against Chikungunya virus through network pharmacology, molecular docking, and in vitro experiments.docx by Jialiang Xin (6941207)

    Published 2025
    “…<p>Chikungunya virus (CHIKV) is an arbovirus that can lead to chronic arthritis and significantly diminish the quality of life of patients. …”
  2. 20282

    Image 1_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif by Houle Guo (21264647)

    Published 2025
    “…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”
  3. 20283

    Supplementary Material for: MicroRNA-4497 is Downregulated in Pediatric Allergic Diseases and Suppresses Th2 Inflammation in an Animal Model by figshare admin karger (2628495)

    Published 2025
    “…Furthermore, levels of IL-4, MDC and methacholine Penh were significantly decreased in a miR-4497 treated mouse model. …”
  4. 20284

    Data Sheet 1_Desulfovibrio vulgaris exacerbates sepsis by inducing inflammation and oxidative stress in multiple organs.pdf by Rong Wu (152554)

    Published 2025
    “…Phosphorylation of MAPK and NF-κB pathways in peritoneal macrophages was significantly enhanced. Additionally, D. vulgaris amplified oxidative stress across multiple organs, as indicated by increased ROS levels and decreased antioxidant enzyme activity.…”
  5. 20285

    Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx by Feilong Yang (1472296)

    Published 2025
    “…Western blotting demonstrated that HDGF knockdown suppressed AKT/mTOR signaling, as indicated by reduced p-AKT and p-mTOR levels, and decreased VEGFA expression.</p>Conclusion<p>Our findings establish HDGF as a key promoter of HSCC progression through dual regulation of EMT and AKT/mTOR/VEGF pathways, suggesting its potential as a therapeutic target. …”
  6. 20286

    Data Sheet 1_The pan-cancer landscape of aldo-keto reductase1B10 reveals that its expression is diminished in gastric cancer.docx by Anqi Wu (3413069)

    Published 2024
    “…In the stomach, along with the diminishing of AKR1B10 expression, CD68+ macrophage increased and CD19+ B cell decreased in gastric cancer.</p>Discussion<p>These data indicates that AKR1B10 may be an important factor in the development and progression and a potential therapeutic target for multiple cancers, but plays as a protector in the gastric tissues.…”
  7. 20287

    Image 3_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif by Houle Guo (21264647)

    Published 2025
    “…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”
  8. 20288

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  9. 20289

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  10. 20290

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  11. 20291

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  12. 20292

    Engineering and Functional Expression of the Type III Secretion System in <i>Xenorhabdus</i>: Enhancing Insecticidal Efficacy and Expanding T3SE Libraries by Xiyin Huang (11528200)

    Published 2025
    “…In <i>Helicoverpa armigera</i> models, the engineered strain induced severe intestinal damage by suppressing antimicrobial peptide expression and demonstrated improved colonization and biocontrol efficacy (LC<sub>50</sub> decreased by 3.7-fold). Crucially, the TT01 derived T3SS mediated delivery of XopAa novel effector exhibiting YopJ-family homology and characteristic T3SS effector featuresinto host cells. …”
  13. 20293

    ABR wave I and IV parameters in response to clicks. by Carolin Jüchter (17384611)

    Published 2025
    “…The P1-N1 amplitude at 90 dB SPL (<b>A</b>) was significantly reduced two days post-trauma compared to pre-trauma and stayed decreased three weeks post-trauma. …”
  14. 20294

    Table1_Mechanism of abscisic acid in promoting softening of postharvest ‘Docteur Jules Guyot’ pear (Pyrus communis L.).docx by Xiaofei Xu (109890)

    Published 2024
    “…The contents of water-soluble pectin (WSP) and ionic-soluble pectin (ISP) increased, and covalent binding pectin (CBP) decreased under ABA treatment. Among the detected volatile aromatic substances, the highest-level substance of the fruit was ester, and the ABA treatment significantly promoted the amount of ester substances. …”
  15. 20295

    Effects and Potential Risks of Chiral Penflufen on Pickled Cowpea: Combined Microbiome and Metabolomics by Chao Guo (163795)

    Published 2025
    “…<i>Rac</i>-penflufen treatment significantly decreased the relative abundance of <i>Lactiplantibacillus</i> while increasing <i>Weissella</i>, but the opposite effects were found in <i>R</i>- and <i>S</i>-penflufen treatments. …”
  16. 20296

    DataSheet1_Morphological, physiological, and biochemical responses of three different soybean (Glycine max L.) varieties under salinity stress conditions.docx by Desilal Kokebie (19561915)

    Published 2024
    “…The concentrations of chlorophyll a and b decreased with increasing salinity. In addition, salinity significantly increased leaf electrolyte leakage (EL), lipid peroxidation, proline accumulation, and phenol and flavonoid content. …”
  17. 20297

    Table2_Mechanism of abscisic acid in promoting softening of postharvest ‘Docteur Jules Guyot’ pear (Pyrus communis L.).xlsx by Xiaofei Xu (109890)

    Published 2024
    “…The contents of water-soluble pectin (WSP) and ionic-soluble pectin (ISP) increased, and covalent binding pectin (CBP) decreased under ABA treatment. Among the detected volatile aromatic substances, the highest-level substance of the fruit was ester, and the ABA treatment significantly promoted the amount of ester substances. …”
  18. 20298

    Source data.xlsx by Qian Cheng (20991434)

    Published 2025
    “…This limitation restricts electrode thickness, decreases power density, and shortens battery lifetime. …”
  19. 20299

    DataSheet1_HER2 expression in different cell lines at different inoculation sites assessed by [52Mn]Mn-DOTAGA(anhydride)-trastuzumab.docx by Toàn Minh Ngô (21195116)

    Published 2025
    “…Purpose<p>Positron emission tomography (PET) hybrid imaging targeting HER2 requires antibodies labelled with longer half-life isotopes. With a suitable radiation profile, <sup>52</sup>Mn coupled with DOTAGA as a bifunctional chelator is a potential candidate. …”
  20. 20300

    Data Sheet 1_Effects of stand structure and soil depth on soil properties in Cryptomeria japonica plantations.xlsx by Laicong Luo (12521938)

    Published 2025
    “…Moreover, soils in stands with good structure exhibited higher organic carbon and total nitrogen contents, particularly in the surface soil layer (0–10 cm), while the C:N, C:P, and N:P ratios gradually decreased with increasing soil depth. The study demonstrated that maintaining a good stand structure—characterized by low canopy closure, high understory vegetation cover, and moderate stand density—can significantly improve soil porosity, water-holding capacity, and nutrient cycling efficiency. …”