DataSheet1_Association between amoxicillin administration and outcomes in critically ill patients with acute kidney injury.PDF by Xinyao Luo (12084194)

“…</p>Materials and Methods<p>We conducted a retrospective cohort analysis utilizing data from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. …”

Supplementary file 1_Scorpion-Centipede extracts mitigate ovariectomy-induced osteoporosis in mice through facilitating Cx3cr1 expression.docx by Jinghuai Ni (21023477)

“…In vitro experiments were conducted to evaluate the effects of SC on osteogenic and adipogenic differentiation in BMMSCs, MC3T3-E1, and 3T3-L1 cells.</p>Results<p>The results showed that SC treatment significantly improved bone mineral density (BMD), trabecular separation (Tb.Sp), trabecular thickness (Tb.Th), trabecular number (Tb.N), bone volume fraction (BV/TV), and trabecular pattern factor (Tb.Pf) in OVX mice. …”

Image 3_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg by Zexin Zhang (7507979)

“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”

DataSheet1_Lipocalin-2 drives neuropsychiatric and cutaneous disease in MRL/lpr mice.docx by Sayra J. Garcia (19748644)

“…Systemic disease was evaluated through measuring anti-nuclear antibodies by ELISA.</p>Results<p>In this study, we found that LCN2 deficiency significantly attenuates neuropsychiatric and cutaneous disease in MRL/lpr lupus prone mice, likely by decreasing local infiltration of immune cells into the brain and skin and reducing astrocyte activation in the hippocampus. …”

Table 6_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx by Jiayue Zhang (7832669)

“…Bayesian Age-Period-Cohort (BAPC) modeling was used to predict the incidence rates of different sex and age groups in 2036.</p>Results<p>The global all-age disability-adjusted life year (DALY) rate of ischemic stroke decreased by 34.90% between 1990 and 2021, with the highest disease burden in China, especially in males. …”

Data Sheet 1_Pan-cancer analysis reveals TRA16 as a master regulator of human carcinogenesis.pdf by Yanyan Zhu (32035)

“…Importantly, patients with high TRA16 expression demonstrated elevated TMB and decreased stromal and immune features.</p>Discussion<p>These findings highlight TRA16 as a potential master regulator of oncogenic processes, contributing to tumor progression through coordinated regulation of cell cycle genes, intercellular signaling, and genomic instability. …”

Image 3_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg by Bing Gu (276393)

“…In this study, we examined the influence of CBS/H₂S on anxiety and depression-like behavior following the inescapable foot shock (IFS) procedure during early adolescence (postnatal days 28-35) or adulthood (postnatal days 63-70).</p>Results<p>Our results showed that adult PTSD mice exhibited more pronounced decreases in H₂S content and CBS expression in the hippocampus, which were associated with anxiety and depression-like behavior compared with adolescent PTSD mice. …”

Data Sheet 1_Early coronary angiography in patients with myocardial infarction without ST elevation after out-of-hospital cardiac arrest: a systematic review and meta-analysis.pdf by Warda Ahmed (5593586)

“…Background<p>Early coronary angiography (CAG) in post-cardiac arrest patients without ST-segment elevation is a topic of debate. …”

Data Sheet 1_Effect of cultivation feed diet using local food processing by-products on the growth and flavor factor in the Malabar grouper Epinephelus malabaricus.docx by Makoto Takahashi (386772)

“…Growth performance, liver somatic index, insulin-like growth factor 1 (IGF-1) gene expression, and muscle taste-related components were analyzed.</p>Results<p>FW-D-fed fish showed slightly lower growth performance, possibly due to decreased protein content. …”

Image 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.tif by Yan Cheng (149222)

“…Subsequently, a series of experiments such as qRT-PCR, Western blot, CCK-8, flow cytometry and ELISA were used to verify the potential mechanism of MFN2.</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”

Table 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx by Yihan Liu (2258221)

“…Macrophage polarization and migratory capacity were assessed following manipulation of OIP5-AS1, miR-429, and DOCK4 expression.</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …”

Image 1_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg by Bing Gu (276393)

“…In this study, we examined the influence of CBS/H₂S on anxiety and depression-like behavior following the inescapable foot shock (IFS) procedure during early adolescence (postnatal days 28-35) or adulthood (postnatal days 63-70).</p>Results<p>Our results showed that adult PTSD mice exhibited more pronounced decreases in H₂S content and CBS expression in the hippocampus, which were associated with anxiety and depression-like behavior compared with adolescent PTSD mice. …”

Data Sheet 1_LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis.docx by Yihan Liu (2258221)

“…Macrophage polarization and migratory capacity were assessed following manipulation of OIP5-AS1, miR-429, and DOCK4 expression.</p>Results<p>OIP5-AS1 expression was significantly decreased in LUAD tissues and associated with poor survival. …”

Data Sheet 2_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.xlsx by Bing Gu (276393)

“…In this study, we examined the influence of CBS/H₂S on anxiety and depression-like behavior following the inescapable foot shock (IFS) procedure during early adolescence (postnatal days 28-35) or adulthood (postnatal days 63-70).</p>Results<p>Our results showed that adult PTSD mice exhibited more pronounced decreases in H₂S content and CBS expression in the hippocampus, which were associated with anxiety and depression-like behavior compared with adolescent PTSD mice. …”

Table 2_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a... by Linxi Qian (555385)

“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”

Comparison of 3D culture systems on mesenchymal stem cell longevity, regenerative potential, and secretome production by Jacob Hodge (2699521)

“…Cultures were assessed for proliferation, senescence, apoptosis, trilineage differentiation, stem-like gene expression, secretome protein and extracellular vesicle (EV) production, and EV potency on endothelial cells (ECs).</p> <p>Bio-Block ASCs exhibited ~2-fold higher proliferation than spheroid and Matrigel groups, with senescence reduced 30–37% and apoptosis decreased 2–3-fold. …”

Supplementary Material for: Reduction of waste mass in used hemodialysis circuits by QCC activity by figshare admin karger (2628495)

“…Results: Implementation of QCC interventions resulted in a 29.7% reduction in mean circuit mass, decreasing from 0.64±0.015 kg to 0.45±0.012 kg (p<0.01) across the sampled hemodialysis apparatus. …”

Table 1_From feed to field: effect of dietary protein level and use of a blend of feed additives on gaseous emissions from growing-finishing pig slurry.docx by Esperanza Fuertes (20628794)

“…The low-protein diet supplemented with additives (LPA) significantly reduced slurry pH (P ≤ 0.001) and urinary NH₃-N excretion (interaction, P = 0.03), improving nutrient digestibility and lowering organic matter content in slurry (P < 0.05). …”

Effect of COVID-19 infection on thyroid function status and clinical indexes among hypothyroid outpatients by Bingxin Li (1876975)

“…In HT group, thyroid-stimulating hormone (TSH) levels decreased significantly compared to pre-infection levels (<i>p</i> = 0.013), while free triiodothyronine (FT3) levels increased at D90 compared to both D30 post-infection and pre-infection levels (<i>p</i> < 0.001 and <i>p</i> = 0.005). …”

Table 1_Optimization of Artemisia ordosica crude polysaccharides on milk fatty acid composition in lactating donkeys and their effects on rectal microbiome and lactation performanc... by Fanzhu Meng (20418071)

“…The trial lasted 10 weeks (including a 2-week adaptation period).</p>Results and discussion<p>Compared with the CON group, AOCP supplementation significantly enhanced lactation performance (milk yield, fat, lactose) and the digestibility of DM, ADF, NDF, and elevated oleic acid, linoleic acid, eicosapentaenoic acid, as well as the unsaturated-to-saturated (U/S) and polyunsaturated-to-saturated (P/S) fatty acid ratios, while reducing saturated fatty acids and the c index. …”