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significance step » significance set (Expand Search), significance test (Expand Search), significance level (Expand Search)
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20421
Table 1_The association between dietary creatine intake and cancer in U.S. adults: insights from NHANES 2007–2018.docx
Published 2025“…For each standard deviation (SD) increase in dietary creatine intake, cancer risk decreased by 5% (adjusted odds ratio (OR) = 0.95, 95% CI: 0.91–0.99, p = 0.025). …”
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20422
Table 1_The role of serum albumin and albumin-related nutritional indices in predicting post-stroke cognitive impairment: a systematic review and meta-analysis.docx
Published 2025“…</p>Conclusion<p>Decreased serum albumin levels and albumin-related nutritional indices (GNRI and HALP scores) have a strong correlation with PSCI, which may become important indicators for early prediction of the development of PSCI.…”
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20423
The T-type voltage-gated Ca<sup>2+</sup> channel Ca<sub>V</sub>3.1 involves in the disruption of respiratory epithelial barrier induced by <i>Pasteurella multocida</i> toxin
Published 2025“…<p><i>Pasteurella multocida</i> toxin (PMT) is an exotoxin produced by several members of the zoonotic respiratory pathogen <i>P. multocida</i>. …”
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20424
Table 1_Disc degeneration influences the strain magnitude and stress distribution within the adjacent trabecular bone.docx
Published 2024“…Von Mises stress distribution was significantly skewed towards the anterior region in the degenerated group only (28.3% ± 10.4%, p < 0.05). …”
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20425
Table 1_Baicalein from Scutellaria baicalensis mitigates oxidative stress through the IIS pathway in a C. elegans model of ulcerative colitis.docx
Published 2025“…The effects of 25 μM, 50 μM, and 100 μM of baicalein on intestinal barrier function, oxidative stress markers, and relevant gene expression were evaluated, including genes related to epithelial barrier integrity (clc-2, mtm-6, etc.), oxidative stress, and the IIS and p38 MAPK pathways.</p>Results<p>Baicalein significantly improved physiological condition and intestinal permeability in worm treated with 5% DSS. …”
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20426
DataSheet1_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.docx
Published 2024“…Immunohistochemical analysis showed tofacitinib significantly decreased the pSTAT3 and pSTAT6 levels in the skin lesions of this patient. …”
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20427
Data Sheet 1_Personalized temporal interference stimulation targeting striatum reduces functional stability and dynamic connectivity variability in the sensorimotor network.docx
Published 2025“…Seed-based dFC variability in the right striatum was measured as the standard deviation of dFC across windows.</p>Results<p>(1) Functional stability: TI stimulation significantly decreased functional stability in bilateral SMA regions (predominantly SMA proper, with parts of pre-SMA) compared to Sham and baseline conditions (P < 0.01). (2) Dynamic functional connectivity: TI stimulation reduced dFC variability between the right striatum and left SMA region (predominantly SMA proper, with parts of pre-SMA) compared to baseline (P < 0.01). (3) Safety: No adverse cognitive effects or side effects were observed, with good blinding effectiveness maintained throughout the study.…”
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20428
DataSheet2_Treatment and molecular analysis of bullous pemphigoid with tofacitinib: a case report and review of current literature.xlsx
Published 2024“…Immunohistochemical analysis showed tofacitinib significantly decreased the pSTAT3 and pSTAT6 levels in the skin lesions of this patient. …”
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20429
Table1_Protective effect of Huanglian Pingwei San on DSS-induced ulcerative colitis in mice through amelioration of the inflammatory response and oxidative stress.DOC
Published 2024“…HLPWS dose-dependently decreased the number of apoptotic cells by inhibiting P53, P21, P27, cleaved caspase 3, and p-H2AX expression. …”
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20430
Database of the impact of temperature on development of Aedes aegypti and Aedes albopictus in Cambodia
Published 2025“…Bionomic parameters were measured from hatching rate of F2 eggs until number of F3 eggs, in triplicate for each temperature treatment.</p><p dir="ltr"><b>Results</b>: Temperature significantly influenced all life-history traits of <i>Ae. aegypti</i> and <i>Ae. albopictus</i>. …”
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20431
Table 1_Global and regional burdens of opioid use disorder from 1990 to 2021, with future forecasts to 2050: a systematic analysis for the global burden of disease study 2021.docx
Published 2025“…Population growth and epidemiological changes contributed significantly to the increase in the burden of OUD.</p>…”
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20432
Image 1_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif
Published 2025“…Cytokine expression, relative abundance of the main bacterial phyla and genera, and levels of short-chain fatty acids were analyzed in the intestinal milieu.</p>Results<p>Treatment with AFs at 0.1 g/kg significantly reduced ear thickness at 1- and 6-hours post-DNCB application. …”
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20433
Data Sheet 1_Epigallocatechin-3-gallate protects against osteoarthritis-induced chondrocytes dysfunction by regulating PLa2g2a.pdf
Published 2025“…Subsequently, an OA model in rats was induced by intra-articular injection of monoiodoacetic acid (MIA), and EGCG was administered for OA treatment to validate the expression of the differentially expressed genes.</p>Results<p>EGCG could reduce reactive oxygen species (ROS) levels and decreased the expression of inflammatory cytokines IL-β, MMP13, and TNF-α. …”
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20434
Data Sheet 1_Comprehensive analysis of metabolism-related genes in sepsis reveals metabolic–immune heterogeneity and highlights GYG1 as a potential therapeutic target.csv
Published 2025“…In vivo, Gyg1 was markedly upregulated in septic mice, and LNP-mediated siRNA knockdown of Gyg1 significantly improved survival in the LPS model. Mechanistically, Gyg1 knockdown significantly reduced glycogen content in myeloid cells, attenuated IL-6 and TNF-α production, alleviated LPS-induced neutrophil, and modestly decreased CD40 expression in monocytes and dendritic cells. …”
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20435
DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx
Published 2024“…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …”
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20436
Data Sheet 1_Global, regional and national mortality burden of laryngeal cancer attributable to occupational exposure to sulfuric acid and asbestos: 1990–2021 and projections to 20...
Published 2025“…Background<p>Laryngeal cancer (LC) is the most prevalent form of head and neck cancer, significantly impacting patients' health. …”
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20437
Data Sheet 1_Negative effects of adverse childhood experiences and absence of positive childhood experiences on healthcare employees: survey findings built on 10 years of trauma-in...
Published 2025“…Having 0–2 PCEs relative to 6–7 PCEs was also significantly associated with greater odds of past 2-week compassion fatigue, a lower resilience score, and decreased odds of reported organizational belonging measures. …”
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20438
Data Sheet 3_Global, regional and national mortality burden of laryngeal cancer attributable to occupational exposure to sulfuric acid and asbestos: 1990–2021 and projections to 20...
Published 2025“…Background<p>Laryngeal cancer (LC) is the most prevalent form of head and neck cancer, significantly impacting patients' health. …”
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20439
Image 2_Immunomodulatory and anti-inflammatory effects of agave fructans in atopic dermatitis: gut microbiota and short-chain fatty acid implication.tif
Published 2025“…Cytokine expression, relative abundance of the main bacterial phyla and genera, and levels of short-chain fatty acids were analyzed in the intestinal milieu.</p>Results<p>Treatment with AFs at 0.1 g/kg significantly reduced ear thickness at 1- and 6-hours post-DNCB application. …”
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20440
Data Sheet 2_Global, regional and national mortality burden of laryngeal cancer attributable to occupational exposure to sulfuric acid and asbestos: 1990–2021 and projections to 20...
Published 2025“…Background<p>Laryngeal cancer (LC) is the most prevalent form of head and neck cancer, significantly impacting patients' health. …”