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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant 17 » significant _ (Expand Search), significant co (Expand Search), significant anti (Expand Search)
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20881
Table1_SMAD4 enhances the cytotoxic efficacy of human NK cells against colorectal cancer cells via the m6A reader YTHDF2.docx
Published 2024“…</p>Results<p>Our findings revealed that the expression of SMAD4 is decreased in NK cells within the TME of human CRC. …”
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20882
Image 3_Natural killer cell as a potential predictive biomarker for early immune checkpoint inhibitor-associated cardiovascular adverse events: a retrospective cohort study.tif
Published 2025“…</p>Results<p>ScRNA-seq data revealed decreased CD8+ T and B cell proportions in the CVAEs group, while NK cell proportions increased. …”
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20883
Image 2_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with foreca...
Published 2025“…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …”
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20884
Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i> in an organotypic 3D lung epithelial cell model
Published 2025“…Compared to the <i>lasB</i> mutant, the wild-type strain significantly decreased inflammation by degrading MCP-1, IL-1β, GM-CSF, and IL-8. …”
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20885
Image 1_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.tiff
Published 2025“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
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20886
Data Sheet 1_Quantitative MRCP metrics as imaging biomarkers to differentiate benign from malignant bile duct obstructions.docx
Published 2025“…If detected early, surgical resection carries a 35% 5-year survival rate; this decreases to <11% 1-year survival rate when detected at later stages. …”
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20887
DataSheet1_Integration of smart charging of large-scale electric vehicles into generation and storage expansion planning: a case study in south china.pdf
Published 2024“…The numerical results show that the implementation of smart charging can significantly alter the decisions of GSEP. As the participation rate of smart charging improves from 0% to 90%, there is an additional 1,800 MW installation in wind and solar power, while the need to build new batteries is noticeably reduced; also, depending on the level of EV uptake, the annualized total system cost decreases by 5.11%–7.57%, and the curtailment of wind and solar power is reduced by 10.34%–19.64%. …”
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20888
Data Sheet 1_An active ingredient from the combination of Corydalis Rhizoma and Paeoniae Radix Alba relieves chronic compression injury-induced pain in rats by ameliorating AR/Mboa...
Published 2025“…</p>Results<p>The results demonstrated that YB60 significantly decreased inflammatory cytokine levels both in cellular models and rat serum, while concurrently elevating pain thresholds in CCI rats. …”
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20889
Image 1_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif
Published 2025“…We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …”
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20890
Data Sheet 1_Effects of aging and valence on emotional response inhibition: conclusions from a novel stop-signal task.pdf
Published 2025“…Aging is associated with decreasing cognitive control and inhibition alongside improvements in emotional control and regulation. …”
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20891
Table 1_The role of cyano-phycocyanin as a quorum sensing inhibitor to attenuate Pseudomonas aeruginosa virulence.docx
Published 2025“…In vitro, C-PC reduced the adhesion and invasion of PA2 in RAW264.7 cells, and decreased LDH release and macrophage damage caused by PA2 infection. …”
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20892
The prognostic value of the neutrophil-percentage-to-albumin ratio for all-cause and cardiovascular mortality in chronic kidney disease stages G3a to G5: insights from NHANES 2003–...
Published 2025“…High levels NPAR exhibited a significantly elevated risk of both all-cause and CVD mortality in the fully adjusted model. …”
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20893
Data Sheet 1_Renewable energy consumption optimization allocation strategy for a regional microgrid based on a shared energy storage mechanism.zip
Published 2025“…This indicates that the proposed method for constructing a bilayer optimization configuration can effectively consider the economic consumption of new energy and significantly improve the economic operation of shared energy storage stations and regional microgrids.…”
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20894
Data Sheet 1_IgE autoantibodies to nuclear antigens in patients with different connective tissue diseases: re-evaluation and novel findings.docx
Published 2025“…</p>Results<p>In SLE and SS, IgE anti-SSA/Ro52-, -SSA/Ro60- and -SSB/La-antibodies showed a significantly higher reactivity than in controls. IgE anti-dsDNA-antibodies were present in 66% of SLE patients. …”
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20895
Table 11_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
Published 2025“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”
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20896
Table 1_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.docx
Published 2025“…Notably, its prognostic significance appears to be tumor-type specific, associating with either favorable or poor outcomes depending on the cancer context.…”
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20897
Image 3_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg
Published 2025“…Notably, its prognostic significance appears to be tumor-type specific, associating with either favorable or poor outcomes depending on the cancer context.…”
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20898
Image 6_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg
Published 2024“…However, pretreatment with SBP followed by H<sub>2</sub>O<sub>2</sub> inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H<sub>2</sub>O<sub>2</sub>–induced cells. …”
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20899
Table 1_Xinfeng Capsule inhibits oxidative stress via regulating the PPARγ/ Hmgcs2 signaling pathway in lung tissue of adjuvant arthritis rats.docx
Published 2025“…Furthermore, XFC-containing serum suppressed TGF-β1–induced proliferation of lung fibroblasts, promoted PPARγ expression, and significantly decreased the levels of interleukin-6, tumor necrosis factor-α, reactive oxygen species, nicotinamide adenine dinucleotide phosphate oxidase 4, HMGCS2, collagen type I α 1, collagen type III α 1, and α-smooth muscle actin (P < 0.01). …”
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20900
Table 1_Association between Life’s Crucial 9 and metabolic dysfunction-associated steatotic liver disease: the mediating role of neutrophil-percentage-to-albumin ratio.docx
Published 2025“…After adjusting for all confounders, LC9 was significantly and negatively associated with both MASLD (OR = 0.59, 95% CI: 0.54–0.64) and hepatic fibrosis (OR = 0.66, 95% CI: 0.45–0.97), with each 10-point increase in the LC9 score decreasing the prevalence by 41% and 34%, respectively. …”