يعرض 21,081 - 21,100 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( ((significant 17) OR (significant gap)) decrease ))', وقت الاستعلام: 0.59s تنقيح النتائج
  1. 21081

    Effects of extracts on organs weight. حسب Srabonti Saha (17452756)

    منشور في 2025
    "…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …"
  2. 21082

    Data Sheet 1_Comprehensive metagenomic and lipidomic analysis showed that baicalin could improve depressive behaviour in atherosclerotic mice by inhibiting nerve cell ferroptosis.z... حسب Peng Ren (337555)

    منشور في 2025
    "…Metabolic pathway enrichment analysis showed that differential lipid PEs were significantly enriched in the iron death pathway, and our further in vitro cellular experiments showed that baicalin could inhibit Erastin-induced Ferroptosis in the hippocampal neuronal cell line HT-22 by promoting the expression of SLC7A11, GSH, and GPX4, inhibiting the expression of ACSL4, and decreasing the cellular ROS.…"
  3. 21083

    Table 2_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx حسب Shuman Li (652613)

    منشور في 2025
    "…</p>Results<p>In comparison to controls, NEAT1 expression was significantly elevated in the epithelial tissues of CRSwNP. …"
  4. 21084

    Flexible Microfluidic Devices for Tunable Formation of Double Emulsion حسب Uditha Roshan (20841937)

    منشور في 2025
    "…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…"
  5. 21085

    Image 4_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif حسب Rong Su (2210740)

    منشور في 2025
    "…In vitro, the overexpression of miR-4739 in Huh-7 cells significantly induced SPP1<sup>+</sup> macrophages, and the culture medium derived from SPP1<sup>+</sup> macrophages further promoted the proliferation and migration of Huh-7 cells. …"
  6. 21086

    Data Sheet 1_Exhaustion of NK cells and interferon activation in anti-MDA5+ dermatomyositis are associated and determine the development of ILD.docx حسب Chenyi Shao (6444911)

    منشور في 2025
    "…Flow cytometry confirmed significantly decreased NK cell counts and increased apoptosis in the ILD group. …"
  7. 21087

    Flexible Microfluidic Devices for Tunable Formation of Double Emulsion حسب Uditha Roshan (20841937)

    منشور في 2025
    "…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…"
  8. 21088

    Interim Effects of Zoledronate, Denosumab, or Teriparatide on Bone Microarchitecture in Type 2 Diabetes: A Pilot Trial حسب Trupti Nagendra Prasad (17266455)

    منشور في 2025
    "…Micro finite element analysis-derived strength parameters were unchanged, except for modest increase in tibial stiffness with denosumab. BTMs decreased with anti-resorptives, increased with teriparatide and showed an anabolic window by 6 weeks.…"
  9. 21089

    Table 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx حسب Rong Su (2210740)

    منشور في 2025
    "…In vitro, the overexpression of miR-4739 in Huh-7 cells significantly induced SPP1<sup>+</sup> macrophages, and the culture medium derived from SPP1<sup>+</sup> macrophages further promoted the proliferation and migration of Huh-7 cells. …"
  10. 21090

    Figure 6 from Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell Composition but Differ in Immune Cell Phenotypes حسب Laura Kuett (20493991)

    منشور في 2025
    "…<b>F</b> and <b>G,</b> Immune cell phenotypic cluster enrichment in each clinical breast cancer subtype (<b>F</b>) or metastasis-defined patient group (<b>G</b>) at metastatic sites compared with average metastasis composition by differential abundance testing. Circles display significantly enriched (red) or decreased (blue; FDR < 0.05; multiple testing correction with the Benjamin–Hochberg method) results, with size indicating the log-transformed fold change.  …"
  11. 21091

    Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip حسب Erli Wu (17785482)

    منشور في 2025
    "…</p>Results<p>scRNA-seq analysis revealed a decreased proportion of HGFs alongside enrichment of multiple PANoptosis-related pathways in PD samples. …"
  12. 21092

    DataSheet2_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf حسب Jianan Zhang (786459)

    منشور في 2025
    "…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …"
  13. 21093

    DNA damage protecting effects of PEExCC. حسب Srabonti Saha (17452756)

    منشور في 2025
    "…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …"
  14. 21094

    Supplementary file 1_Oral bacterial community dynamics during induction of gingival inflammation.docx حسب Bart J. F. Keijser (16884185)

    منشور في 2025
    "…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …"
  15. 21095

    Table 3_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx حسب Jingjing Chen (293564)

    منشور في 2025
    "…</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …"
  16. 21096

    Image 5_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif حسب Meirong Feng (22089665)

    منشور في 2025
    "…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …"
  17. 21097

    Flexible Microfluidic Devices for Tunable Formation of Double Emulsion حسب Uditha Roshan (20841937)

    منشور في 2025
    "…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…"
  18. 21098

    Table 1_Moderating effects of a healthy lifestyle on the association of pre-metabolic syndrome with multiple chronic disease comorbidities.docx حسب Youqiong Xu (18161893)

    منشور في 2025
    "…PreMetS [OR = 1.38, 95%CI: 1.16–1.64] and MetS [OR = 1.61, 95%CI: 1.32–1.97] were associated with a significantly higher risk of multiple comorbidities compared with the normal population, and the risk of multiple comorbidities tended to increase as the number of metabolic disorder components increased (p < 0.001). …"
  19. 21099

    Glucagon-like peptide-1 receptor agonists, inflammation, and kidney diseases: evidence from Mendelian randomization حسب Yu-Xuan Yao (21338594)

    منشور في 2025
    "…</p> <p>After meta-analyses of both discovery and validation cohorts, genetically proxied GLP1R agonist was found to significantly associated with a decreased risk of diabetic nephropathy (OR = 0.72, 95%CI = 0.54–0.97, <i>p</i> = 0.031) and IgA nephropathy (OR = 0.58, 95%CI = 0.36–0.94, <i>p</i> = 0.027). …"
  20. 21100

    Data Sheet 1_Listening to mom in the neonatal intensive care unit: a randomized trial of increased maternal speech exposure on white matter connectivity in infants born preterm.pdf حسب Katherine E. Travis (6680396)

    منشور في 2025
    "…We hypothesized that neonates randomized to the T-group would show evidence for increased maturation within the arcuate, indexed as decreased MD and increased FA and R1, compared to neonates in the C-group.…"