بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significant 17 » significant _ (توسيع البحث), significant co (توسيع البحث), significant anti (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significant 17 » significant _ (توسيع البحث), significant co (توسيع البحث), significant anti (توسيع البحث)
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21081
Effects of extracts on organs weight.
منشور في 2025"…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …"
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21082
Data Sheet 1_Comprehensive metagenomic and lipidomic analysis showed that baicalin could improve depressive behaviour in atherosclerotic mice by inhibiting nerve cell ferroptosis.z...
منشور في 2025"…Metabolic pathway enrichment analysis showed that differential lipid PEs were significantly enriched in the iron death pathway, and our further in vitro cellular experiments showed that baicalin could inhibit Erastin-induced Ferroptosis in the hippocampal neuronal cell line HT-22 by promoting the expression of SLC7A11, GSH, and GPX4, inhibiting the expression of ACSL4, and decreasing the cellular ROS.…"
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21083
Table 2_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx
منشور في 2025"…</p>Results<p>In comparison to controls, NEAT1 expression was significantly elevated in the epithelial tissues of CRSwNP. …"
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21084
Flexible Microfluidic Devices for Tunable Formation of Double Emulsion
منشور في 2025"…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…"
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21085
Image 4_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif
منشور في 2025"…In vitro, the overexpression of miR-4739 in Huh-7 cells significantly induced SPP1<sup>+</sup> macrophages, and the culture medium derived from SPP1<sup>+</sup> macrophages further promoted the proliferation and migration of Huh-7 cells. …"
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21086
Data Sheet 1_Exhaustion of NK cells and interferon activation in anti-MDA5+ dermatomyositis are associated and determine the development of ILD.docx
منشور في 2025"…Flow cytometry confirmed significantly decreased NK cell counts and increased apoptosis in the ILD group. …"
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21087
Flexible Microfluidic Devices for Tunable Formation of Double Emulsion
منشور في 2025"…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…"
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21088
Interim Effects of Zoledronate, Denosumab, or Teriparatide on Bone Microarchitecture in Type 2 Diabetes: A Pilot Trial
منشور في 2025"…Micro finite element analysis-derived strength parameters were unchanged, except for modest increase in tibial stiffness with denosumab. BTMs decreased with anti-resorptives, increased with teriparatide and showed an anabolic window by 6 weeks.…"
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21089
Table 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx
منشور في 2025"…In vitro, the overexpression of miR-4739 in Huh-7 cells significantly induced SPP1<sup>+</sup> macrophages, and the culture medium derived from SPP1<sup>+</sup> macrophages further promoted the proliferation and migration of Huh-7 cells. …"
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21090
Figure 6 from Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell Composition but Differ in Immune Cell Phenotypes
منشور في 2025"…<b>F</b> and <b>G,</b> Immune cell phenotypic cluster enrichment in each clinical breast cancer subtype (<b>F</b>) or metastasis-defined patient group (<b>G</b>) at metastatic sites compared with average metastasis composition by differential abundance testing. Circles display significantly enriched (red) or decreased (blue; FDR < 0.05; multiple testing correction with the Benjamin–Hochberg method) results, with size indicating the log-transformed fold change. …"
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21091
Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip
منشور في 2025"…</p>Results<p>scRNA-seq analysis revealed a decreased proportion of HGFs alongside enrichment of multiple PANoptosis-related pathways in PD samples. …"
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21092
DataSheet2_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf
منشور في 2025"…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …"
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21093
DNA damage protecting effects of PEExCC.
منشور في 2025"…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …"
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21094
Supplementary file 1_Oral bacterial community dynamics during induction of gingival inflammation.docx
منشور في 2025"…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …"
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21095
Table 3_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx
منشور في 2025"…</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …"
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21096
Image 5_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif
منشور في 2025"…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …"
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21097
Flexible Microfluidic Devices for Tunable Formation of Double Emulsion
منشور في 2025"…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…"
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21098
Table 1_Moderating effects of a healthy lifestyle on the association of pre-metabolic syndrome with multiple chronic disease comorbidities.docx
منشور في 2025"…PreMetS [OR = 1.38, 95%CI: 1.16–1.64] and MetS [OR = 1.61, 95%CI: 1.32–1.97] were associated with a significantly higher risk of multiple comorbidities compared with the normal population, and the risk of multiple comorbidities tended to increase as the number of metabolic disorder components increased (p < 0.001). …"
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21099
Glucagon-like peptide-1 receptor agonists, inflammation, and kidney diseases: evidence from Mendelian randomization
منشور في 2025"…</p> <p>After meta-analyses of both discovery and validation cohorts, genetically proxied GLP1R agonist was found to significantly associated with a decreased risk of diabetic nephropathy (OR = 0.72, 95%CI = 0.54–0.97, <i>p</i> = 0.031) and IgA nephropathy (OR = 0.58, 95%CI = 0.36–0.94, <i>p</i> = 0.027). …"
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21100
Data Sheet 1_Listening to mom in the neonatal intensive care unit: a randomized trial of increased maternal speech exposure on white matter connectivity in infants born preterm.pdf
منشور في 2025"…We hypothesized that neonates randomized to the T-group would show evidence for increased maturation within the arcuate, indexed as decreased MD and increased FA and R1, compared to neonates in the C-group.…"