Raw data for quantitative real-time PCR analysis. by Hyerim Park (303433)

“…Furthermore, Lp^WJL supplementation induced the expression of the key growth factor IGF-1 while decreasing muscle atrophy markers such as Atrogin-1 and MuRF-1, indicating potential mechanisms by which protein malnutrition-induced muscle wasting is counteracted. …”

Raw data for body and muscle weights. by Hyerim Park (303433)

“…Furthermore, Lp^WJL supplementation induced the expression of the key growth factor IGF-1 while decreasing muscle atrophy markers such as Atrogin-1 and MuRF-1, indicating potential mechanisms by which protein malnutrition-induced muscle wasting is counteracted. …”

Raw data for micro-CT analysis of the femur. by Hyerim Park (303433)

“…Furthermore, Lp^WJL supplementation induced the expression of the key growth factor IGF-1 while decreasing muscle atrophy markers such as Atrogin-1 and MuRF-1, indicating potential mechanisms by which protein malnutrition-induced muscle wasting is counteracted. …”

Real-time PCR primer sequences. by Hyerim Park (303433)

“…Furthermore, Lp^WJL supplementation induced the expression of the key growth factor IGF-1 while decreasing muscle atrophy markers such as Atrogin-1 and MuRF-1, indicating potential mechanisms by which protein malnutrition-induced muscle wasting is counteracted. …”

Dupilumab improves sense of smell and clinical outcomes in patients with severe chronic rhinosinusitis with nasal polyps with anosmia by Andrew P. Lane (20367704)

“…At week 24, the proportion of dupilumab-treated patients with anosmia decreased to 28.5%, while 14.9% achieved normosmia; most placebo-group patients (79.2%) remained anosmic and only 1.2% achieved normosmia (odds ratio = 17.3; 95% confidence interval = 5.1–59.0; <i>p</i> <.0001); results were similar at week 52. …”

Image 2_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…</p>Results<p>Upon infection of these cells with MNoV_S99, we unexpectedly observed that only cells expressing the YFP-Ubiquitin_K48R protein showed a significantly impaired expression of several viral markers: NS5, NS7, VP1 and the replication intermediate dsRNA. …”

Table3_Maslinic acid induces autophagy and ferroptosis via transcriptomic and metabolomic reprogramming in prostate cancer cells.xlsx by Fen Hu (342627)

“…Further, MA was observed to induce prostate cancer cell autophagy by increasing the expression of p53, p-p53, ULK1, Beclin1, Atg7, and Atg5 and the ratio of LC3-II/I and concurrently decreasing the expression of ERK1/2 and mTOR. …”

Table2_Maslinic acid induces autophagy and ferroptosis via transcriptomic and metabolomic reprogramming in prostate cancer cells.xlsx by Fen Hu (342627)

“…Further, MA was observed to induce prostate cancer cell autophagy by increasing the expression of p53, p-p53, ULK1, Beclin1, Atg7, and Atg5 and the ratio of LC3-II/I and concurrently decreasing the expression of ERK1/2 and mTOR. …”

<b>Mystery of Deep Soil Organic Carbon Dynamics Uncovered through Long-term Conservation Tillage Experiments</b> by Jianye Li (8914520)

“…</a> Yet, the composition and origins of SOC in boreal regions—particular in deep soil profiles (i.e., 20–100 cm) —remain unclear. …”

Long-term changes in macronutrients, micronutrients, and potentially toxic elements under 33 years of continuous chemical fertilizer and organic matter application by Toan Nguyen-Sy (6333815)

“…The content of macronutrient elements (Ca, Mg, P, and K) remained stable with organic matter added treatments, with Ca and P significantly correlating with C and N (<i>p</i> < 0.05). …”

Data Sheet 2_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.docx by Arjanneke F. van de Merbel (5809940)

“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”

Supplementary file 2_Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fi... by Shuting Li (6552)

“…By intersecting 148 drug targets with the 249 disease targets, four therapeutic targets for SAL treatment against peritoneal fibrosis were pinpointed: cathepsin S, VDR, plasminogen activator urokinase, and galectin 3. In a murine model of peritoneal fibrosis induced by intraperitoneal injection of 4.25% PD fluid, SAL treatment significantly mitigated peritoneal fibrosis, as evidenced by reduced collagen deposition, decreased protein expression of α-smooth muscle actin and Collagen I, and a thinner peritoneum. …”

Table 2_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…In MAFLD mice, TFA treatment significantly decreased body weight gain, hepatic lipid accumulation, and the serum levels of ALT, AST, TC, and TG. …”

<b>Concurrent initiation of treadmill exercise protects against angiotensin II-induced renal injury by modulating oxidative stress and autophagy in mice</b> by Ji-Seok Kim (21287672)

“…The 4-week AngII group exhibited significantly increased fibrosis (~2-fold vs. Veh, p < 0.01), elevated TGF-β and iNOS expression, and disrupted autophagic flux, including increased LC3-II/I ratio and ATG expression, alongside decreased p62 levels. …”

Transmission electron microscopy (TEM) photographs. by Jingjing Chen (293564)

“…<b>E</b>: At 3 weeks after penetrating injury, collagenous fiber distribution was irregular and myofibroblasts increased further in the stroma while the defective EBM regenerated (Magnification=30000). <b>F-H</b>: One to 3 months after injury, collagenous fiber distribution became more and more regular, myofibroblasts decreased; the EBM was progressively restructured (Magnification=30000). …”

Applications of Human Biostasis in Crewed Space Exploration by Josh Universe (21186797)

“…<p dir="ltr">Applications of Human Biostasis for Crewed Space Exploration is a presentation by Josh Universe, the Founder of the International Biohacking Community and Transhumanist Council, a science communicator, and a scientist-astronaut candidate. …”

The evolution of inharmonicity and noisiness in contemporary popular music by Emmanuel Deruty (20394899)

“…From 1961 to 1972, inharmonicity in popular music, initially only slightly higher than in orchestral music, increased significantly. Between 1972 and 1986, this rise in inharmonicity was accompanied by an increase in noise, but since 1986, both inharmonicity and noise have moderately decreased. …”

SEAwise report on the impact of socioeconomic effects of fisheries management adapted according to input from review workshops by Isabella Bitetto (20145735)

“…Lusitanian fish species and cephalopods are already contributing significantly to North Sea fisheries revenues, although boreal species remain dominant, particularly in ICES areas 27.4 and 27.3.A. …”

Table 4_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc by Md Shoykot Jahan (22776341)

“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…”

Table 3_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.doc by Md Shoykot Jahan (22776341)

“…Increased miR-17-5p suppressed MAP3K2 expression and attenuated MAPK signaling, reducing phosphorylation of ERK, JNK, and p38. This resulted in decreased production of inflammatory mediators (TNF-α, IL-6, IL-1β), reduced iNOS and ROS levels, and impaired bacterial clearance.…”