Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant a » significant _ (Expand Search), significant gap (Expand Search), significant all (Expand Search)
significant i » significant _ (Expand Search), significant co (Expand Search), significant 17 (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant a » significant _ (Expand Search), significant gap (Expand Search), significant all (Expand Search)
significant i » significant _ (Expand Search), significant co (Expand Search), significant 17 (Expand Search)
-
7941
Supplementary file 1_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
-
7942
-
7943
Table 1_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx
Published 2024“…Two SNPs and one haplotype block of the SPP1 gene and four SNPs and one haplotype block of the NCAPG gene were obtained by amplification, sequencing and association analysis, and all six SNPs were located in the exon region. …”
-
7944
Supplementary file 1_tRF-1:28-Val-CAC-2 promotes the development of nasopharyngeal cancer by targeting EPHB2.doc
Published 2025“…At a mechanistic level, these effects were related to the control of EPHB2 gene expression by tRF-1:28 Val-CAC-2, thereby shaping the survival and malignancy of the cells.…”
-
7945
Table1_Astragaloside IV Alleviates Tacrolimus-Induced Chronic Nephrotoxicity via p62-Keap1-Nrf2 Pathway.DOCX
Published 2025“…The expression of fibrosis-related proteins, including TGF-β<sub>1</sub>, Collagen I and α-SMA, were also decreased by AS-IV. …”
-
7946
Table1_Astragaloside IV Alleviates Tacrolimus-Induced Chronic Nephrotoxicity via p62-Keap1-Nrf2 Pathway.DOCX
Published 2025“…The expression of fibrosis-related proteins, including TGF-β<sub>1</sub>, Collagen I and α-SMA, were also decreased by AS-IV. …”
-
7947
Table 1_Trends in physical fitness among polish children and adolescents.docx
Published 2025“…Background<p>Human health, with physical fitness as one of its key indicators, is characterized by a dynamic nature. …”
-
7948
Renal function and risk of dementia: a Mendelian randomization study
Published 2024“…</p> <p>The findings indicate a significant correlation between each unit increase in cystatin C-based estimated glomerular filtration rate (eGFR-cys) levels was significantly associated with a reduction in the incidence of late-onset Alzheimer’s disease (LOAD) (IVW: OR = 0.35, 95% CI: 0.13–0.91, <i>p</i> = 0.031). …”
-
7949
Supplementary Material for: Quality of Life After Alloplastic vs. Autologous Breast Reconstruction: 'The Influence of Patient Characteristics on Outcomes'
Published 2025“…Conclusion: This study confirms that even when adjusted for confounders, scores on two QoL sub-scales autologous breast reconstruction patients score significantly higher over time. Although autologous reconstruction remained superior regarding “Satisfaction with Breasts”, scores decreased in autologous reconstruction patients when they were depressed at baseline, underwent radiotherapy, had a history of breast cancer, or faced major complications.…”
-
7950
<b>Three-year follow-up after antiviral treatment in new-onset type 1 diabetes. Results from the Diabetes Virus Detection and Intervention trial.</b>
Published 2025“…<p dir="ltr"><b>Objective</b></p><p dir="ltr">In the Diabetes Virus Detection and Intervention trial, antiviral treatment with pleconaril and ribavirin was shown to decrease the decline in endogenous C-peptide one year after diagnosis of type 1 diabetes in children and adolescents compared to placebo. …”
-
7951
Data Sheet 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.xlsx
Published 2025“…Interestingly, NcGRA7 formed a complex with the prohibitins PHB1 and PHB2. Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…”
-
7952
Table 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.docx
Published 2025“…Interestingly, NcGRA7 formed a complex with the prohibitins PHB1 and PHB2. Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…”
-
7953
-
7954
Data Sheet 1_Impact of self-reported SARS-CoV-2 antibody positivity on cardiac structure and function: findings from UK Biobank CMR cohort.docx
Published 2025“…Over an average follow-up period of 110 days, significant decreases in CO and CI were observed in the paired participants. …”
-
7955
Image 4_ZKSCAN3 promotes ovarian cancer cell proliferation by increasing HSPB1 expression.pdf
Published 2025“…Through RNA-Seq and chromatin immunoprecipitation (ChIP)-seq, HSPB1 is identified as a target gene of ZKSCAN3. HSPB1 expression is significantly decreased upon suppressing ZKSCAN3 expression. …”
-
7956
Image 3_ZKSCAN3 promotes ovarian cancer cell proliferation by increasing HSPB1 expression.pdf
Published 2025“…Through RNA-Seq and chromatin immunoprecipitation (ChIP)-seq, HSPB1 is identified as a target gene of ZKSCAN3. HSPB1 expression is significantly decreased upon suppressing ZKSCAN3 expression. …”
-
7957
Image 2_ZKSCAN3 promotes ovarian cancer cell proliferation by increasing HSPB1 expression.pdf
Published 2025“…Through RNA-Seq and chromatin immunoprecipitation (ChIP)-seq, HSPB1 is identified as a target gene of ZKSCAN3. HSPB1 expression is significantly decreased upon suppressing ZKSCAN3 expression. …”
-
7958
Cued-attention is mediated by a cholinergic HDB to SAC circuit.
Published 2025“…<p>(A) Schematic of induced expression of DREADDi in SACs of <i>OMP-tTA; tetO-GCaMP2; DAT-Cre</i> animals and imaging of glomerular activity using GCaMP2. …”
-
7959
Image 2_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif
Published 2025“…</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”
-
7960
Image 6_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif
Published 2025“…</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …”