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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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significant i » significant _ (Expand Search), significant co (Expand Search), significant 17 (Expand Search)
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8221
Data Sheet 3_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf
Published 2025“…It ameliorated MAMs ultrastructure and function, enhancing CypD, MCU, Sig-1R, and NOGO-B expression while reducing IP3R2, GRP75, and VDAC1. in vitro, YQHX significantly increased viability, reduced oxygen-glucose deprivation-induced mPTP opening and Ca<sup>2+</sup> levels, upregulated CypD, MCU, Sig-1R, and NOGO-B, and downregulated IP3R2, GRP75, and VDAC1. …”
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8222
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8223
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8224
Inc exhibits key properties of a Cul3 adaptor in neurons in vivo.
Published 2025“…Neuronal <i>Cul3</i> RNAi decreases <i>Cul3</i> transcript levels but does not significantly alter those of <i>inc</i>. …”
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8225
Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx
Published 2025“…TCF3 knockdown significantly attenuated these EMT changes and increased autophagy markers, as evidenced by decreased P62 levels (p < 0.01) and increased LC3-II/I ratio (p < 0.001) and Beclin-1 expression (p < 0.01). …”
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8226
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8227
Supplemental data for "<b>Kidney cell response to acute cardiorenal and isolated kidney ischemia-reperfusion injury</b>" in Physiological Genomics
Published 2024“…Based on this, we created a novel score to capture the dedifferentiation state of each kidney cell population and found that certain epithelial cell populations, such as the PT S1 and S2 segments, as well as the distal convoluted tubule, exhibited significant dedifferentiation response. …”
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8228
Image1_Hemopexin alleviates sterile inflammation in ischemia-reperfusion-induced lung injury.tif
Published 2024“…Introduction<p>Pulmonary ischemia-reperfusion (IR) injury (IRI) plays a significant role in various lung disorders and is a key factor in the development of primary graft dysfunction following lung transplantation. …”
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8229
Data Sheet 1_ESAT-6 protein suppresses allograft rejection by inducing CD4+Foxp3+ regulatory T cells through IκBα/cRel pathway.docx
Published 2025“…ESAT-6 augmented the percentage of CD4<sup>+</sup>Foxp3<sup>+</sup> Tregs, whereas it decreased the frequency of Th1 and CD4<sup>+</sup>/CD8<sup>+</sup> effector T cells in spleen and lymph nodes (LNs) posttransplantation. …”
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8230
Hemodynamic mechanisms underlying orthostatic hypotension in stroke survivors: a cross-sectional study
Published 2025“…These individuals demonstrated significantly greater orthostatic cardiac index increases (F<sub>(5,105)</sub> = 2.75, <i>p</i> = 0.023, partial η<sup>2</sup> = 0.126) and more pronounced orthostatic total peripheral resistance index decreases (F<sub>(5,105)</sub> = 4.19, <i>p</i> = 0.002, partial η<sup>2</sup> = 0.166) than those without orthostatic hypotension.…”
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8231
Personality traits in people with multiple sclerosis: A systematic review and meta-analysis
Published 2025“…Additionally, higher Neuroticism was significantly linked to increased anxiety (<i>r</i> = 0.78), depression (<i>r</i> = 0.53), and fatigue (<i>r</i> = 0.35), and Conscientiousness was significantly correlated with decreased Expanded Disability Status Scale (EDSS) (<i>r</i> = −0.21) and Symbol Digit Modalities Test (SDMT) (<i>r</i> = 0.13). …”
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8232
Data Sheet 1_Cardioprotective effects of the electrolyte solution sterofundin and the possible underlying mechanisms.pdf
Published 2025“…Moreover, RNA-seq analysis demonstrated that SF caused the gene expression profile of MI mice to shift toward that of sham mice, with a significant decrease in apoptosis-, ROS-, and inflammation-associated gene enrichment. …”
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8233
Supplementary file 4_Breast cancer burden in the United States (1990–2021) with a 15-year forecast: a comprehensive analysis based on the global burden of disease 2021.gif
Published 2025“…Objective<p>Breast cancer (BC) is one of the most common cancers globally, placing a significant social burden. …”
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8234
Data Sheet 4_Breast cancer burden in the United States (1990–2021) with a 15-year forecast: a comprehensive analysis based on the global burden of disease 2021.csv
Published 2025“…Objective<p>Breast cancer (BC) is one of the most common cancers globally, placing a significant social burden. …”
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8235
Supplementary file 2_Breast cancer burden in the United States (1990–2021) with a 15-year forecast: a comprehensive analysis based on the global burden of disease 2021.gif
Published 2025“…Objective<p>Breast cancer (BC) is one of the most common cancers globally, placing a significant social burden. …”
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8236
Supplementary file 3_Breast cancer burden in the United States (1990–2021) with a 15-year forecast: a comprehensive analysis based on the global burden of disease 2021.gif
Published 2025“…Objective<p>Breast cancer (BC) is one of the most common cancers globally, placing a significant social burden. …”
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8237
Data Sheet 3_Breast cancer burden in the United States (1990–2021) with a 15-year forecast: a comprehensive analysis based on the global burden of disease 2021.csv
Published 2025“…Objective<p>Breast cancer (BC) is one of the most common cancers globally, placing a significant social burden. …”
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8238
Data Sheet 2_Breast cancer burden in the United States (1990–2021) with a 15-year forecast: a comprehensive analysis based on the global burden of disease 2021.csv
Published 2025“…Objective<p>Breast cancer (BC) is one of the most common cancers globally, placing a significant social burden. …”
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8239
Data Sheet 1_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.pdf
Published 2025“…</p>Results<p>NRIR knockdown reduced RSAD2 expression and suppressed activation of the NF-κB pathway, consequently decreasing inflammatory cytokines and M1 macrophage-associated cytokine expression in THP-1 macrophages. …”
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8240
Table 1_Characterization of the airway microbiome in preterm infants with bronchopulmonary dysplasia.doc
Published 2025“…Previous studies have indicated a significant association between the pulmonary microbiome and various respiratory diseases. …”