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19621
<b>Metabolic Improvements with Tirzepatide in Lipodystrophy: A Novel Option?</b>
Published 2025“…Side effects were limited to benign gastrointestinal symptoms. …”
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19622
Image 1_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…</p>Results<p>Melatonin treatment significantly reduced ZIKV and DENV-4 replication and the associated inflammatory response in U87-MG cells. …”
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19623
Table 3_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …”
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19624
Image 2_Inhibition of CRM1 reverses hypoxia-driven chemoresistance in acute myeloid leukemia via overcoming HIF-1α-mediated lysosomal sequestration.jpeg
Published 2025“…Inhibition of P-gp or HIF-1α reversed these effects. CRM1 and PHD2 expression increased under hypoxia, but nuclear accumulation of PHD2 decreased. …”
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19625
Image 3_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…</p>Results<p>Melatonin treatment significantly reduced ZIKV and DENV-4 replication and the associated inflammatory response in U87-MG cells. …”
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19626
Image 2_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…</p>Results<p>Melatonin treatment significantly reduced ZIKV and DENV-4 replication and the associated inflammatory response in U87-MG cells. …”
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19627
A platform for the rapid screening of equine immunoglobins F (ab)2 derived from single equine memory B cells able to cross-neutralize to influenza virus
Published 2024“…Antibody H81 exhibited the highest cross neutralizing activities against EIV strains <i>in vitro</i>. Furthermore, it effectively protected EIV-challenged mice, resulting in significantly improved survival, reduced pulmonary inflammation and decreased viral titers. …”
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19628
Table 2_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …”
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19629
Characteristics of specialists at day centers.
Published 2025“…The intervention group showed significantly reduced weight (median; baseline 1, post-intervention 0.975, follow-up 0.983, p < 0.001), and slightly reduced waist circumference (median; baseline 1, post-intervention 0.975, follow-up 0.975, p = 0.226); however, the control group showed no change. …”
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19630
Data Sheet 1_A novel bioactive peptide-peptoid hybrid of alpha-calcitonin gene-related peptide protects against pressure-overload induced heart failure.docx
Published 2025“…NMEG-CGRP administration significantly attenuated these TAC-induced adverse cardiac effects in the HF mice.…”
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19631
<b>The Bacterial OMP Amyloids Modulate</b><b> </b><b>α</b><b>-Synuclein and Amyloid-</b><b>β</b><b> </b><b>Aggregation</b>
Published 2025“…In contrast, amyloid-β fibrils showed more extensive structural changes, with modifications to both the "fuzzy coat" and β-sheet core, accompanied by decreased clustering tendency and significantly reduced toxicity for mammalian neuroblastoma and epithelial adenocarcinoma cell lines. …”
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19632
Data Sheet 1_Preoperative remote consultation for a green bariatric surgery: can telemedicine be safe for patients and sustainable for the environment?.pdf
Published 2025“…</p>Conclusion<p>Telemedicine in bariatric surgery is safe, effective, and significantly reduces environmental impact. …”
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19633
Table 7_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …”
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19634
Supplementary file 1_ZnO nanoparticles induce acute arrhythmia and heart failure in mice by disturbing cardiac ion channels.pdf
Published 2025“…Mechanistically, exposure to ZnO NPs did not significantly affect the IK1, but it markedly decreased I<sub>Na</sub> and I<sub>Ca−L</sub> currents, resulting in a reduced amplitude and shortened duration of the action potential in cardiomyocytes. …”
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19635
The Dataset used for Tables 1 and 3.
Published 2025“…The intervention group showed significantly reduced weight (median; baseline 1, post-intervention 0.975, follow-up 0.983, p < 0.001), and slightly reduced waist circumference (median; baseline 1, post-intervention 0.975, follow-up 0.975, p = 0.226); however, the control group showed no change. …”
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19636
Table 5_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis...
Published 2025“…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …”
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19637
The prognostic value of the neutrophil-percentage-to-albumin ratio for all-cause and cardiovascular mortality in chronic kidney disease stages G3a to G5: insights from NHANES 2003–...
Published 2025“…Identifying laboratory-accessible, cost-effective markers that can effectively predict the prognosis of CKD stages G3a to G5 is crucial.…”
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19638
Data Sheet 1_Renewable energy consumption optimization allocation strategy for a regional microgrid based on a shared energy storage mechanism.zip
Published 2025“…This indicates that the proposed method for constructing a bilayer optimization configuration can effectively consider the economic consumption of new energy and significantly improve the economic operation of shared energy storage stations and regional microgrids.…”
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19639
Supplementary file 3_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
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19640
Supplementary file 4_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”