Showing 1 - 20 results of 173 for search '(( significant decrease decrease ) OR ( ((significant based) OR (significant binding)) decrease ))~', query time: 0.41s Refine Results
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    Synthesis and Preclinical Evaluation of Novel <sup>99m</sup>Tc-Labeled FR-Targeting Agents with Satisfactory Imaging Contrast and Reduced Renal Uptake by Junhong Feng (11835903)

    Published 2025
    “…The results of both in vitro cell and in vivo normal mice biodistribution studies demonstrated specific binding of eight complexes to the FR. Among them, [<sup>99m</sup>Tc]Tc-DProFA-L1 exhibited lower off-target uptake and high tumor uptake in tumor-bearing mice, and significant inhibition in the biodistribution and SPECT/CT imaging study. …”
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