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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant changes » significant challenge (Expand Search)
significant cause » significant change (Expand Search), significant gap (Expand Search), significant increase (Expand Search)
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20961
Data Sheet 1_Genetic knockdown of DYRK1A attenuates cognitive impairment, Aβ pathology, tauopathy and neuroinflammatory responses in mouse models of AD.docx
Published 2025“…</p>Results and discussion<p>In WT mice, hippocampal DYRK1A overexpression significantly reduced short-term spatial/recognition memory and SynGAP expression while increasing p-P38 levels. …”
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20962
Table 1_Bifidobacterium compound preparations as a supplementary treatment for severe ischemic stroke: a systematic review and meta-analysis.docx
Published 2025“…Regarding neurological function, the BCP combination group significantly increased the Glasgow Coma Scale score (MD = 1.86, 95% CI 1.17 to 2.56, p < 0.00001) and decreased the National Institutes of Health Stroke Scale score (MD = −2.17, 95% CI −3.35 to −0.99, p = 0.0003). …”
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20963
Image 2_Volumetric modulated arc therapy total body irradiation improves toxicity outcomes compared to 2D total body irradiation.jpeg
Published 2024“…However, there is limited evidence of whether improved organ sparing translates to decreases in toxicities and how its toxicities compare to those of the 2D technique. …”
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20964
Image 1_Volumetric modulated arc therapy total body irradiation improves toxicity outcomes compared to 2D total body irradiation.jpeg
Published 2024“…However, there is limited evidence of whether improved organ sparing translates to decreases in toxicities and how its toxicities compare to those of the 2D technique. …”
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20965
Table 2_IFN-treated macrophage-derived exosomes prevents HBV-HCC migration and invasion via regulating miR-106b-3p/PCGF3/PI3K/AKT signaling axis.docx
Published 2024“…Significantly increased expression of miR-106b-3p and decreased expression of HBsAg and HBV DNA were observed in Huh7-C2/B3 cells treated with IFN-exo. …”
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20966
Presentation 1_Baduanjin exercise improves functional capacity and cardiovascular function in older adults with cardiovascular diseases: a systematic review and meta-analysis.pdf
Published 2025“…What's more, it also decreased MLHFQ (MD: −7.00, 95% CI: −9.54 to −4.45, p = 0.0003, I<sup>2</sup> = 79%).…”
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20967
Supplementary file 3_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.docx
Published 2025“…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …”
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20968
Supplementary file 1_Identifying early blood glucose trajectories in sepsis linked to distinct long-term outcomes: a K-means clustering study with external validation.docx
Published 2025“…Conversely, patients with a “high-stable” trajectory (HR: 1.61, 95% CI: 1.35-1.92, P < 0.001) and those exhibiting unstable trends had significantly higher mortality risks (“high-decreasing”, HR: 1.38, 95% CI: 1.16-1.65, P < 0.001; “moderate-increasing”, HR: 1.37, 95% CI: 1.18-1.60, P < 0.001). …”
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20969
Supplementary file 2_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.zip
Published 2025“…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …”
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20970
Data Sheet 1_A novel short-course, low-intensity blood-flow-restricted exercise (BFRE) regimen to study satellite cell function in critical illness survivors with sustained muscle...
Published 2025“…In controls, satellite cell content and MuRF1 transcript expression were significantly higher (1.53 ± 0.30- and 1.34 ± 0.31-fold difference, respectively) and myostatin transcript expression was significantly lower (0.58 ± 0.31-fold difference) in BFRE-trained versus untrained VL. …”
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20971
Table1_Vermicompost application improves leaf physiological activity, 2-acetyl-1-pyrroline, and grain yield of fragrant rice through efficient nitrogen assimilation under Cd stress...
Published 2024“…In addition, VC application significantly (p < 0.05) decreased the Cd uptake and accumulation in rice plants. …”
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20972
Supplementary file 1_Association of antenatal dexamethasone administration timing with outcomes in preterm infants in a low- and middle-income country.docx
Published 2025“…No other secondary outcomes differed significantly.</p>Conclusion<p>Dexamethasone administration within 24 h before delivery did not reduce mortality but significantly decreased the risk of severe NEC. …”
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20973
Supplementary file 1_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.zip
Published 2025“…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …”
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20974
Da-Yuan-Yin decoction suppresses NETs formation, inhibits the IL-23/JAK2/STAT3 signalling pathway, and modulates metabolic profiles and gut microbiota composition in damp-heat synd...
Published 2025“…Complete blood count (CBC), blood biochemistry, short-chain fatty acids (SCFAs), gut microbiota composition in the colon, and metabolites in the cecum were analyzed.</p> <p>DYY significantly reduced symptom scores and decreased CRP level, while also regulating parameters in CBC and biochemical profiles. …”
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20975
Matched data.
Published 2025“…</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …”
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20976
Phage–antibiotic interactions are determined by the antibiotic, not the phage.
Published 2025“…Nitrofurantoin shows significantly more synergistic interactions than doxycycline (<i>p</i> = 0.008, Wilcoxon signed-rank test). …”
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20977
Data Sheet 2_Identification of potential miRNA biomarkers for neurobrucellosis diagnosis.pdf
Published 2025“…Among these, four common miRNAs (miR-342-3p, miR-576-5p, miR-15b-5p and miR-499a-5p) were significantly elevated in the infection group compared to controls in both the in-house and validation cohorts. …”
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20978
Image 2_A natural PCID2-Targeting compound suppresses hepatocellular carcinoma progression: evidence from structure-based discovery and biological evaluation.jpeg
Published 2025“…Mechanistically, β-PGG decreased PCID2 expression and downregulated Cyclin D1 and CDK6. …”
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20979
Table 1_Executive functions in post-traumatic stress disorder: their relation to PTSD severity and daily functioning.pdf
Published 2025“…The VAP-S 2 revealed difficulties in executive functions, expressed as higher impulsivity, lower strategy use, and decreased performance efficiency while shopping in the virtual supermarket. …”
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20980
Supplementary file 1_Bone marrow adipose tissue expansion and bone loss in experimental chronic kidney disease is independent of altered bone marrow stromal cell lineage determinat...
Published 2025“…After 5-weeks’ induction, trabecular bone microarchitecture including bone mineral density was compromised whereas cortical bone area and thickness were decreased in CKD tibiae after 3- and 5-weeks’ induction. …”