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significant changes » significant challenge (Expand Search)
significant cause » significant change (Expand Search), significant gap (Expand Search), significant increase (Expand Search)
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18041
Table 1_5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation.docx
Published 2025“…Introduction<p>Acute lung injury (ALI) induced by lipopolysaccharide (LPS) is a significant medical condition characterized by severe pulmonary inflammation and tissue damage. …”
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18042
DataSheet1_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip
Published 2025“…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …”
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18043
Supplementary Material for: The role of reactive oxygen species in the pathogenesis of alopecia areata: a systematic review and meta-analysis.
Published 2025“…Background: Alopecia areata (AA) is a T-cell-mediated autoimmune disease that significantly impacts patient quality of life. The breakdown of hair follicle immune privilege underlies AA pathogenesis. …”
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18044
Data Sheet 2_Astragalus polysaccharide modulates the gut microbiota and metabolites of patients with major depressive disorder in an in vitro fermentation model: a pilot study.xlsx
Published 2025“…APS fermentation increased the abundance of Bifidobacterium and decreased the abundance of Lachnoclostridium (p < 0.05). …”
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18045
Model comparison experimental results.
Published 2025“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”
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18046
DataSheet3_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip
Published 2025“…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …”
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18047
Data Sheet 1_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.pdf
Published 2025“…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …”
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18048
Data Sheet 1_Acupoint catgut embedding alleviates experimental autoimmune encephalomyelitis by modulating neuroinflammation and potentially inhibiting glia activation through JNK a...
Published 2025“…In ACE-treated mice, EAE disease severity was significantly ameliorated, along with improvements in anxiety-like behaviors and reduced inflammation and demyelination. …”
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18049
Image 1_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.tiff
Published 2024“…</p>Conclusion<p>These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.…”
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18050
Table 1_Cross-education: motor unit adaptations mediate the strength increase in non-trained muscles following 8 weeks of unilateral resistance training.xlsx
Published 2025“…These gains were accompanied by significant decreases in motor unit recruitment thresholds (p < 0.01) and higher net discharge rate (i.e., gain in discharge rate from recruitment to peak) following intervention (p < 0.05). …”
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18051
Slicing aided hyper inference algorithm.
Published 2025“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”
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18052
Table 2_Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer.xlsx
Published 2025“…A higher immune infiltration rate and lower IC50 values of anticancer drugs were significant in the high-risk group. In cellular experiments, Following MAN1B1 knockdown, in cell assays, the colony formation, migration, and invasion ability of HCT116 and HT29 cell lines decreased.…”
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18053
Data Sheet 3_Genome-wide identification of GDPD gene family in foxtail millet (Setaria italica L.) and functional characterization of SiGDPD14 under low phosphorus stress.docx
Published 2025“…Under low phosphorus stress, the expression levels of SiGDPD3 and SiGDPD14 significantly increased, while SiGDPD1, SiGDPD5, SiGDPD6, and SiGDPD11 showed significant decreases.To identify the function of SiGDPD14, an over-expressed transgenic Arabidopsis was generated. …”
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18054
Table 2_Global, regional and national patterns and gender disparity of intraocular foreign bodies from 1990 to 2021.doc
Published 2025“…The age-standardized DALYs rates of males were significantly higher than those of females in all five SDI groups (p < 0.001) in 2021. …”
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18055
Image 2_Body Mass Index mediates the associations between dietary approaches to stop hypertension and obstructive sleep apnea among U.S. adults.tiff
Published 2024“…</p>Conclusion<p>These findings suggested that DASH decreased OSA risk, which was possibly and partly mediated by BMI.…”
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18056
Dynamic system state in demand scenarios 3.
Published 2025“…<div><p>Capturing congestion propagation among different facilities at intersections in dynamic stochastic traffic environments poses significant challenges, particularly under oversaturated conditions. …”
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18057
Improved YOLOv10 network structure.
Published 2025“…The experimental results demonstrate that when compared to YOLOv10, S-YOLOv10-ASI shows significant improvements across various metrics. Specifically, Bounding Box Regression Loss decreases by over 30% in the training set, while Classification Loss and Bounding Box Regression Loss drop by more than 60% in the validation set. …”
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18058
Supplementary file 2_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.pdf
Published 2025“…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…”
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18059
Image 2_Genome-wide identification of GDPD gene family in foxtail millet (Setaria italica L.) and functional characterization of SiGDPD14 under low phosphorus stress.png
Published 2025“…Under low phosphorus stress, the expression levels of SiGDPD3 and SiGDPD14 significantly increased, while SiGDPD1, SiGDPD5, SiGDPD6, and SiGDPD11 showed significant decreases.To identify the function of SiGDPD14, an over-expressed transgenic Arabidopsis was generated. …”
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18060
Table 1_Singing for memory: neural and cognitive effects of a choral intervention in older adults.docx
Published 2025“…</p>Results<p>Partial correlation analyses, adjusting for age and cognitive ability, showed significant improvements in episodic memory following both the control period (T1-T2) and the choir intervention (T2-T3), but only the latter scaled with rehearsal attendance. …”