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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant cause » significant change (Expand Search), significant changes (Expand Search), significant increase (Expand Search)
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19761
Image 2_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin...
Published 2025“…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”
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19762
Table 2_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin...
Published 2025“…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”
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19763
Friedman statistic and p-value across iterations.
Published 2025“…However, the model’s robustness decreased when the data structure was shuffled, indicating limited generalization to unseen data. …”
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19764
YOLOv8n detection results diagram.
Published 2025“…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”
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19765
Glutamate dehydrogenase 2 is required for virulence by facilitating fungal growth in the host hemocoel
Published 2025“…Loss of <i>MrGDH2</i> function resulted in significantly reduced virulence during both cuticle-passing and cuticle-bypassing infections but did not affect appressorium formation or cuticle penetration. …”
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19766
Image 1_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif
Published 2025“…</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …”
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19767
Dynamic window based median filtering algorithm.
Published 2025“…The computational complexity of the improved model decreased dramatically, but the average classification accuracy was only 1.6% lower than that before the improvement. …”
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19768
Image 7_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif
Published 2025“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
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19769
Table 1_Correlation between changes of amino acid spectrum and alopecia in patients with obesity undergoing bariatric surgery: a prospective cohort study.docx
Published 2025“…</p>Results<p>Among 67 patients analyzed, LSG significantly decreased serum concentrations of arginine, alanine, threonine, glutamic acid, branched-chain amino acids (valine, isoleucine, leucine), and aromatic amino acids (tyrosine, phenylalanine, tryptophan) (p < 0.05), while serine and glycine increased (p < 0.05). …”
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19770
Data for: Drought and temperature stresses impact pollen production and autonomous selfing in a California wildflower, Collinsia heterophylla
Published 2025“…In nature, such responses will likely reduce available nutrition for pollinators through decreased flower and pollen production.</p><p>The included data file can be opened with any spreadsheet software including MS Excel or Google Sheets.…”
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19771
Image 4_Photon budgets and the relative effects of CDOM and pigment absorptions on primary production along a coastal salinity gradient.jpeg
Published 2025“…The absorption by CDOM and detritus decreased with increasing salinity, while phytoplankton absorption followed a seasonal succession. …”
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19772
YOLOv8n-BWG model structure diagram.
Published 2025“…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…”
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19773
Image 2_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif
Published 2025“…</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …”
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19774
Image 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.jpeg
Published 2025“…</p>Conclusion<p>Our findings elucidate the molecular mechanism that PCP4 downregulation promotes PCa progression via Ca<sup>2+</sup>/CAMKK2/AMPK/AR pathway, highlighting its significance in CRPC development.</p>…”
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19775
Navigation error analysis.
Published 2025“…Results show that SIDFM reduces navigation errors by 12.09% at low acceleration and 11.43% at high acceleration while also significantly decreasing positioning errors. These improvements enhance the stability, precision, and safety of AGVs in dynamic manufacturing environments. …”
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19776
Supplementary file 1_Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machi...
Published 2025“…Recovery analysis showed significantly reduced adaptive immune cells at 1 month, with partial recovery by 3 and 6 months. …”
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19777
Image 6_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
Published 2025“…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…”
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19778
Image 2_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif
Published 2024“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”
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19779
Base-case results.
Published 2024“…Clinical findings have showed that deprescribing service significantly decreased inappropriate PPIs utilization. …”
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19780
Image 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.jpeg
Published 2025“…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …”