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significant change » significant changes (Expand Search), significant challenge (Expand Search), significant challenges (Expand Search)
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141
Supplementary file 1_Assessment of suitability evaluation for Ficus altissima blume ancient trees in different climatic environments in Guangxi, China.docx
Published 2025“…</p>Methods<p>To address this gap, using machine learning and species distribution models, we analyzed their distribution patterns and habitat suitability changes under current and future climate scenarios, incorporating 33 climatic, topographic, and soil-related driving factors.…”
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142
Image 5_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tiff
Published 2025“…<p>One of the major consequences of schistosomiasis is its impact on brain function, and despite its severity, the underlying mechanism(s) remain inadequately understood, highlighting a knowledge gap in the disease. The symptoms can vary from headaches to profound cognitive impairment. …”
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143
Image 2_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
Published 2025“…<p>One of the major consequences of schistosomiasis is its impact on brain function, and despite its severity, the underlying mechanism(s) remain inadequately understood, highlighting a knowledge gap in the disease. The symptoms can vary from headaches to profound cognitive impairment. …”
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144
Determinants of lipid lowering therapy intensification in very high risk patients with dyslipidaemia eligible for PCSK9 monoclonal antibodies: 1-year outcomes of the PERI-DYS study
Published 2025“…This suggests an underutilisation of available treatments, highlighting a gap in the management of high CV risk patients.</p>…”
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145
Table 4_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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146
Table 3_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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147
Table 1_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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148
Table 5_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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149
Table 2_Global, region and country burden of osteoarthritis at different sites in middle-aged and elderly populations from 1990 to 2021: a systematic analysis of the 2021 global bu...
Published 2025“…From 1990 to 2021, the inequality in overall OA burden between countries had decreased. The absolute inequality gap for hand OA had narrowed the most significantly (45.3%), which followed by knee OA (11.9%), while the inequality gap for hip OA has slightly increased.…”
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150
raw data
Published 2025“…<p dir="ltr"><b>Introduction and methods: </b>Vegetation disturbance intensity serves as a critical determinant of changes in soil nutrients and microbial communities. …”
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151
Image 2_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.pdf
Published 2025“…The estimated annual percentage change (EAPC) and corresponding 95% confidence intervals (CIs) were calculated, with positive EAPC values indicating an increasing trend and negative values indicating a decreasing trend. …”
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152
Image 1_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.tif
Published 2025“…The estimated annual percentage change (EAPC) and corresponding 95% confidence intervals (CIs) were calculated, with positive EAPC values indicating an increasing trend and negative values indicating a decreasing trend. …”
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153
Table 2_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.docx
Published 2025“…The estimated annual percentage change (EAPC) and corresponding 95% confidence intervals (CIs) were calculated, with positive EAPC values indicating an increasing trend and negative values indicating a decreasing trend. …”
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154
Table 1_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.docx
Published 2025“…The estimated annual percentage change (EAPC) and corresponding 95% confidence intervals (CIs) were calculated, with positive EAPC values indicating an increasing trend and negative values indicating a decreasing trend. …”
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155
Supplementary file 1_Effects of different urban vegetation cover and green space types on soil greenhouse gas emissions and carbon sequestration.docx
Published 2025“…The annual increase of SOC in residential and streets was notably lower than that in parks green spaces, by 9.59% and 15.20%, respectively, indicating significant differences. This suggests that soil carbon sequestration capacity is highly responsive to changes in vegetation coverage and green space types, with WSOC, NH<sub>4</sub><sup>+</sup>-N, and pH identified as the primary factors influencing the greenhouse gas flux in the three soils. …”
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156
Data Sheet 1_Increased vegetation disturbance intensity reduces soil nutrients while enhancing microbial network interactions.pdf
Published 2025“…Introduction and methods<p>Vegetation disturbance intensity serves as a critical determinant of changes in soil nutrients and microbial communities. …”
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157
Data Sheet 1_Seaweed (Porphyra) cultivation enhances production of autochthonous refractory dissolved organic matter in coastal ecosystems.docx
Published 2025“…Dissolved organic carbon (DOC) concentration was significantly elevated during the cultivation versus non-cultivation period, while particulate organic carbon (POC) concentration decreased, thereby resulting in a higher DOC/POC ratio in the water column. …”
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158
Data Sheet 1_Impact of individualized and structured aerobic exercise on clinical outcomes in pediatric congenital heart diseases with post-surgical rehabilitation: a meta-analysis...
Published 2025“…While exercise-based rehabilitation is highly recommended, significant knowledge gaps persist regarding the long-term impact of structured exercise on diverse CHD subtypes, optimal modalities, and standardized protocols for implementation. …”
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159
DNA barcodes of 38 plant species
Published 2025“…However, increased stocking rates can alter the composition and structure of plant communities, thereby impacting the food resources and trophic niche of grasshoppers. Currently, significant gaps exist in research on how the trophic niche of grasshoppers changes under different stocking rates. …”
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160
Data Sheet 4_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf
Published 2025“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”