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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant changes » significant challenge (Expand Search)
significant based » significant cause (Expand Search), significant barrier (Expand Search), significant burden (Expand Search)
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21141
Table4_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg
Published 2024“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”
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21142
Supporting data for “<b>Human Lipocalin-2 Variants: Therapeutic Evaluations</b>”
Published 2024“…</p><p dir="ltr">Following a high-fat diet, our findings demonstrated that C87A levels were significantly elevated in cardiac and epididymal white adipose tissue (eWAT). …”
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21143
Table 1_Molecular, biofilm and motility characterization of Acinetobacter baumannii isolated from a neonatal intensive care unit at a children’s hospital in South China.xlsx
Published 2025“…Biofilm formation of ST1959 was significantly enhanced by gentamicin but inhibited by levofloxacin. …”
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21144
Table 2_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.doc
Published 2025“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”
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21145
Image 4_Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7...
Published 2025“…</p>Results<p>Metformin significantly reduced periapical bone destruction on postoperative days 21 and 28, and decreased the number of osteoclasts on the periapical alveolar bone on postoperative day 28. …”
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21146
Data Sheet 1_Evaluation of the epidemiological and economic impact of the ADLIFE intervention on medium- to long-term in patients with advanced chronic disease.pdf
Published 2025“…Emergency visits and consultations with primary care professionals decreased significantly, while specialist consultations increased. …”
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21147
Table2_Identification of telomere-related lncRNAs and immunological analysis in ovarian cancer.xlsx
Published 2024“…PTPRD-AS1 knockdown decreased the proliferation, cloning, and migration of CAOV3 cells.…”
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21148
Essential model parameters.
Published 2024“…This study underscores the significance of the COVID-19 vaccine booster policy. …”
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21149
Image 2_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff
Published 2025“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”
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21150
Image 3_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png
Published 2025“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”
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21151
Table 3_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.xlsx
Published 2025“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”
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21152
Table 4_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx
Published 2025“…</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”
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21153
Table 1_Effects of folic acid with vitamin B12/vitamin B6 intervention on serum homocysteine metabolism and complications in patients with type 2 diabetes: a systematic review and...
Published 2025“…Supplementation with folic acid plus vitamin B12 (SMD = −2.77, 95% CI [−3.23, −2.30], P < 0.0001) significantly reduced serum homocysteine levels and decreased the incidence of total complications (RR = 0.30, 95% CI [0.24, 0.38], P < 0.0001). …”
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21154
Fig 3 -
Published 2024“…Different superscripts on the columns are significantly different at p≤0.05.</p>…”
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21155
Image 2_Metformin attenuates alveolar bone destruction in mice with apical periodontitis and inhibits pro-inflammatory cytokine synthesis in lipopolysaccharide-stimulated RAW264.7...
Published 2025“…</p>Results<p>Metformin significantly reduced periapical bone destruction on postoperative days 21 and 28, and decreased the number of osteoclasts on the periapical alveolar bone on postoperative day 28. …”
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21156
Table1_Identification of telomere-related lncRNAs and immunological analysis in ovarian cancer.docx
Published 2024“…PTPRD-AS1 knockdown decreased the proliferation, cloning, and migration of CAOV3 cells.…”
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21157
Image 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png
Published 2025“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”
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21158
Association of Patient Cost-Sharing with Adherence to GLP-1a and Adverse Health Outcomes
Published 2025“…Results Among 61,907 adults initiated GLP-1a, higher 30-day OOP costs were associated with decreased adherence. Patients in the highest OOP cost quartile (Q4: $80–$3,375) had significantly higher odds of non-adherence (OR: 1.25; 95% CI: 1.19–1.31) compared to those in the lowest quartile (Q1: $0–$21). …”
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21159
DataSheet1_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf
Published 2025“…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …”
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21160
Image 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.tif
Published 2025“…</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …”