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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant changes » significant challenge (Expand Search)
significant cause » significant change (Expand Search), significant gap (Expand Search), significant increase (Expand Search)
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18941
Heart looping variations in <i>Notch3</i> and <i>Nodal</i> compound mutants.
Published 2025“…(<b>F</b>) Brightfield images of wild type (f1), control <i>Notch3</i> heterozygote (f2) compared to homozygote <i>Nodal</i> mutants with decreased <i>Notch3</i> (f3) at E9.5, in a ventral view. …”
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18942
Development and validation of an ultra-performance liquid chromatography with tandem mass spectrometry method for determination of soluble repulsive guidance molecule A in human se...
Published 2024“…</p> <p>In CSF from patients with MCI and those with AD, total soluble RGMa was significantly decreasing to a median of 22.6 and 21.4 ng/ml, respectively.…”
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18943
TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts
Published 2025“…Autophagy in CAFs is constitutive and independent of STAT3, MAPK1/ERK2-MAPK3/ERK1 and phosphoinositide 3-kinase (PI3K) signaling. Despite the significant role of secretory autophagy in CAFs, its molecular machinery has remained elusive. …”
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18944
Epidural Hydromorphone for Postpartum Pain Management After Vaginal Delivery: A Randomized Clinical Trial
Published 2025“…</p><p><br></p><p dir="ltr"><b>Findings</b></p><p dir="ltr">Epidural hydromorphone demonstrated a statistically significant reduction in postpartum pain scores, a decreased requirement for supplemental analgesics, and enhanced maternal satisfaction. …”
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18945
Table 1_The impact of comorbidities on surgical outcome and mortality in minimally invasive mitral valve surgery: a systematic review.docx
Published 2025“…Left atrial (LA) diameter decreased significantly from 50.37 mm preoperatively to 40.41%mm postoperatively (p < 0.001), LVDD was significantly reduced after MIMVS (p < 0.001). …”
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18946
<i>mig-21</i> sensitizes adult DTCs to polarizing signals.
Published 2025“…A robust “extra turn” defect rate of control on <i>vab-3</i> RNAi (n=38/57) decreases with <i>mig-21(u787)</i> on <i>vab-3</i> RNAi (n=24/65), p < 0.01. …”
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18947
USUV replicates in STAT1-sufficient peripheral tissues leading to spleen and liver pathology.
Published 2025“…<b>(G)</b> H&E staining of spleen tissue collected from mock or USUV-infected mice with a 200 µm scale bar. Decreased red pulp due to massive immune cell infiltration was observed in Vav-Cre/<i>Stat1</i><sup>fl/fl</sup> and <i>Stat1</i><sup>-/-</sup> mice. …”
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18948
Excel raw data.
Published 2025“…The effectiveness of currently available antimicrobial is decreasing due to the increasing prevalence of resistant strains among bacterial isolates. …”
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18949
Table 1_Stroke-associated pneumonia with low PaO2/FiO2 ratio in acute large vessel occlusion after endovascular therapy: risk factors and prognosis.docx
Published 2025“…A deterioration in SAP manifests itself in a decreased partial pressure oxygen (PaO<sub>2</sub>)/fraction of inspired oxygen (FiO<sub>2</sub>) ratio, indicating gas exchange dysfunction. …”
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18950
Zika virus replicates efficiently in the zebrafish model and induces morphological defects.
Published 2024“…(H-I) Treatment of ZIKV-infected fish with 100 μM NITD008 decreased the viral load. Viral RNA copies (normalized to the number of larvae) are shown for each independent experiment in (H). …”
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18951
Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer”
Published 2025“…TRIM37 overexpression decreased palbociclib sensitivity, while its knockdown enhanced sensitivity and attenuated the effect of AR on RB1 levels and drug response, establishing TRIM37 as a novel E3 ligase that bound RB1 via its MATH and C-terminal domains.…”
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18952
SLMO is required for the proper function of PISD.
Published 2024“…At least 10 flies were used, and significant differences were determined using the unpaired <i>t</i> test. …”
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18953
Gene diversity of lancelet <i>Artemis.</i>
Published 2025“…<i>P</i>-values were analyzed with Student <i>t</i> tes<i>t</i>. ns, not significant.</p>…”
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18954
Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhea virus by phosphorylating the nucleocapsid protein
Published 2025“…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …”
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18955
Source data.zip
Published 2025“…In vivo, melatonin significantly increased MT1R (melatonin receptor 1A) expression in BPA-treated mouse testicular cells and the content of catalase, superoxide dismutase 2, and glutathione, while decreasing the level of malondialdehyde. …”
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18956
Image2_GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux.TIF
Published 2024“…GABA<sub>A</sub> β3 subunit knockdown causes cell cycle arrest in TNBC cell lines via decreased cyclin D1 and increased p21 expression. …”
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18957
Image1_GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux.TIF
Published 2024“…GABA<sub>A</sub> β3 subunit knockdown causes cell cycle arrest in TNBC cell lines via decreased cyclin D1 and increased p21 expression. …”
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18958
<b>Association between myristic acid in plasma triglycerides and metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes: A comprehensive analysis...
Published 2025“…After comprehensive diabetes treatment for 2 weeks, FA levels in many TGs significantly decreased; especially, FA 14:0 levels in TGs decreased notably, and this reduction was more pronounced in patients with MASLD.…”
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18959
Image 4_Transcriptome-based WGCNA reveals the molecular regulation of xylem plasticity in acclimation to drought and rewatering in mulberry.tif
Published 2024“…Most parameters were not affected significantly under moderate drought for both cultivars. …”
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18960
Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx
Published 2025“…Furthermore, OCT1 protein expression decreased after 1 h and 1 day of HH exposure (P < 0.05), while P-gp expression decreased after 1 h (P < 0.05).…”