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significant effect » significant impact (Expand Search)
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19001
Datasheet1_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen...
Published 2024“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”
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19002
Datasheet2_Efficacy and safety of Danlou tablets in the treatment of stable angina pectoris with intermingled phlegm and blood stasis syndrome in coronary heart disease: a multicen...
Published 2024“…The activated partial thromboplastin time in the treatment group decreased significantly (P < 0.05). There was no statistically significant difference in the safety indicators and incidence of adverse reactions between the two groups.…”
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19003
Altered spatial distribution of EPDCs in <i>Wt1</i><sup>Cre</sup>; <i>Sox9</i><sup>fl/fl</sup>; <i>R26</i><sup>mG</sup> hearts.
Published 2025“…Chi-square analysis indicates a significant shift in spatial distribution (p < 0.0001). …”
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19004
Table 2_Shifts in marine bird abundance and species composition following the 2014−2016 Pacific marine heatwave.docx
Published 2025“…The overall density of winter marine birds decreased and species composition significantly changed in PWS following the PMH. …”
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19005
Table 1_Shifts in marine bird abundance and species composition following the 2014−2016 Pacific marine heatwave.docx
Published 2025“…The overall density of winter marine birds decreased and species composition significantly changed in PWS following the PMH. …”
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19006
Data Sheet 1_Huoxue-Jiangtang decoction ameliorates type 2 diabetes in high-fat diet and streptozotocin-induced rats.pdf
Published 2025“…Moreover, the levels of glycogen synthetase (GS), hexokinase, superoxide dismutase (SOD), glycogen, and muscle glycogen in the HXJT group significantly increased relative to those in untreated T2DM group, while TNF-α levels decreased observably. …”
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19007
Table1_Adverse event profile differences between pralsetinib and selpercatinib: a real-world study based on the FDA adverse events reporting system.docx
Published 2024“…The risk of AEs such as decreased platelet count, anemia, decreased white blood cell count, pneumonitis, asthenia, and edema caused by pralsetinib is significantly higher than that of selpercatinib. …”
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19008
Image2_Adverse event profile differences between pralsetinib and selpercatinib: a real-world study based on the FDA adverse events reporting system.TIF
Published 2024“…The risk of AEs such as decreased platelet count, anemia, decreased white blood cell count, pneumonitis, asthenia, and edema caused by pralsetinib is significantly higher than that of selpercatinib. …”
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19009
Table2_Adverse event profile differences between pralsetinib and selpercatinib: a real-world study based on the FDA adverse events reporting system.docx
Published 2024“…The risk of AEs such as decreased platelet count, anemia, decreased white blood cell count, pneumonitis, asthenia, and edema caused by pralsetinib is significantly higher than that of selpercatinib. …”
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19010
Image1_Adverse event profile differences between pralsetinib and selpercatinib: a real-world study based on the FDA adverse events reporting system.TIF
Published 2024“…The risk of AEs such as decreased platelet count, anemia, decreased white blood cell count, pneumonitis, asthenia, and edema caused by pralsetinib is significantly higher than that of selpercatinib. …”
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19011
Supplementary Material for: Exploring the ability of novel choroidal biomarkers in predicting treatment outcomes of polypoidal choroidal vasculopathy
Published 2024“…The greater change of central macular thickness (CMT) was significantly correlated with increased CMT (P=0.030), decreased CT (P=0.042) and decreased CVI (p=0.038) at baseline. …”
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19012
Data Sheet 1_Ginsenoside Ro ameliorates cognitive impairment and neuroinflammation in APP/PS1 mice via the IBA1/GFAP-MAPK signaling pathway.docx
Published 2025“…Furthermore, the phosphorylation levels of p38 and JNK in the MAPK pathway were significantly reduced, suggesting a key mechanism for its therapeutic effects.…”
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19013
Data Sheet 1_Unlocking the adaptation mechanisms of the oleaginous microalga Scenedesmus sp. BHU1 under elevated salt stress: a physiochemical, lipidomics and transcriptomics appro...
Published 2024“…<p>Microalgae are vital for their photosynthetic abilities, contributing significantly to global oxygen production, serving as a key trophic level in aquatic ecosystems, aiding in biofuel production, assisting in wastewater treatment, and facilitating the synthesis of valuable biochemicals. …”
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19014
Data Sheet 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.xlsx
Published 2025“…</p>Results<p>Reducing the elastic moduli of heel cushioning pads led to decreased peak stresses across all directions. Notably, the peak compressive stress decreased by 52.20%–66.91%, while AP and ML shear stresses decreased by 51.05%–75.58% and 54.16%–72.42%, respectively. …”
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19015
Image 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.jpeg
Published 2025“…</p>Results<p>Reducing the elastic moduli of heel cushioning pads led to decreased peak stresses across all directions. Notably, the peak compressive stress decreased by 52.20%–66.91%, while AP and ML shear stresses decreased by 51.05%–75.58% and 54.16%–72.42%, respectively. …”
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19016
Table 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.docx
Published 2025“…</p>Results<p>Reducing the elastic moduli of heel cushioning pads led to decreased peak stresses across all directions. Notably, the peak compressive stress decreased by 52.20%–66.91%, while AP and ML shear stresses decreased by 51.05%–75.58% and 54.16%–72.42%, respectively. …”
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19017
<b><i>Escherichia coli α-hemolysin induces red blood cell retention in a microfluidic spleen-like device</i></b>
Published 2025“…</p><p dir="ltr">In the first device, which mimics the mechanical deformation of RBCs in narrow capillaries, HlyA sublytic concentrations were found to significantly impair RBC deformability. These changes were accompanied by an increase in cytosolic Ca<sup>2+</sup> and volume expansion. …”
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19018
Data Sheet 1_Bryostatin-1 enhances the proliferation and functionality of exhausted CD8+ T cells by upregulating MAP Kinase 11.docx
Published 2025“…In HIV research, it has shown anti-HIV effects during acute infection and reactivation of latent HIV in chronic infection. …”
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19019
DataSheet1_Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach.docx
Published 2024“…Further research revealed that Z-LIG/CGA treatment significantly increased IL-1R2 levels, significantly decreased IL-17RA levels, and inhibited the activation of p-STAT1, thereby alleviating cell apoptosis after MI. …”
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19020
Data Sheet 1_ClpB affects biofilm formation in methicillin-resistant Staphylococcus aureus.pdf
Published 2025“…</p>Results<p>The results showed that compared with the wild strain (WT), the biomass of ΔclpB biofilm was significantly reduced (p < 0.0001), the structure was damaged and the production of extracellular matrix (eDNA, polysaccharides, proteins) decreased. …”