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significant estimates » significant rates (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant time » significant threat (Expand Search), significant gap (Expand Search)
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19241
Table 2_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx
Published 2025“…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”
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19242
Data Sheet 1_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.zip
Published 2025“…Background and Objectives<p>Multiple sclerosis (MS) significantly impacts adolescents and young adults (aged 15–39 years), causing substantial neurological disability. …”
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19243
Table 2_MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study.docx
Published 2025“…Inflammatory markers (CRP, LPS) decreased with higher adherence (all p < 0.001). Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p < 0.001), HOMA-IR (β = −2.11; p < 0.001), CRP (β = −2.12; p < 0.001), LPS (β = −8.52; p < 0.001). …”
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19244
Data Sheet 2_Global, regional, and national trends and burden of multiple sclerosis in adolescents and young adults: a data analysis from 1990 to 2021 and projections to 2040.docx
Published 2025“…Background and Objectives<p>Multiple sclerosis (MS) significantly impacts adolescents and young adults (aged 15–39 years), causing substantial neurological disability. …”
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19245
Image 2_Apolipoprotein C1 -317H1/H2 and the rs4420638 genetic variations and risk of gestational diabetes mellitus in Chinese women: a case-control study.jpeg
Published 2025“…However, the combined H1H1/AG+GG genotype was significantly more frequent in women with GDM than in the control group. …”
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19246
Table1_Biomechanical effects of different mandibular movements and torque compensations during mandibular advancement with clear aligners: a finite element analysis.DOCX
Published 2024“…</p>Results<p>When the mandibular advancement was equal to or slightly excessed the occlusal opening distance, stress on the posterior PDL decreased and became more evenly distributed. Increasing the occlusal opening distance significantly raised stress on the posterior PDL and caused grater labial inclination of the mandibular anterior teeth. …”
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19247
Table 3_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.docx
Published 2025“…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”
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19248
Table 1_Effects of compound probiotics on growth performance, immunity, antioxidant capacity and gut microbiota in weaned rabbits.docx
Published 2025“…</p>Results and discussion<p>Our results showed that dietary supplementation with probiotic significantly promoted growth performance (e.g., increased average daily gain and decreased feed-to-gain ratio), enhanced immune function (reflected by elevated plasmic immunoglobulin levels and reduced pro-inflammatory cytokine concentrations) and improved antioxidant capacity (manifested by higher activities of superoxide dismutase and glutathione peroxidase and lower malondialdehyde content) in weaned rabbits. …”
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19249
Supplementary Material for: Camrelizumab combined with Lenvatinib and RALOX-HAIC for unresectable hepatocellular carcinoma (Cal Era): a prospective, single-arm, phase II trial
Published 2025“…Grade 3-4 treatment-related adverse events occurred in 79.5% of the subjects, with the most common being decreased neutrophil count (41%), decreased platelet count (30.8%), and increased aspartate aminotransferase (23.1%). …”
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19250
Table 1_Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021.xlsx
Published 2025“…</p>Conclusion<p>Over the past 32 years, the global burden of neonatal diseases attributable to LBW has significantly decreased, but inequality in disease burden has intensified. …”
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19251
Table_1_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xlsx
Published 2025“…We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”
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19252
Effect of session on winning model parameters for set size = 2 and set size = 4 for both male and females.
Published 2024“…Use of one-back strategy parameters changed significantly across sessions for male mice with (C) S1 “Inappropriate Lose Shift” decreasing across sessions, <i>p</i> = 0.01 (D) S2 = S4 “Stimulus Insensitive Win Stay” increasing, <i>p</i> = 0.009 and (E) S3 “Inappropriate Lose Stay” decreasing, <i>p</i> < 0.0001. …”
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19253
Image 1_Apolipoprotein C1 -317H1/H2 and the rs4420638 genetic variations and risk of gestational diabetes mellitus in Chinese women: a case-control study.jpeg
Published 2025“…However, the combined H1H1/AG+GG genotype was significantly more frequent in women with GDM than in the control group. …”
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19254
Table 2_Epidemiology of neonatal disorders attributable to low birthweight-global burden of disease research, 1990–2021.xlsx
Published 2025“…</p>Conclusion<p>Over the past 32 years, the global burden of neonatal diseases attributable to LBW has significantly decreased, but inequality in disease burden has intensified. …”
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19255
Long-Term Effects of Adalimumab in Juvenile Idiopathic Arthritis-Associated Uveitis: 3- and 6-Year Results of the ADJUVITE Trial
Published 2025“…The mean dose of methotrexate decreased significantly from 11.3 ± 4.4 mg/week at the end of the trial to 5.2 ± 6.2 mg/week at the last follow-up (<i>p</i> = 0.002). …”
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19256
Image 2_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg
Published 2025“…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”
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19257
Image2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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19258
DataSheet1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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19259
Image1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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19260
Data Sheet 1_Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism.pdf
Published 2025“…</p>Results<p>Polydatin combined with hawthorn flavonoids administration significantly reduced lipid and inflammatory cytokine levels, meanwhile, the atherosclerotic lesions in a high-fat diet-induced ApoE<sup>−/−</sup> mice were significantly decreased. …”