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20521
Table3_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx
Published 2024“…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”
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20522
Table 2_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx
Published 2025“…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…”
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20523
Supplementary Material for: MicroRNA-4497 is Downregulated in Pediatric Allergic Diseases and Suppresses Th2 Inflammation in an Animal Model
Published 2025“…Furthermore, levels of IL-4, MDC and methacholine Penh were significantly decreased in a miR-4497 treated mouse model. …”
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20524
Data Sheet 1_Desulfovibrio vulgaris exacerbates sepsis by inducing inflammation and oxidative stress in multiple organs.pdf
Published 2025“…Phosphorylation of MAPK and NF-κB pathways in peritoneal macrophages was significantly enhanced. Additionally, D. vulgaris amplified oxidative stress across multiple organs, as indicated by increased ROS levels and decreased antioxidant enzyme activity.…”
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20525
Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx
Published 2025“…In FaDu HSCC cells, siRNA-mediated HDGF knockdown significantly attenuated proliferation, migration, and invasion. …”
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20526
Table 1_Regional and age-specific global trends associated with infectious diarrhea in children under 14 years old caused by pathogenic microorganisms in 2021.docx
Published 2025“…</p>Conclusion<p>Although the global burden of diarrhea has decreased significantly, it is still high in low-income countries and low- and medium-SDI areas, and newborns are at high risk. …”
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20527
Supplementary Material for: Comparing Two Oral Immunotherapy Strategies for Sesame Allergy: Baked Goods with Sesame Paste Versus Crushed Sesame Seeds
Published 2025“…For both the baked goods and the seeds group, likelihood of severe reactions significantly decreased over time. Conclusion: A modified sesame desensitization protocol using baked sesame paste can be safely used in children with sesame allergy.…”
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20528
Table 6_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx
Published 2025“…However, the change in age-standardized rates from 1990 to 2021 declined significantly. The association between the Socio-demographic Index (SDI) and the burden of amputations in 2021 was not linear. …”
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20529
Data Sheet 1_The pan-cancer landscape of aldo-keto reductase1B10 reveals that its expression is diminished in gastric cancer.docx
Published 2024“…In tumor microenvironment, AKR1B10 was significantly correlated with immune cell infiltrations and immune gene expression. …”
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20530
Image 3_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti...
Published 2025“…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …”
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20531
Differences in lesion development of slow- and fast-growing meat-type chickens after experimental challenge with <i>Enterococcus cecorum</i>
Published 2025“…Extra-intestinal colonization with EC at 43/44 dph was significantly reduced in group ESG compared to EFG (<i>P</i> < 0.05). …”
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20532
Image 3_HIF‐1α modulates pancreatic cancer ECM proteins via the TGF‐β1/Smad signaling pathway introduction.tif
Published 2025“…Pharmacological inhibition of either HIF-1α or TGF-β1 significantly decreased the expression of ECM proteins, while TGF-β1 stimulation enhanced their production. …”
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20533
Defective autophagy in vascular smooth muscle cells promote uremic accelerated atherosclerosis
Published 2025“…<p>Individuals with chronic kidney disease (CKD) exhibit a significantly elevated risk of premature mortality, predominantly attributable to cardiovascular etiologies. …”
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20534
Natural selection diagram.
Published 2025“…Additionally, the variation in node utilization rates significantly decreased from 30.1% to 12.25%, markedly enhancing resource scheduling efficiency and overall balance within the supply chain.…”
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20535
Improved optimization results.
Published 2025“…Additionally, the variation in node utilization rates significantly decreased from 30.1% to 12.25%, markedly enhancing resource scheduling efficiency and overall balance within the supply chain.…”
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20536
Algorithm training accuracy experiments.
Published 2025“…However, after removing the integrated residual attention unit and depth-wise separable convolution, the accuracy decreased by 1.91% and the latency increased by 117ms. …”
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20537
<b>Empagliflozin reduces left ventricular mass increase and improves cardiomyocyte hypertrophy after 5/6 nephrectomy.</b>
Published 2025“…Single-nuclei RNA sequencing (snRNA-seq) and quantitative real-time polymerase chain reaction (qRT-PCR) were employed to investigate molecular mechanisms. 5/6 nephrectomy increased serum creatinine, troponin T, LVM, ejection fraction, and cardiomyocyte diameter. Empagliflozin significantly reduced LVM and cardiomyocyte hypertrophy, comparable to Telmisartan. …”
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20538
Table 2_Long-term outcomes of platinum-based chemotherapy for T4 stage sinonasal adenoid cystic carcinoma.docx
Published 2025“…Besides, chemotherapy significantly decreased 10-year OS (27.9% vs. 58.8%, P = 0.034) compared with the no-chemotherapy group. …”
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20539
Table 1_Long-term outcomes of platinum-based chemotherapy for T4 stage sinonasal adenoid cystic carcinoma.doc
Published 2025“…Besides, chemotherapy significantly decreased 10-year OS (27.9% vs. 58.8%, P = 0.034) compared with the no-chemotherapy group. …”
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20540
Gene comparison map before and after mutation.
Published 2025“…Additionally, the variation in node utilization rates significantly decreased from 30.1% to 12.25%, markedly enhancing resource scheduling efficiency and overall balance within the supply chain.…”