Average activity profiles (left column) and double-plotted actograms (right column) of <i>Marinogammarus marinus</i> (A-B) and <i>Gammarus pulex</i> (C-D) under the LD light regime... حسب Charlotte N. Underwood (5043110)

الموضوعات:

Molecular docking showed that ABT-199 can fit into active site of ALK^Mutant. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

The binding energy values of ATP, ALK inhibitors and ABT-199 to ALK were obtained from AlphaFold and modeled protein structures. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Amino acids interactions and binding energy describe that ABT-199 binds to ALK^Mutant. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Activity of female and male <i>M. marinus</i> (left column) and <i>G. pulex</i> (right column). حسب Charlotte N. Underwood (5043110)

الموضوعات:

Average activity profiles (columns 1 & 3) and double-plotted actograms (col. 2 & 4) of <i>G. pulex.</i> حسب Charlotte N. Underwood (5043110)

الموضوعات:

Western blot analysis of drug combinations. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

ALKL1196M –ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Behavioural parameters of <i>Marinogammarus marinus</i> and <i>Gammarus pulex</i> activity under varying light/dark cycles. حسب Charlotte N. Underwood (5043110)

الموضوعات:

Average activity profiles (columns 1 & 3) and double-plotted actograms (col. 2 & 4) of <i>M. marinus.</i> حسب Charlotte N. Underwood (5043110)

الموضوعات:

ALK^wt–ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

BCL2 protein keeps their expression in different conditions treatment nevertheless each EML4-ALK cell modells exhibit variable expression. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

ALK inhibitors (Positive control) and ABT199 (Proposed binding) in complex with the ALK active side. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Locomotor activity of <i>Marinogammarus marinus</i> (left column) and <i>Gammarus pulex</i> (right column). حسب Charlotte N. Underwood (5043110)

الموضوعات:

BCL2 antiapoptotic protein exhibits heterogeneous expression in Ba/F3 EML4-ALK^mutants. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Loewe synergy-antagonism score analysis shows additive and synergistic effects after ALKi and ABT-199 combination treatment. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

Light conditions for behavioural assays. Day phase length included the three-hour transitions at lights on/off, except under constant conditions (LL and DD). حسب Charlotte N. Underwood (5043110)

الموضوعات:

Negative (Prednisone) and basal (ATP) control compounds binding to ALK protein. حسب Richard Junior Zapata Dongo (17912565)

الموضوعات:

The results of linear mixed model. حسب Soheila Qanbari (20455173)

الموضوعات:

The flow of the participants from enrollment to analysis. حسب Soheila Qanbari (20455173)

الموضوعات: