Showing 1 - 20 results of 50 for search '(( significant decrease decrease ) OR ( ((significant fold) OR (significant binding)) decrease ))~', query time: 0.46s Refine Results
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6

    Probing the Histamine H<sub>1</sub> Receptor Binding Site to Explore Ligand Binding Kinetics by Sebastiaan Kuhne (1474948)

    Published 2024
    “…SKR analyses reveal that introduction of a carboxylic acid moiety can increase RT at H<sub>1</sub>R up to 11-fold. Ligand efficiency (LE) decreases upon the introduction of the negatively charged group, whereas kinetic efficiency (KE) increases up to 8.5-fold. …”
  7. 7

    Probing the Histamine H<sub>1</sub> Receptor Binding Site to Explore Ligand Binding Kinetics by Sebastiaan Kuhne (1474948)

    Published 2024
    “…SKR analyses reveal that introduction of a carboxylic acid moiety can increase RT at H<sub>1</sub>R up to 11-fold. Ligand efficiency (LE) decreases upon the introduction of the negatively charged group, whereas kinetic efficiency (KE) increases up to 8.5-fold. …”
  8. 8
  9. 9
  10. 10
  11. 11

    Multi-State Redox and Light-Driven Switching of Pseudorotaxanation and Cation Shuttling by Robert Hein (4849108)

    Published 2025
    “…Specifically, the neutral switches can be quantitatively converted between <i>anti-</i> and <i>syn-</i>folded receptor geometries by irradiation, leading to the discovery of a significant increase or decrease in cation binding affinity, which was exploited to shuttle the pseudorotaxane-forming dibenzylammonium guest between the switchable crown ethers of slightly different sizes. …”
  12. 12
  13. 13
  14. 14
  15. 15
  16. 16
  17. 17
  18. 18
  19. 19
  20. 20