Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant binding » significant burden (Expand Search), significant benefits (Expand Search)
significant fold » significant force (Expand Search), significant co (Expand Search), significant all (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant binding » significant burden (Expand Search), significant benefits (Expand Search)
significant fold » significant force (Expand Search), significant co (Expand Search), significant all (Expand Search)
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Probing the Histamine H<sub>1</sub> Receptor Binding Site to Explore Ligand Binding Kinetics
Published 2024“…SKR analyses reveal that introduction of a carboxylic acid moiety can increase RT at H<sub>1</sub>R up to 11-fold. Ligand efficiency (LE) decreases upon the introduction of the negatively charged group, whereas kinetic efficiency (KE) increases up to 8.5-fold. …”
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Probing the Histamine H<sub>1</sub> Receptor Binding Site to Explore Ligand Binding Kinetics
Published 2024“…SKR analyses reveal that introduction of a carboxylic acid moiety can increase RT at H<sub>1</sub>R up to 11-fold. Ligand efficiency (LE) decreases upon the introduction of the negatively charged group, whereas kinetic efficiency (KE) increases up to 8.5-fold. …”
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Multi-State Redox and Light-Driven Switching of Pseudorotaxanation and Cation Shuttling
Published 2025“…Specifically, the neutral switches can be quantitatively converted between <i>anti-</i> and <i>syn-</i>folded receptor geometries by irradiation, leading to the discovery of a significant increase or decrease in cation binding affinity, which was exploited to shuttle the pseudorotaxane-forming dibenzylammonium guest between the switchable crown ethers of slightly different sizes. …”
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