يعرض 1,101 - 1,120 نتائج من 1,245 نتيجة بحث عن '(( significant decrease decrease ) OR ( ((significant genes) OR (significant changes)) decrease ))~', وقت الاستعلام: 0.41s تنقيح النتائج
  1. 1101

    Image 2_Evaluating two live-attenuated vaccines against Salmonella enterica serovar Reading in turkeys: reduced tissue colonization and cecal tonsil transcriptome responses.pdf حسب Melissa S. Monson (8281047)

    منشور في 2024
    "…Salmonella dissemination to the spleen was significantly reduced by both vaccines. Gene expression of intestinal transporters (such as SCNN1B and SLC10A2) and tight junction proteins was significantly decreased in the turkey cecal tonsil transcriptome at 2 DPI with S. …"
  2. 1102

    Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx حسب Chen-xiao Liu (22750118)

    منشور في 2025
    "…TCF3 knockdown significantly attenuated these EMT changes and increased autophagy markers, as evidenced by decreased P62 levels (p < 0.01) and increased LC3-II/I ratio (p < 0.001) and Beclin-1 expression (p < 0.01). …"
  3. 1103

    KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity حسب Mengyu Liu (2890397)

    منشور في 2024
    "…Further analysis indicated significant impairment of autophagic flux by TMT via suppressed lysosomal function, such as by inhibiting lysosomal proteolysis and changing the lysosomal pH, thereby contributing to defects in autophagic clearance and subsequently leading to nerve cell death. …"
  4. 1104

    The alien A<i>cacia salicina</i> invasive does not infiltrate the native soil rhizobial symbiosis networks حسب Mokhtar Rejili (17631037)

    منشور في 2024
    "…Network topology remained consistent over the invasion gradient, whereas native legume-associated rhizobia underwent significant change as acacias took over more the landscape. …"
  5. 1105

    Image 2_Standardized aqueous extract of Abutilon theophrasti Medic. ameliorates oxidative stress and inflammatory responses against hydrochloric acid/ethanol-induced gastric ulcer... حسب Hui Guo (110581)

    منشور في 2025
    "…GSE233973 and GSE264263 datasets with Helicobacter pylori (HP)-infected and normal human biospecimens from the Gene Expression Omnibus (GEO) database were normalized and subjected to identification of differentially expressed genes (DEGs). …"
  6. 1106

    Image 1_Standardized aqueous extract of Abutilon theophrasti Medic. ameliorates oxidative stress and inflammatory responses against hydrochloric acid/ethanol-induced gastric ulcer... حسب Hui Guo (110581)

    منشور في 2025
    "…GSE233973 and GSE264263 datasets with Helicobacter pylori (HP)-infected and normal human biospecimens from the Gene Expression Omnibus (GEO) database were normalized and subjected to identification of differentially expressed genes (DEGs). …"
  7. 1107

    Supplementary file 3_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg حسب Yuhui Zhang (399617)

    منشور في 2025
    "…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
  8. 1108

    Supplementary file 4_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx حسب Yuhui Zhang (399617)

    منشور في 2025
    "…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
  9. 1109

    Table_2_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.docx حسب Živa Frangež (5946392)

    منشور في 2025
    "…This reduction correlated with changes in the expression of autophagic activity markers, suggesting decreased basal levels of autophagy in primary and metastatic melanomas. …"
  10. 1110

    Supplementary file 1_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg حسب Yuhui Zhang (399617)

    منشور في 2025
    "…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
  11. 1111

    Image_2_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.jpg حسب Živa Frangež (5946392)

    منشور في 2025
    "…This reduction correlated with changes in the expression of autophagic activity markers, suggesting decreased basal levels of autophagy in primary and metastatic melanomas. …"
  12. 1112

    Table_1_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.docx حسب Živa Frangež (5946392)

    منشور في 2025
    "…This reduction correlated with changes in the expression of autophagic activity markers, suggesting decreased basal levels of autophagy in primary and metastatic melanomas. …"
  13. 1113

    Supplementary file 6_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx حسب Yuhui Zhang (399617)

    منشور في 2025
    "…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
  14. 1114

    Supplementary file 2_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg حسب Yuhui Zhang (399617)

    منشور في 2025
    "…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
  15. 1115

    Image_1_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.jpg حسب Živa Frangež (5946392)

    منشور في 2025
    "…This reduction correlated with changes in the expression of autophagic activity markers, suggesting decreased basal levels of autophagy in primary and metastatic melanomas. …"
  16. 1116

    Supplementary file 5_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx حسب Yuhui Zhang (399617)

    منشور في 2025
    "…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
  17. 1117

    Table 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.xlsx حسب Huijing Tang (19133347)

    منشور في 2025
    "…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …"
  18. 1118

    Supplementary file 1_Weissella confusa alleviates experimental colitis in mice by regulating inflammatory pathways and gut microbiota.docx حسب Huijing Tang (19133347)

    منشور في 2025
    "…</p>Results<p>Compared with DSS group, W. confusa Wc1982 significantly improved the disease phenotypes of colitis mice including decreased DAI and pathological score and reduced colon shortening, decreased colonic IL-17, IL-6, and TNF-α levels and serum lipopolysaccharide (p < 0.05), and downregulated the expression of key genes of IL-17 pathway (Lcn2, Mmp3, Mmp13, Ptgs2; p < 0.05). …"
  19. 1119

    Image 1_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.tiff حسب Yulia Dwi Setia (21590591)

    منشور في 2025
    "…Maximal parasite accumulation in the proximal colon was observed at 8 dpi in histological examination as well as qPCR. Colon length was significantly shortened at 3 dpi. Goblet cell area significantly reduced at 8 dpi (p < 0.05). …"
  20. 1120

    Table 2_Down-regulation of colon mucin production induced by Eimeria pragensis infection in mice.xlsx حسب Yulia Dwi Setia (21590591)

    منشور في 2025
    "…Maximal parasite accumulation in the proximal colon was observed at 8 dpi in histological examination as well as qPCR. Colon length was significantly shortened at 3 dpi. Goblet cell area significantly reduced at 8 dpi (p < 0.05). …"