Discovery of Dual-Acting Biofilm Inhibitors against Pseudomonas aeruginosa by the Coupling of 3‑Hydroxypyridin-4(1<i>H</i>)‑ones with <i>N</i>‑Phenylamide QS Inhibitors by Hao-Zhong Long (19685972)

“…The hit compound <b>19l</b> (IC₅₀ = 0.33 ± 0.06 μM) demonstrated significant biofilm inhibition compared to previously reported 3-hydroxypyridin-4(1<i>H</i>)-one derivatives <i>in vitro</i>. …”

Delta <i>CC</i> heatmap. by Curtis Chepsiror (21368103)

PfIleRS-SANC456 delta <i>CC.</i> by Curtis Chepsiror (21368103)

Data Sheet 1_Integrated computational and experimental identification of N-[(1H-1,2,4-triazol-3-yl)phenyl]-1-(1H-pyrazolo[3,4-b]pyridin-3-yl)methanamide as a potent and selective T... by Xinxin Ying (21507500)

“…Survival analysis revealed a significant correlation between elevated TIM-3 expression and decreased patient survival. …”

Fig 9 - BC. by Curtis Chepsiror (21368103)

AMP binding free energy calculations and per-residue decomposition of holo and PfIleRS-SANC systems. by Curtis Chepsiror (21368103)

Fig 10 - EC. by Curtis Chepsiror (21368103)

Amino acid metabolic pathways are influenced by the NC1 POM cycle over expression. by Bonnie A. McNeil (22331601)

“…The size of each circle reflects the number of “hits” relevant to the pathway with red having higher and yellow having lower significance based on <i><i>p</i></i>-value score.…”

Targeting of Vps34 reduces B16F10 tumor growth and working model for Vps34-dependent regulation of eTreg transitional heterogeneity and maintenance. by Erienne G. Norton (9612079)

Alternative representation of daunorubicin fluorescence testing of novel inhibitors. by Lauren A. McCormick (20540638)

PERCOM, an unbiased and easily-accessible protein-centric analysis workflow. by Brian Foo (19273132)

Graphical overview of study. by Brian Foo (19273132)

supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma by Takuto Itano (16830105)

“…Statistical significance: *p < 0.05; **p < 0.01. Immunoblot analysis of lysates from AD-RD cells treated with 1 nM actinomycin D and 1 µM osimertinib. …”

Table 1_Ribosomes binding to TAS transcripts buffer ta-siRNA biogenesis in Arabidopsis thaliana.docx by Han Wang (254423)

“…Conversely, the deletion of ribosome-binding regions led to a significant reduction in ta-siRNA abundance without affecting mRNA levels in the one-hit model. …”

Table 1_Advances in sulodexide-based long-term anticoagulation for a myasthenia gravis patient with giant thymoma.docx by Zhou Liu (1506679)

Table 1_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx by Qiqi Wu (4895728)

Data Sheet 1_Andrographolide suppresses chondrosarcoma cell migration and invasion by inhibiting the PI3K/Akt/mTOR signaling pathway and activating autophagy.pdf by Chun-Fei Wu (22315444)

“…WB results also revealed that Andro (5, 20, and 50 μM) reduced p62 expression, while Beclin-1 expression and the LC3A/B-II/LC3A/B-I ratio increased in SW1353 and Hs 819.T cells. …”

Supplementary Material for: Placebo effect of verbal instructions coupled with pharmacological treatment: results from a randomized controlled trial in migraine patients by figshare admin karger (2628495)

“…Kellner’s scale of change was administered at T1-T5. Results: Patients who received strongly positive instructions had no HIT decrease (p = 0.177; η2 = 0.034). …”

TgHCF101 is involved in Fe-S cluster biogenesis of the CIA pathway. by Eléa A. Renaud (18192764)

“…<p><b>(A)</b> Volcano plot showing differential expression of proteins impacted by TgHCF101 depletion after 72 h of ATc treatment analyzed by label-free quantitative proteomic. Cut-offs were set at ≤1.5- or ≥1.5-fold change (FC) and <i>p</i>-value ≤0.05. …”

Table 2_Ribosomes binding to TAS transcripts buffer ta-siRNA biogenesis in Arabidopsis thaliana.xlsx by Han Wang (254423)

“…Conversely, the deletion of ribosome-binding regions led to a significant reduction in ta-siRNA abundance without affecting mRNA levels in the one-hit model. …”