Design, synthesis and biological evaluation of non-glucosidal based 1,3,4-thiadiazoles as SGLT-2 inhibitors by Shivani Sharma (255210)

“…SSS 6 and SSS 2 significantly decreased blood glucose levels (137 ± 4.89 mg/dL and 183 ± 15.07 mg/dL) relative to dapagliflozin (158 ± 15.9 mg/dL).…”

Data Sheet 1_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.pdf by Arjanneke F. van de Merbel (5809940)

“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”

Data Sheet 2_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.docx by Arjanneke F. van de Merbel (5809940)

“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”

DataSheet1_Changes in serum uteroglobin level in type 2 diabetes mellitus patients.docx by Joung Youl Lim (18237598)

“…Uteroglobin levels were not significantly correlated with other metabolic parameters, except BMI, HOMA-β and eGFR. …”

Figure 4 from Claudin-4 Modulates Autophagy via SLC1A5/LAT1 as a Mechanism to Regulate Micronuclei by Fabian R. Villagomez (18098633)

“…<p>Correlation of amino acids transport with the clinical significance of claudin-4 in ovarian cancer. Reported proteins interacting with claudin-4 in HGSOC cells were employed to construct PPN, aiming to identify key elements and cellular functions associated with the clinical significance of claudin-4 in HGSOC tumors. …”

Image 1_Enrichment of prevotella melaninogenica in the lower respiratory tract links to checkpoint inhibitor pneumonitis and radiation pneumonitis.jpg by Jiajun Chen (1279269)

“…Compared to the LC-P group, the CIP/RP group had significantly high levels of Prevotella melaninogenica species and lymphocyte percentage in BALF but significantly low levels of lymphocytes, eosinophils and albumin in peripheral blood. …”

Data Sheet 1_Enrichment of prevotella melaninogenica in the lower respiratory tract links to checkpoint inhibitor pneumonitis and radiation pneumonitis.zip by Jiajun Chen (1279269)

“…Compared to the LC-P group, the CIP/RP group had significantly high levels of Prevotella melaninogenica species and lymphocyte percentage in BALF but significantly low levels of lymphocytes, eosinophils and albumin in peripheral blood. …”

Table 1_Changes in rat plasma proteomes during the first week after birth.docx by Lilong Wei (426321)

“…The plasma of first-week rats, compared to that in newborn rats using label-free quantification, showed that the levels of 42 proteins significantly increased while those of 17 proteins decreased. …”

Table 2_Changes in rat plasma proteomes during the first week after birth.xlsx by Lilong Wei (426321)

“…The plasma of first-week rats, compared to that in newborn rats using label-free quantification, showed that the levels of 42 proteins significantly increased while those of 17 proteins decreased. …”

Data Sheet 1_Longitudinal relationships between serum ferritin and prognosis among severe community-acquired pneumonia patients.doc by Jing Xu (15337)

“…</p>Results<p>The serum ferritin level was significantly increased in severe CAP patients upon initial hospitalization compared to healthy participants, and it decreased after therapy. …”

Raw Data. by Hongfei Liu (1396348)

“…COS supplementation significantly increased serum superoxide dismutase activity and jejunal mucosal glutathione peroxidase activity, and significantly decreased serum malondialdehyde level (<i><i>P</i></i> < 0.05). …”

Table 3_Pediococcus pentosaceus JS35 improved flavor, metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacity.xlsx by Caiyan Meng (20821640)

“…Furthermore, the fermented supernatant supplementation significantly prolonged the lifespan of Caenorhabditis elegans. …”

Table 2_Pediococcus pentosaceus JS35 improved flavor, metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacity.xlsx by Caiyan Meng (20821640)

“…Furthermore, the fermented supernatant supplementation significantly prolonged the lifespan of Caenorhabditis elegans. …”

Table 1_Pediococcus pentosaceus JS35 improved flavor, metabolic profile of fermentation supernatant of mulberry leaf powder and increased its antioxidant capacity.docx by Caiyan Meng (20821640)

“…Furthermore, the fermented supernatant supplementation significantly prolonged the lifespan of Caenorhabditis elegans. …”

Supplementary file 1_Analysis of microbial composition in different dry skin areas of Beijing women.docx by Jingtao Wang (828021)

“…At the genus level, the relative abundance of Streptococcus was significantly increased in the dry skin group, whereas a decreasing trend was observed for Cutibacterium. …”

Data Sheet 1_Clinical comparison of radiofrequency ablation and surgical resection in treating pulmonar metastasis of hepatoblastoma.docx by Yang Li (7082)

“…</p>Results<p>The average levels of AFP in both the radiofrequency ablation group and the surgical resection group decreased significantly after treatment, with no statistical significance between the groups (P>0.05). …”

Table 1_To elucidate the effect of Ruanjian Qingmai granules on arteriosclerosis obliterans from the perspective of cholesterol efflux.docx by Chenglin Jia (578595)

“…</p>Results<p>Ruanjian Qingmai granules significantly decreased lipid deposition and significantly increased the expression of CYP7A1 mRNA in both zebrafish and HepaRG cells. …”

Data Sheet 1_Wilt disease reshapes rhizosphere microbiota in small yellow ginger soils.docx by Qing Sun (492552)

“…</p>Results<p>Ginger wilt disease significantly altered the rhizosphere soil bacterial community structure and composition: the relative abundance of Proteobacteria increased significantly, primarily due to the enrichment of the genus Ralstonia; conversely, the relative abundance of Acidobacteriota, Firmicutes, and Chloroflexi significantly decreased. …”

Systematic All-Hydrocarbon Stapling Analysis for Cecropin A Generates a Potent and Stable Antimicrobial Peptide by Yejiao Shi (6391688)

“…By evaluating antimicrobial and hemolytic activities, CEC-2–9 with the <i>C</i>-terminus threonine and lysine being stapled was identified as the optimal one. It exerted significantly enhanced antibacterial potency with more severe bacterial membrane damage capacity. …”

The effect of HA digestion and HA replenishment alone or with CS on barrier function measured by TEER. by Charlotte J. van Ginkel (20790466)

“…(B) Hyaluronidase treatment (n = 8) gradually increased TEER, this significantly differed from the untreated group (n = 8) and the PS treated group (n = 8) (p < 0,001). …”