يعرض 19,321 - 19,340 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( ((significant level) OR (significant effect)) decrease ))', وقت الاستعلام: 0.69s تنقيح النتائج
  1. 19321

    Supplementary data.xlsx حسب Danjun Li (21443051)

    منشور في 2025
    "…Here, we report for the first time that NAD+ levels are significantly lower in blastocysts cultured in vitro than that in blastocysts developed in vivo, leading to impaired Sirt6 function, further triggering telomere shortening of the inner cell mass and possibly affecting newborn offspring. …"
  2. 19322

    Table 1_Early identification of sarcopenia in patients with diabetes mellitus combined with osteoporosis: development and validation of a gender-specific nomogram.docx حسب Mingzhong Yu (21215879)

    منشور في 2025
    "…</p>Results<p>The prevalence of sarcopenia in patients with T2DM combined with osteoporosis was 33.88%, with men having a significantly higher prevalence than women. Among male patients, body mass index, 25-hydroxyvitamin D, and calcium levels were associated with a decreased risk of sarcopenia, whereas age and weight-adjusted waist index were associated with an increased risk. …"
  3. 19323

    Data Sheet 1_HAX1, gene responsible for Kostmann syndrome, regulates gingival epithelial barrier function via intracellular trafficking of JAM1.pdf حسب Keita Tanigaki (13162449)

    منشور في 2025
    "…In HAX1-knockdown IHGE cells, significantly decreased levels of JAM1 were found. Additionally, cisplatin, a chemotherapeutic agent reported to inhibit HAX1, also led to decreased expression of both HAX1 and JAM1. …"
  4. 19324

    Table 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.docx حسب Leqing Zhou (20981021)

    منشور في 2025
    "…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…"
  5. 19325

    DataSheet_1_FCGR2/3 polymorphisms are associated with susceptibility to Kawasaki disease but do not predict intravenous immunoglobulin resistance and coronary artery aneurysms.docx حسب Paula Uittenbogaard (19691794)

    منشور في 2024
    "…Treatment with intravenous immunoglobulin (IVIg) significantly decreases the risk of CAA, possibly through competitive binding to Fc-gamma receptors (FcγRs), which reduces the binding of pathological immune complexes. …"
  6. 19326

    Image 3_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif حسب Leqing Zhou (20981021)

    منشور في 2025
    "…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…"
  7. 19327

    Table 1_Targeting nail psoriasis: IL-17A inhibitors demonstrate site-specific superiority over IL-23 inhibitor in a 24-week dermoscopy-guided real-world cohort.docx حسب Xiamei Yan (21014921)

    منشور في 2025
    "…</p>Results<p>(1) By week 24, PASI, BSA, DLQI and NAPSI scores had significantly decreased from baseline in all groups (P<0.001). (2) By week 24: SEC, IXE, and GUS groups saw nail matrix NAPSI score improvements of 65.9%, 60.5%, and 51.5%, with 68%, 55%, and 30% achieving NAPSI 60; Nail bed NAPSI score improvements were 58.8%, 68.6%, and 65.8%, with 28%, 65%, and 40% achieving NAPSI 60; Total NAPSI score improvements were 62.7%, 64.6%, and 53.7%, with 44%, 70%, and 30% achieving NAPSI 60. (3) All patients in the SEC and IXE groups achieved PASI 75, compared to 85% in the GUS group. …"
  8. 19328

    Table1_Adverse event signal mining and severe adverse event influencing factor analysis of Lumateperone based on FAERS database.docx حسب Yanjing Zhang (401134)

    منشور في 2024
    "…Conversely, concomitant use of CYP3A4 inhibitors or drugs metabolized by CYP3A4 was associated with a decreased risk of severe AEs (OR = 0.524 [0.434, 0.633], P = 0.000).…"
  9. 19329

    Table 1_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.docx حسب Leqing Zhou (20981021)

    منشور في 2025
    "…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…"
  10. 19330

    Table 1_Evaluating the Implementation of fan-beam CT-guided online adaptive re-planning in definitive cervical cancer radiotherapy.docx حسب Shuai Sun (775057)

    منشور في 2025
    "…This approach has shown significant improvements in dose distribution and the potential to provide clinical benefits by reducing acute toxicity.…"
  11. 19331

    Image 1_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif حسب Leqing Zhou (20981021)

    منشور في 2025
    "…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…"
  12. 19332

    Data Sheet 1_The impact of immune checkpoint inhibitors on prognosis in unresectable hepatocellular carcinoma treated with TACE and lenvatinib: a meta-analysis.zip حسب Wei Zhang (405)

    منشور في 2025
    "…The TACE+L+I group had a significantly higher incidence of hypothyroidism compared to the TACE+L group (RR = 1.81, 95%CI:1.20, 2.71, p<0.05), but there was no significant difference in other adverse events, such as hypertension, diarrhea, hand-foot syndrome, fatigue, elevated AST, elevated ALT, decreased appetite, hypothyroidism, abdominal pain, thrombocytopenia, rash, and nausea.…"
  13. 19333

    Data sources and descriptions. حسب Zeduo Zou (21672789)

    منشور في 2025
    "…As the results show, during the study period: (1) Temporal Trends: annual PM2.5 concentrations exhibited significant declines, with BTH decreasing from 1004.71 μg/m<sup>3</sup> (2006) to 528 μg/m<sup>3</sup> (2020), YRD from 1434.81 μg/m<sup>3</sup> (2008) to 621 μg/m<sup>3</sup>, and PRD from 405.02 μg/m<sup>3</sup> (2007) to 292 μg/m<sup>3</sup>. …"
  14. 19334

    Replication package for "Measuring trade costs and analyzing the determinants of trade growth between Cambodia and major trading partners: 1993-2019" حسب Borin Keo (20919743)

    منشور في 2025
    "…Despite their practical significance and increasing policy attention in the country, little is known about these costs.…"
  15. 19335

    Image 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif حسب Leqing Zhou (20981021)

    منشور في 2025
    "…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…"
  16. 19336

    Supplementary Material for: Head positioning for stroke blood flow augmentation assisting reperfusion therapies (HEAD-START) study حسب figshare admin karger (2628495)

    منشور في 2025
    "…Trendelenburg positioning was maintained for 24h if lesion volume significantly decreased (≥5mL) and stroke reperfusion was suboptimal or undetermined. …"
  17. 19337

    Table 1_Gypenoside XLIX inhibiting PI3K/AKT/FOXO1 signaling pathway mediated neuronal mitochondrial autophagy to improve patients with ischemic stroke.docx حسب Yonglei Liu (5485793)

    منشور في 2025
    "…</p>Results<p>Gypenoside XLIX significantly improved neuronal viability (p < 0.01), reduced apoptosis (p < 0.01), and decreased ROS levels (p < 0.001) in OGD cells. …"
  18. 19338

    Data Sheet 1_Dietary supplementation with polypeptin and bioture improves growth, feed utilization, antioxidant capacity, and disease resistance in juvenile hybrid grouper (Epineph... حسب Futao Jing (22516817)

    منشور في 2025
    "…The results showed that co-supplementation significantly improved multiple performance indicators, exhibiting notable synergistic effects: final body weight, weight gain, and specific growth rate increased, while feed conversion ratio and hepatosomatic index decreased. …"
  19. 19339

    Table 1_Platelet-rich plasma improves pain and function in knee osteoarthritis: a retrospective study.docx حسب Yi-Ting Sun (4691629)

    منشور في 2025
    "…</p>Results<p>At 6 months, the median (IQR) VAS score significantly decreased from 66.5 (27) to 24 (34) (95% CI = −38 to −30.5), p < 0.001), and WOMAC scores improved from 29 (22) to 12 (14) (95% CI = −16.5 to −12), p < 0.001). …"
  20. 19340

    Data Sheet 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.zip حسب Na Wang (193263)

    منشور في 2025
    "…Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …"