بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significant linear » significant clinical (توسيع البحث), significant gender (توسيع البحث), significant long (توسيع البحث)
significant level » significance level (توسيع البحث), significance levels (توسيع البحث), significant gender (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significant linear » significant clinical (توسيع البحث), significant gender (توسيع البحث), significant long (توسيع البحث)
significant level » significance level (توسيع البحث), significance levels (توسيع البحث), significant gender (توسيع البحث)
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19041
Table_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.XLSX
منشور في 2025"…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"
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19042
Table 1_Nitrogen and phosphorus fertilizer use efficiency improves alfalfa (Medicago sativa L.) production and performance in alkaline desert soil.docx
منشور في 2025"…Optimizing the combination of nitrogen and phosphorus fertilizers can maximally significantly enhance farmers’ economic returns while concurrently mitigate soil environmental pollution. …"
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19043
Table 2_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx
منشور في 2024"…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…"
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19044
Data Sheet 1_A comprehensive examination and analysis of the effectiveness and safety of finerenone for the treatment of diabetic kidney disease: a systematic review and meta-analy...
منشور في 2024"…</p>Results<p>The analysis of 4 randomized controlled trials involving 13,943 participants found that finerenone treatment significantly decreased the urine albumin-to-creatinine ratio compared to placebo. …"
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19045
Fasting inhibits glycolysis and migration/invasion in gallbladder cancer via PCBP2/ANGPTL4 signaling
منشور في 2025"…We found that fasting could inhibit glycolysis and cell migration/invasion in GBC cells and that fasting mimic diets could significantly inhibit GBC cell proliferation in a mouse xenograft model. …"
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19046
Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx
منشور في 2025"…Western blotting demonstrated that HDGF knockdown suppressed AKT/mTOR signaling, as indicated by reduced p-AKT and p-mTOR levels, and decreased VEGFA expression.</p>Conclusion<p>Our findings establish HDGF as a key promoter of HSCC progression through dual regulation of EMT and AKT/mTOR/VEGF pathways, suggesting its potential as a therapeutic target. …"
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19047
Image 1_Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.tif
منشور في 2025"…Moreover, the overexpression of FOXJ1 (one of the DEGs) significantly decreased the proliferation, invasion, migration and Epithelial-Mesenchymal Transition (EMT) process in cervical cancer cells. …"
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19048
Presentation_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.pdf
منشور في 2025"…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"
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19049
Data Sheet 1_Herbal essential oils improve growth, antioxidant response, and gene expression in Nile Tilapia fingerlings.pdf
منشور في 2025"…Hematological parameters increased, while serum cholesterol and triglyceride levels decreased. Enhanced lysozyme activity, phagocytic rate, IgM concentration, and antioxidant enzymes (SOD and CAT) were observed in the 30 and 60 mL/kg groups. …"
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19050
Image 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.pdf
منشور في 2025"…</p>Results<p>New functional morbidity occurred in 38 children (32%) and was associated with increased plasma levels of interleukin (IL)-6, IL-18, sIL-2Ra, MCP1, IL-8 (CXCL8), sIL-1RII, IL-10, MIP1a, and IL-2r and decreased RANTES (CCL5) (p < .001) at all three timepoints. …"
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19051
Experiment 3 –trial E.
منشور في 2024"…Violin plots show Cq median (solid line). Statistical significance levels were calculated with the GraphPad Prism v9.3.1 (* = p ≤ 0.05; n = 3).…"
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19052
Image 3_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif
منشور في 2025"…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …"
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19053
Image 2_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif
منشور في 2025"…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …"
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19054
Data Sheet 1_Pinostilbene inhibits lung epithelial-mesenchymal transition and delays pulmonary fibrosis by modulating the PI3K/Akt pathway.docx
منشور في 2025"…Mechanistic studies identified the PI3K/Akt pathway as a target of PIN, with Western blot analysis showing decreased phosphorylation levels of PI3K and Akt. These findings suggest that PIN inhibits pulmonary EMT and delays the progression of pulmonary fibrosis by modulating the PI3K/Akt pathway, providing a promising therapeutic avenue for lung diseases associated with EMT.…"
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19055
Image 1_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif
منشور في 2025"…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …"
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19056
Supplementary file 3_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.docx
منشور في 2025"…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …"
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19057
Supplementary file 2_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.zip
منشور في 2025"…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …"
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19058
Supplementary file 1_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.zip
منشور في 2025"…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …"
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19059
Genetic prediction of the relationship between mitochondrial proteins and diabetic polyneuropathy risk: a Mendelian randomization study
منشور في 2025"…</p> <p>Elevated COA3 levels (OR = 0.5774, 95% CI: 0.4466–0.7465, <i>p</i> < 0.01) decreased DPN risk, while elevated NFU1 (OR: 1.3992, 95% CI: 1.0935–1.7904, <i>p</i> = 0.0075) and SARS2 (OR: 1.3660, 95% CI: 1.0651–1.7520, <i>p</i> = 0.0140) increased risk.…"
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19060
The evolution of inharmonicity and noisiness in contemporary popular music
منشور في 2025"…From 1961 to 1972, inharmonicity in popular music, initially only slightly higher than in orchestral music, increased significantly. Between 1972 and 1986, this rise in inharmonicity was accompanied by an increase in noise, but since 1986, both inharmonicity and noise have moderately decreased. …"