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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant amount » significant impact (Expand Search)
significant main » significant gap (Expand Search), significant cause (Expand Search), significant mediating (Expand Search)
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18701
The effects of CHRM2 knockdown on osteogenic differentiation and cell proliferation.
Published 2025“…(B) The RT-qPCR results showed that the expression of CHRM2 in cells with Si-CHRM2 knockdown decreased significantly. (C) The cell proliferation were measured by OD value at 450 nm, and the observation time points were at 0, 24, 48, 72 and 96 hours. …”
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18702
Table 1_Influence of age and sex on the diagnostic accuracy of pleural fluid carcinoembryonic antigen for malignant pleural effusion: a post hoc analysis.docx
Published 2025“…Subgroup analyses with both cohorts revealed the decreased AUC in older patients. The resampling method revealed decreased AUC with the advancement of age.…”
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18703
Image 4_Transcriptome-based WGCNA reveals the molecular regulation of xylem plasticity in acclimation to drought and rewatering in mulberry.tif
Published 2024“…Most parameters were not affected significantly under moderate drought for both cultivars. …”
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18704
Data Sheet 1_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.zip
Published 2025“…SQOR knockdown resulted in decreased cell viability, decreased migration ability and increased MDA level under hypoxic Ersatin induced conditions. …”
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18705
Table 6_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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18706
Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx
Published 2025“…Furthermore, OCT1 protein expression decreased after 1 h and 1 day of HH exposure (P < 0.05), while P-gp expression decreased after 1 h (P < 0.05).…”
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18707
Data Sheet 2_Menthone lowers H3K27ac levels to inhibit Fusarium proliferatum growth.xlsx
Published 2025“…</p>Results<p>This study demonstrated that menthone, the primary component of Mentha haplocalyx EO, exhibited notable antifungal activity against Fusarium proliferatum (EC50 = 6.099 mmol/L). The treatment significantly inhibited hyphal growth, reduced spore germination rates from 31.49 to 4.95%, decreased spore viability from 46.88 to 20.91%, and reduced spore production by a factor of 17.92 compared with the control group while simultaneously enhancing cell membrane permeability. …”
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18708
Data Sheet 1_The dynamics of lowland river sections of Danube and Tisza in the Carpathian basin.pdf
Published 2025“…Almost all the water level and discharge records indicate a decadal decreasing trend for annual maximum values. The timing (day of the year) for annual maxima and minima is evaluated. …”
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18709
Presentation 1_Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering.pptx
Published 2025“…Background<p>The advent of biologics has significantly transformed treatment strategies for neuromyelitis optica spectrum disorder (NMOSD). …”
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18710
Supplementary Material for: Pre- and post-operative Exercise and Nutrition Therapy in Patients with Esophageal Cancer Undergoing Esophagectomy: A Prospective Interventional Study
Published 2025“…The SMM increased by 4.9% for T1–T2 (p < 0.001) but decreased by 10.1% for T1–T3 (p < 0.001), suggesting that the primary outcome was not achieved. …”
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18711
Table1_Maslinic acid induces autophagy and ferroptosis via transcriptomic and metabolomic reprogramming in prostate cancer cells.xlsx
Published 2024“…Herein we found that MA inhibits prostate cancer cell proliferation by decreasing CDK2, CDK4, and CDK6 expression and concurrently increasing p27, Rb, p-Rb expression. …”
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18712
Table3_Maslinic acid induces autophagy and ferroptosis via transcriptomic and metabolomic reprogramming in prostate cancer cells.xlsx
Published 2024“…Herein we found that MA inhibits prostate cancer cell proliferation by decreasing CDK2, CDK4, and CDK6 expression and concurrently increasing p27, Rb, p-Rb expression. …”
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18713
Data Sheet 1_Shengxian decoction alleviates cyclophosphamide-induced immunosuppression via improving B cell-mediated immune responses.docx
Published 2025“…</p>Results<p>SXD treatment ameliorates decreased splenic and thymic organ indexes, as well as decreased lymphocyte number in the spleen in immunosuppressed mice. …”
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18714
Image 3_Transcriptome-based WGCNA reveals the molecular regulation of xylem plasticity in acclimation to drought and rewatering in mulberry.tif
Published 2024“…Most parameters were not affected significantly under moderate drought for both cultivars. …”
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18715
Image 1_Transcriptome-based WGCNA reveals the molecular regulation of xylem plasticity in acclimation to drought and rewatering in mulberry.tif
Published 2024“…Most parameters were not affected significantly under moderate drought for both cultivars. …”
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18716
Table 3_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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18717
Table 5_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
Published 2025“…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…”
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18718
Prevalence of Vision Loss in North Africa and Middle East in 2020: Magnitude and Temporal Trends
Published 2025“…</p> <p>Although the absolute numbers of people with blindness and MSVI have increased between 1990 and 2020 in NAME region, the overall prevalence and the age standardized prevalence in those aged 50+ years have decreased significantly for the same period.</p>…”
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18719
Data Sheet 1_Growth regulation mechanism of Rhododendron moulmainense to high-temperature stress: integrated physiological, transcriptomic, and metabolomic insights.docx
Published 2025“…The findings demonstrated that high-temperature stress decreased chlorophyll fluorescence and contents, which was validated by the damaged chloroplast structure in transmission electron microscopy. …”
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18720
Image 1_Growth regulation mechanism of Rhododendron moulmainense to high-temperature stress: integrated physiological, transcriptomic, and metabolomic insights.jpg
Published 2025“…The findings demonstrated that high-temperature stress decreased chlorophyll fluorescence and contents, which was validated by the damaged chloroplast structure in transmission electron microscopy. …”