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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant changes » significant challenge (Expand Search)
significant main » significant gap (Expand Search), significant amount (Expand Search), significant cause (Expand Search)
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18741
DataSheet_1_FCGR2/3 polymorphisms are associated with susceptibility to Kawasaki disease but do not predict intravenous immunoglobulin resistance and coronary artery aneurysms.docx
Published 2024“…Treatment with intravenous immunoglobulin (IVIg) significantly decreases the risk of CAA, possibly through competitive binding to Fc-gamma receptors (FcγRs), which reduces the binding of pathological immune complexes. …”
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18742
Table 1_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.xlsx
Published 2025“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”
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18743
Image 3_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif
Published 2025“…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…”
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18744
DataSheet1_Effects of mesenchymal stromal cells and human recombinant Nerve Growth Factor delivered by bioengineered human corneal lenticule on an innovative model of diabetic reti...
Published 2024“…In the last years, mesenchymal stromal cells (MSCs) and neurotrophins like Nerve Growth Factor (NGF), have garnered significant attention as innovative therapeutic approaches targeting DR-associated neurodegeneration. …”
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18745
Table 2_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.xlsx
Published 2025“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”
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18746
Data Sheet 1_Unilateral biportal endoscopic transforaminal lumbar interbody fusion versus minimally invasive transforaminal lumbar interbody fusion for single-level lumbar spondylo...
Published 2025“…Compared with MIS-TLIF, ULIF demonstrated significantly reduced intraoperative blood loss [WMD = −35.71, 95% CI (−51.80, −19.63), p < 0.01], fewer intraoperative fluoroscopy times [WMD = −1.29, 95% CI (−2.56, −0.02), p < 0.05], lower postoperative drainage volume [WMD = −20.64, 95% CI (−37.13, −4.15), p = 0.01], shorter postoperative ambulation time [WMD = −0.30, 95% CI (−0.42, −0.17), p < 0.01], and decreased hospital stay duration [WMD = −1.50, 95% CI (−2.09, −0.90), p < 0.01]. …”
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18747
Table 6_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.xlsx
Published 2025“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”
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18748
Table 4_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.xlsx
Published 2025“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”
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18749
Data Sheet 2_Unilateral biportal endoscopic transforaminal lumbar interbody fusion versus minimally invasive transforaminal lumbar interbody fusion for single-level lumbar spondylo...
Published 2025“…Compared with MIS-TLIF, ULIF demonstrated significantly reduced intraoperative blood loss [WMD = −35.71, 95% CI (−51.80, −19.63), p < 0.01], fewer intraoperative fluoroscopy times [WMD = −1.29, 95% CI (−2.56, −0.02), p < 0.05], lower postoperative drainage volume [WMD = −20.64, 95% CI (−37.13, −4.15), p = 0.01], shorter postoperative ambulation time [WMD = −0.30, 95% CI (−0.42, −0.17), p < 0.01], and decreased hospital stay duration [WMD = −1.50, 95% CI (−2.09, −0.90), p < 0.01]. …”
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18750
Table1_Adverse event signal mining and severe adverse event influencing factor analysis of Lumateperone based on FAERS database.docx
Published 2024“…Conversely, concomitant use of CYP3A4 inhibitors or drugs metabolized by CYP3A4 was associated with a decreased risk of severe AEs (OR = 0.524 [0.434, 0.633], P = 0.000).…”
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18751
Data Sheet 1_Cross-species analysis of FcγRIIa/b (CD32a/b) polymorphisms at position 131: structural and functional insights into the mechanism of IgG- mediated phagocytosis in hum...
Published 2025“…In contrast, allele-specific effects in macaques were highly significant; the macaque P<sup>131</sup> variant showing uniformly reduced IgG affinity. …”
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18752
Table 1_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.docx
Published 2025“…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…”
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18753
DataSheet1_Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD.doc
Published 2024“…Moreover, erlotinib treatment decreased astrogliosis in 6-month-old PS19 mice and reduced proinflammatory responses in primary astrocytes (PACs) from PS19 mice. …”
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18754
Table 5_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.xlsx
Published 2025“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”
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18755
Table 1_The knowledge paradox: an inverted U-shaped association between HIV knowledge and stigma among older men in Sichuan Province, Southwest China.docx
Published 2025“…Background<p>Older men (≥50 years) in China face elevated HIV infection risks, yet HIV stigma remains a significant barrier to prevention. Although HIV knowledge is frequently assumed to reduce stigma, the evidence is inconsistent. …”
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18756
Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx
Published 2025“…Meanwhile, NADPH+ production and G6PDH enzyme activity significantly decreased. Further study validated that metformin inhibited the cell growth of GBM cell lines through up-regulating PER2 and inhibited SIRT2/G6PD signaling pathway, enhancing radiotherapy(RT) sensitivity. …”
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18757
Table 3_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.xlsx
Published 2025“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”
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18758
DataSheet1_Probiotics combined with prebiotics alleviated seasonal allergic rhinitis by altering the composition and metabolic function of intestinal microbiota: a prospective, ran...
Published 2024“…From baseline to day 91, mean difference between groups (MDBG) in the reduction of TNSS was -1.1 (-2.2, -0.1) (P = 0.04); MDBG in the increment of TNF-α was 7.1 pg/ml (95% CI: 0.8, 13.4, P = 0.03); the INF-γ level was significantly increased (P = 0.01), whereas that of IL-17 (P = 0.005) was significantly decreased in the test group, whilst mean difference within groups was not statistically significant in the placebo group; MDBG in the increment of acetate was 12.4% (95% CI: 7.1%, 17.6%, P <0.001). …”
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18759
Table 1_Evaluating the Implementation of fan-beam CT-guided online adaptive re-planning in definitive cervical cancer radiotherapy.docx
Published 2025“…This approach has shown significant improvements in dose distribution and the potential to provide clinical benefits by reducing acute toxicity.…”
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18760
Genetic and structural factors contributing to the dominance and persistence of goose astrovirus type 2
Published 2025“…<p>Goose astrovirus (GoAstV) has emerged as a significant pathogen affecting the goose industry in China, with GoAstV-2 becoming the dominant genotype since 2017. …”