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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant genes » significant gender (Expand Search), significant benefits (Expand Search), significant changes (Expand Search)
significant main » significant gap (Expand Search), significant amount (Expand Search), significant cause (Expand Search)
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201
Table 1_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx
Published 2025“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”
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202
Image 1_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.tif
Published 2025“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”
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203
Table 3_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx
Published 2025“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”
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204
Table 6_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx
Published 2025“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”
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205
Table 5_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx
Published 2025“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”
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206
Table 7_Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes.xlsx
Published 2025“…In addition, PLE had the effect of increasing the estradiol content and decreasing the luteinizing hormone content in the serum of rats, and the administration of 160 mg/kg of PLE also significantly increased the 5-hydroxytryptamine content in the serum of rats. …”
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207
Table1_Berberine alleviates ETEC-induced intestinal inflammation and oxidative stress damage by optimizing intestinal microbial composition in a weaned piglet model.docx
Published 2024“…ETEC infection significantly upregulated the expression of genes coding for Nrf2, CAT, SOD1, GPX1, GST, NQO1, HO-1, GCLC, and GCLM in the small intestine of the animals (P<0.05). …”
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208
Table 1_To elucidate the effect of Ruanjian Qingmai granules on arteriosclerosis obliterans from the perspective of cholesterol efflux.docx
Published 2025“…</p>Results<p>Ruanjian Qingmai granules significantly decreased lipid deposition and significantly increased the expression of CYP7A1 mRNA in both zebrafish and HepaRG cells. …”
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209
Data Sheet 1_The CENPN/STAT3/USP37 signaling axis promotes invasion, migration and metastasis in nasopharyngeal carcinoma.docx
Published 2025“…</p>Results<p>The invasion and migration capacities of nasopharyngeal carcinoma cells decreased significantly after CENPN knockdown, whereas the overexpression of CENPN significantly promoted the invasion and metastasis abilities of nasopharyngeal carcinoma cells. …”
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210
DataSheet1_SGLT2i and GLP1-RA exert additive cardiorenal protection with a RAS blocker in uninephrectomized db/db mice.docx
Published 2024“…</p>Results<p>Semaglutide combined with ramipril and/or empagliflozin significantly decreased albuminuria but only when combined with both compounds, semaglutide further decreased blood glucose, glomerular hyperfiltration in male mice and glomerular mesangial matrix expansion. …”
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211
<b>Single-cell landscape of piglet lung response with </b><b><i>Actinobacillus pleuropneumoniae</i></b>
Published 2025“…In contrast, epithelial cells were significantly decreased and included those with features of epithelial-mesenchymal transition differentiated into fibroblasts through the signalling of TGFB1 and HIF1A. …”
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212
Data Sheet 3_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.xlsx
Published 2024“…The RT-PCR results showed that the expression of MMP9, HSP90AA1, SRC, EGFR, and ALB core genes in the control group was significantly upregulated, while the CASP3 gene was downregulated. …”
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213
Data Sheet 2_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.xlsx
Published 2024“…The RT-PCR results showed that the expression of MMP9, HSP90AA1, SRC, EGFR, and ALB core genes in the control group was significantly upregulated, while the CASP3 gene was downregulated. …”
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214
Table 1_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.docx
Published 2024“…The RT-PCR results showed that the expression of MMP9, HSP90AA1, SRC, EGFR, and ALB core genes in the control group was significantly upregulated, while the CASP3 gene was downregulated. …”
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215
Data Sheet 1_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.xlsx
Published 2024“…The RT-PCR results showed that the expression of MMP9, HSP90AA1, SRC, EGFR, and ALB core genes in the control group was significantly upregulated, while the CASP3 gene was downregulated. …”
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216
Data Sheet 1_Integrated metabolomics and network pharmacology analysis to reveal the mechanisms of Wenshenyang decoction in the treatment of chronic kidney disease.docx
Published 2025“…KEGG (Kyoto Encyclopedia of Genes and Genomes) enrichment analysis showed that WSY mainly affected linoleic acid metabolism, FcεRI signaling pathway, and unsaturated fatty acid biosynthesis. …”
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217
Supplementary file 1_Metal ion-enhanced photosynthetic bacteria for bioplastic production from kitchen waste digestate: performance and mechanism.docx
Published 2025“…</p>Methods<p>FeCl<sub>3</sub>·6H<sub>2</sub>O and MnCl<sub>2</sub>·4H<sub>2</sub>O were the main sources of Fe<sup>3+</sup> and Mn<sup>2+</sup>. …”
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218
Data Sheet 2_Cellular effects of splenectomy on liver regeneration after 70% resection.pdf
Published 2025“…Splenectomy also correlated with decreased rates of Ly6C+ monocyte and Ly6G+ leukocyte migration. …”
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219
Data Sheet 1_Cellular effects of splenectomy on liver regeneration after 70% resection.pdf
Published 2025“…Splenectomy also correlated with decreased rates of Ly6C+ monocyte and Ly6G+ leukocyte migration. …”
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220
Table 1_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.docx
Published 2024“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”