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121
Table 1_IP-10 acts early in CV-A16 infection to induce BBB destruction and promote virus entry into the CNS by increasing TNF-α expression.docx
Published 2024“…Moreover, in a suckling mouse model, IP-10 and TNF-α treatments exacerbated clinical symptoms, mortality and pathological changes in the brain of CV-A16-infected mice, but Anti-IP-10 and Anti-TNF-α treatments alleviated these changes. …”
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122
Supplementary Material for: Protein inhibitor of activated STAT 2 (PIAS2) protects against podocyte injury in diabetic nephropathy via inhibiting JAK2/STAT3 pathway
Published 2025“…Overexpression of PIAS2 significantly reversed high glucose-induced human podocytes injury, evidenced by increased cell viability, reduced cell apoptosis, decreased expression of pro-apoptotic proteins Bax and cleaved-Caspase3, increased expression of the anti-apoptotic protein Bcl-2, and reduced secretion of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. …”
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123
Data Sheet 1_Cerebrospinal fluid and serum cytokine profiles in severe viral encephalitis with implications for refractory status epilepticus: a retrospective observational study.d...
Published 2025“…CSF IL-6 and IL-8 levels were significantly elevated in the RSE group compared to patients without seizures and with controlled seizures, decreasing gradually and independently of serum cytokine levels. …”
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124
Supplementary file 1_Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III tria...
Published 2025“…</p>Conclusion<p>Ivarmacitinib significantly reduces the need for adding/escalating medications compared to placebo, thereby potentially decreasing treatment burden. …”
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125
Image 1_Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III trial.tif
Published 2025“…</p>Conclusion<p>Ivarmacitinib significantly reduces the need for adding/escalating medications compared to placebo, thereby potentially decreasing treatment burden. …”
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126
Supplementary file 1_Cistanche tubulosa glycosides ameliorate cognitive decline in APP/PS1 mice via modulation of gut microbiota and fatty acid metabolism: insights from multi-omic...
Published 2025“…</p>Conclusion<p>This work uncovers a novel “gut microbiota-fatty acid metabolism-neuroinflammation” axis as the primary mechanism underlying GCT’s anti-AD effects. These findings highlight GCT’s therapeutic potential and offer new mechanistic insights into how low-bioavailability phytochemicals exert systemic benefits via the gut-brain axis.…”